This is, in my opinion, the most valuable article on DMSO I've seen yet. The therapeutic possibilities here are truly incredible—limited only by our imagination. Importantly, this isn’t just information for healthcare professionals; it’s accessible to everyone. If people approach this with courage and follow the guidance, we really do have a chance to reclaim our health from the traditional medical system. In my own practice, I now use DMSO or a DMSO combination in about 80% of cases, and the results have been remarkable. The potential for self-healing outlined in this article is inspiring. Save it, print it and keep a copy nearby.
Working with editors is very challenging because they will often change your intended meaning and it can be difficult to catch the change that was made if it's subtle in a large body of text. In the case of Harmut Fischer's work, all of it, except his 2015 book, is in German and hence not very accessible. However his 2015 book is in English and hence is one of the best references on the market. I apologize for the intended meaning getting changed in the final version.
She keeps posting that to get traffic. It's highly inaccurate, but each time we try to explain (along with dozens of readers who have tried as well) the specific points, she says we are brainwashed by the medical field and don't understand what we are talking about (along with telling everyone who says DMSO helped them a lot and had no side effect that their experience, for one reason or another, doesn't count).
Her brand essentially is saying commonly used natural therapies are actually toxic and you need to just do detoxs and elimination diets, so if you go through her Substack, you will find some pretty ridiculous stuff used to smear other therapies. When I looked at her arguments, I realized that she was juxtaposing common issues with other pharmaceuticals onto DMSO (which is a common thing people do, as due to it being hard to fully understand a subject, they always juxtapose their pre-existing knowledge base onto it).
Regarding the deaths, the points she's omitting is that in all but one of them, another product was involved, as on FAERS if someone has a lethal reaction to a drug, they list all the other things they were taking as well, and in those cases, it was more likely culprit of death, and in many cases, they were being given intravenously (where a higher risk of death, particularly the onyx cases where the DMSO polymer mixture was being used to patch an otherwise fatal internal bleed and hence was a high risk situation). When I wrote the safety article, amongst other things I read through all the FAERS reports and explained them, no one else has done that. Conversely, most medications have thousands of deaths in FAERS, many of which can be directly attributed to the drug. The fact that over roughly 40 years 21 deaths are in there almost none of which can be attributed to DMSO is an insane safety profile. The primary drug DMSO replaces (NSAIDS like ibuprofen) are well recognized to kill hundreds of people each day, and their toxicity is rarely discussed.
In short read these two article, critically compare them to hers and then make your own decision:
Decided a while ago to try a teaspoon internally. After a few days, amazingly, I noticed I wasn't coughing! I'd had a regular chronic cough almost all year! And the cough is gone! Thanks so much, Doc! I had been told I had beginnings of heart failure, and a cough sort of goes along with that. I'm feeling much more confident! Workout three days a week going a mile on treadmill, and i'm 82. 😊
For anyone interested, here's some information on making a 12% magnesium chloride solution to be mixed with DMSO for musculoskeletal and other issues.
I could only find two liquid magnesium chloride solutions online, one from Nutricology and one from GNC. I contacted both companies asking for the percentage of magnesium chloride in their product, and neither replied.
So I decided to buy magnesium chloride flakes. I ended up buying a 50-pound bag of magnesium chloride from an industrial supplier (MgCl is used for deicing roads), but you can buy small quantities from companies such as Greenway Biotech (e.g. see their Organic Magnesium Chloride USP).
As for making the solution, "12%" refers to weight, not volume. So you'll need a gram scale to weigh the magnesium chloride, preferably one that measures to the hundredth of an ounce. I decided to make the solution using 24 fluid ounces of water. You can find a converter on the Internet to easily get the weight in grams for any volume of water.
Knowing the water weight in grams, you can obtain the weight needed for magnesium chloride by applying the following formula: (Weight of water in grams)=.88X. Here "X" will give you the total weight of the water+magnesium chloride combination. Then subtract the water weight from "X"--this will give you the weight of magnesium chloride in grams needed for the solution.
Then you just weigh out the magnesium chloride flakes on the gram scale (I measured to the hundredth of an ounce, but of course you don't have to be perfect). Then dump the MgCL flakes into the water and mix with a spoon until the flakes fully dissolve--this only takes a couple of minutes.
And that's it--you've got a 12% magnesium chloride solution.
(Edited: Please disregard my previous post, as I mentioned a product that I mistakenly thought was a liquid (it's actually a solid).)
It looks like you can't buy a commercial preparation of D-lactic acid at 21%. I found two liquid formulations of this product online: Neogen's Megazyme D-Lactic Acid Standard Solution and R-Biopharm's Enzytec Liquid D-Lactic Acid.
The spec sheets for these products don't specify the percentage of D-lactic acid, so you'd have to contact these companies to obtain this information. If they provide you with the percentage of D-lactic acid in their product, then you can make your own 21% D-lactic acid using water as a dilutant.
You can use the following formula: (C1) (V1)=(C2) (V2).
Here C1 is the concentration of the starting solution, V1 is the volume of the starting solution, C2 is the desired final concentration, and V2 is the desired final volume.
So let's say you're using a 99% D-lactic acid solution and you want to make 20 fluid ounces of 21% D-lactic acid. You'd use the following values in the above formula: C1=99, C2=21, V2=20.
Then you'd solve for V1--the answer here is: 4.24 ounces. So you would use about 4.25 ounces of a 99% D-lactic acid solution and 15.75 ounces of water to yield 20 fluid ounces of 21% D-lactic acid.
If Neogen or R-Biopharm fail to provide you with the percentage of D-lactic acid in their product, then you would have to make your 21% solution using a weight instead of a volume calculation, which is a bit more complicated.
On Friday, I disturbed an old disintegrating stump by kicking it. A piece fell off and a swarm of wasps came out charging me. I had on socks and Jeans, Many got me on my ankle through the stocking.
I got into the house and immediately put DMSO on a cotton ball and held it on my ankle. Also put some DMSO on my whole foot. It never swelled up, pain resided, Still tingled some for a few hours. Slept well overnite without pain, and next morning, could not feel anything. Thankful I had the DMSO available.
Thank you AMD, for this huge effort. I am currently planning to use many of the snippets of information found herein to prove out some additional uses for DMSO. One of those will involve the use of Red Elderberry, I found recently in abundance on my mountain. My wife told me not to eat them, because their seeds contain cyanide (edited 23 AUG 2025 TO REMOVE ERRONEOUS MENTION OF ARSENIC)... actually similar to the apricot seed and apple seed. When I considered this fact, I realized that B17 has been used, (Laetrile) to treat cancer, and was buried by the system. These Red Elderberries are quite delicious, and would be a very pleasant way to treat cancer, combined with DMSO. Another project I've started to work on is the use of catechins from the Red Alder... a little bit bitter to taste, and woody, but edible. Because the alder is a very unique tree, when the bark is removed it turns color, a deep red... another natural dye, and as you noted, several natural dyes are in fact used to treat cancers. So, thanks again for all the knowledge you've shared... we will set forth and put that valuable effort you have expended to good use. God Bless you.
Thank you! Let me know how it goes. That said, in the case of Laetrile, the reason it "worked" was that while it was "toxic" it (allegedly) only released cyanide in tumors, so it had a selective toxicity for cancers. That's different from taking something which is just toxic in general.
Thanks a lot Doc. I will stay in touch. BTW, cabbage family group, cruciferous veggies, also contain "toxic" compound isothiocyanate... so deadly, I am told, that it cannot be transported on public lines... yet it is active in stopping the growth of tumors... and I eat some pretty much daily... another great candidate for compounding with DMSO. I have been growing cabbages for personal use... (I'm not kidding here... two years ago, my cabbages reached an amazing 53" in circumference, and a weight of 28 pounds!) I have lots of sauerkraut for healthy food. I am grateful for all you do Doc. Thank you again.
Sure Laura, no problem. Ingredients: Fresh cabbage, clean, shredded, and salt TO TASTE, (not necessary to have a lot, because fermentation is the preservation process, not salting.
THE PROCESS: In a large bowl, (we use stainless steel), add layers of cabbage about 1-1/2" deep, with some salt, and then bruise the mixture with a wooden club, like the end of a baseball bat, to force juice to show abundantly. When you have sufficient cabbage bruised, add it to a one quart mason jar... (any size will work fine), and PACK THE BRUISED CABBAGE INTO THE JAR TIGHTLY, using an appropriately sized wooden 'bat'. The idea is to fill the jar to about 1'' from the rim, making certain that the cabbage is tightly packed, AND, that there is juice covering the cabbage. I leave a 1/2" space between the lid and the top of the juice. Note that you may add other things, like shredded carrots, peppers and such during the mixing process. After wiping the rim of the jar, put on the Mason jar lid, and tighten the lid about finger tight, wipe the outside of the jar clean, and place it into a tray, a cookie sheet is fine, to catch the expelled juice during the fermentation. Ferment on the kitchen counter, or any shelf, at room temperature, warmer is O.K., but cooler will slow or stop the fermentation, which generally, and usually takes about a week after stuffing the jars with cabbage. This method is very reliable, hassle free, and the resulting sauerkraut lasts a long time, without refrigeration. After opening the jar for use, however, refrigeration is recommended. DELICIOUS... It is noteworthy that sauerkraut made in different homes tastes differently, likely due to different biomes in each home. A note about the process... the concept is to ferment in the absence of air... so tight packing is important, juice over the cabbage in the jar, and the right amount of pressure when putting the lid on. The gas from fermenting will force it's way out of the jar by forcing the lid to give a bit, while preventing air from entering the jar... it works very well. When the fermenting is done, gas stops forming. Wipe the jars again, label them with the date, and then store them in a preferably cool place till they are needed. The longer the sauerkraut stays in the jar, the richer the flavor. We've used sauerkraut done this way for many years, and can use the finished product in from about one week up to several years. We've not had even one failure. WE DO NOT PROCESS AFTER FERMENTING, BECAUSE THAT KILLS THE PROBIOTICS IN THE SAUERKRAUT. I hope this was helpful Laura. All the best.
Doc, just to let you know one of your readers noticed I used the word 'arsenic' erroneously, instead of the intended word 'cyanide'. I did apologize for my error, I hope not to make another mistake. (Editing done 23AUG225 replace the word 'arsenic' with the word 'cyanide'). Sorry for the mix-up, and thanks again for all your work you've been generous to share with us.
Thanks Isabela, all the best, and God bless you. By the way, thanks for the advice on how to safely use the Elderberry. Mine are wild, Red Elderberry, up on my mountain, and they showed briefly, for the second time, and got my attention this year... I have found them in four locations, and now plan to propagate them. In noticed that the birds and the black bears eat them very quickly, and realized they must have medicinal value. I have a sense that the CYANIDE in the seeds may actually be useful for cancer treatment, and note (jokingly) that I haven't seen any birds or black bears with cancer... thanks for being a good sport Isabela. (yes, not arsenic... oops).
Hello, a correction needs to be made here....elderberries Do Not contain arsenic. My husband and I grow 5 acres of black elderberries. The elderberries contain Cyanogenic glycosides (CNGs)....let me quote from the journal Molecules: "CNGs are naturally occurring plant molecules which consist of an aglycone and a sugar moiety. Hydrogen cyanide (HCN) is released from these compounds following enzymatic hydrolysis causing potential toxicity issues." However, once the berries are harvested and de-stemmed and cooked at 160 degrees for about 20 minutes the HCN is neutralized. We harvest the berries, de-stem them (with a machine) and juice them and freeze the juice which is cooked later. It is not advised to eat the raw berries. The seeds should be strained out of the juice before or after they are cooked. Probably not good to ingest all that seed material, might be problematic for people with gut issues like diverticulitis.
Sorry Isabela, I did mean to say cyanide, not arsenic. My brain is not working right since I gave myself a concussion in May 2025. You are entirely correct, please accept my apologies, to you and all the folks I've inadvertently misinformed. Perhaps I should get more sleep. Thank you for your sharp eye, kind correction, and watching out for the truth. Much appreciated. (I apologized to my wife also... she did say cyanide, not arsenic... she also insisted on that CT SCAN the day after the concussion... she said she knew something was "not right" when I told her I had knocked myself out in the garden on the bucket of the excavator... the day before, and forgot to tell her about it.) Thanks for covering my 'six'.
Hi, we grow Bob Gordon, Marge, Pocahontas and Ranch. We originally got our plants from Indiana Berry co. We propagate them ourselves now. They are very easy to propagate in the Spring. We take cuttings from the dormant stems and put them in moist soil in pots. They root easily. Our de-stemmer came from
The de-stemmer wasn't inexpensive, but if you search around you may be able to find one cheaper. If you freeze the berries first in bags it can be easier to remove them from the stems. If you are only doing small amounts of berries you probably don't really need a de-stemmer. Elderberries are totally worth having on your property. The flowers are great for the pollinators and are also usable
for tea and other things. Of course you wouldn't want to harvest all of the flowers because then you'd have no berries. All around a great plant!
Hi Deb, yes, there has been mention of injecting DMSO under controlled conditions. (I have to be careful, I am still apparently under the effects of a concussion). It was Dr. Stanley Jacob, I believe who mentioned it. Here is a snippet from Google:
What is the use of DMSO injection?
DMSO is used either alone or in combination with a drug called idoxuridine to treat pain associated with shingles (herpes zoster infection). Intravenously, DMSO is used to lower abnormally high blood pressure in the brain.
I am unable to recall all of the applications that were mentioned, but if you Google Dr. Stanley Jacob, there is a wealth of information available. All the best, David.
Another testimonial - my 8lb cat recently sprained her hind paw and a had a minor abrasion on it as diagnosed by xray. I applied 50%dmso directly to the paw twice a day for 3 days while also giving her two drops of comfrey leaf tincture in her food twice a day for 5 days. She showed immediate improvement in one day and her limp was completely gone by day 2.
DMSO is an enemy of The big Pharma protocols for drugs and injections. DMSO in plastic bottles will probably leach out Bis Phenyl A , an estrogen interrupter that is resident in plastic bottles wall surface. through the molding process of the bottle. It is interesting to note that DMSO is excreted through the kidneys and is not impacting hepatic function. Most of the prescription drugs that are consumed today. do just the opposite.
I have found using a topical form of a pain reliever in the form of a gel and mixing it in equal amounts with pure DMSO allows me to sleep all night .
It is a blessing. The only question that I have is that the half life of DMSO is 2 to 3 days.. therefore is there a risk of overdosing on DMSO and what are the consequences?
In the pharacokinetic studied they have not found regular DMSO use causes it to reach excessive levels in the body. Conversely it's also unlikely anyone will ever get near a toxic dose because it's LD50 is so high (e.g., the prisoner study covered their entire body with DMSO multiple times a day for 90 days and there were no issues).
I buy Voltaren gel from Costco under their generic brand! Then I buy 99% DMSO @Amazon and mix them together in equal quantities. I think it’s working for me rather than taking Voltaren by mouth and having it spread through the whole body.
What about the inactive ingredients in the gel? I see Fragrance, Polyoxyl 20 Cetostearyl Ether, Propylene, and Strong Ammonia Solution listed, among others. No negative reaction from these being transported into the body along with the diclofenac?
DMSO is metabolized to DMSO2 which appears in the urine. AFAIK there isn't an indicator for that yet (like with pH indicator) but that would be feasible, with color shades for concentration. When IR spectroscopy is available that also would work well to get to know the range for safe level as the absorption spectrum of dimethylsulfone is specific.
Oh, thanks for the reminder. I previously took it orally and found it kept me awake. I've been putting it on my scalp at night now and that's probably why I'm not sleeping well.
Sue, do you put the DMSO alone on your scalp or combined with something else? Once a week, I mix DMSO with a hair oil that is supposed to promote growth, but I've not been doing it very long. Do you notice any hair changes with the scalp application, such as greater growth or change in hair color? Thank you.
Almost 4 weeks ago, I went to get on my daughter's treadmill. She usually helped me. Well, I hit the wrong button and it went so fast that I wound up on the floor. I did not break any bones, but my ankles and top of my thigh got scraped up pretty bad. It has been rather painful and I should have asked my daughter to use DMSO. I am healing, but I think that I would have healed faster, if she had used it and would not have been in so much pain. She used all kinds of other things like colloidal silver, fresh aloe vera from a plant, etc. I had no desire to go to ER and be treated. A neighbor across the street went there for a leg problem. Something went wrong and. he had to have his leg amputated.
Very impressive!!!! and overwhelming. However, I bet classically trained western physicians would be more overwhelmed than I am!
I wish to add one factor, a biophysics phenomenon best illustrated by a UV light shined on the body. I apologize up front that this is longer than I would have wanted because it brings many concepts together: A UV light projects quanta of high energy that are absorbed by the body and create an increasing concentration of OH• (hydroxyl radical) in the body. This is quite similar to the biochemistry described as "metabolic syndrome". For the past 20 years, I have studied this energy as a form of energetic pollution that is carried by the air and is in equilibrium with the human body. Car engines produce massive amounts of this, which is one of the reasons why people in cities tend to have high levels of chronic metabolic disorders than those far away from major roadways. I have developed a variety of devices that can absorb this "free radical" energy from air, magnetic fields, and copper wires. (EMF sensitivities). I also have devices that draw it from the human body. The result is a gradual reduction of oxidative end products like cataracts.
OK. On to DMSO. Based on your articles I purchased a jar of 100% DMSO gel. I was amazed at the burning sensation of my skin. (a new phenomenon to study!!!) I discovered that younger people have less of that burning than us older people, suggesting that this phenomenon accumulates with aging. Was this related to that energetic pollution I had been studying?
I applied DMSO to a small patch of stiff muscle and waited for the burn to show up. When it did, I applied one of my electromagnetic devices (that vacuums out this ionizing energy) to the center of the patch. The sensation immediately shifted to a more comfortable tingling, and to my amazement, lasted 1/2 hour or more. To me, this meant that the DMSO was dissolving old deposits of free radical end products like AGEs and releasing the quanta of high energy stored in the bonds of the free radical end products. It seemed this energetic pollution was flowing to my device from an expanding area of the body as the DMSO penetrated through the body dissolving free radical end products in it's path. This suggested to me the possibility that such a combination of DMSO and extraction of quanta of oxidizing energy might be a form of rejuvenation.
Then someone introduced me to the little H2 infused water generator bottles available for $30 on Amazon. As I studied them, they work by having H2 gas combine with OH• (hydroxyl radical) which forms water molecules within a rich mix of aqueous electrolytes, converting that oxidizing energy to heat energy dissipating harmlessly into the body. I found that, if I drank a few ounces of the H2 infused water, waited 1/2 to 1 hour, then applied the 100% DMSO, I got absolutely no burning. A Grok study showed me that, by greatly reducing the hydroxyl with the H2 water, I was initiating a cascade of reduced free radical levels of lower oxidizing potentials in my body as well.
Based on this I propose that DMSO combined with antioxidants might work better in reducing inflammation because DMSO alone releases the high energy potentials from dissolved free radical end products back into the body contributing to the pool of oxidative agents like hydroxyl which then just re-form new free radical end products in other parts of the body.
For those who don't get skin burning from DMSO, this might seem unimportant, but for us old people with a lifetime of accumulation of free radical end products like AGEs, this combination of DMSO with H2 water or perhaps another form of hydroxyl level antioxidant might provide a major reversal of one of the forms of aging.
Thanks for this. I noticed that after bathing in a chlorine dioxide solution several times, I get far, far less burning than I used to when I apply 100% dmso to my skin.
Hydroxyl radical reacts with almost anything, so I would think its end products can be anywhere you look. 2a. For Hydrogen Water Bottle, type Hydrogen water bottle into amazon. for my devices go to chi.us
I rolled full strength DMSO on my face. It really burned but in 5 minutes the pain was gone and so was the terrible sinus congestion I was trying to treat. It did leave my skin irritated but I would do it again.
I used the 70% gel on small areas of my face (I read your warning and stupidly ignored it). I was freaked out slightly when my face started swelling but I just added more aloe and it calmed down and the next day was fine. But the amazing thing was that I had noticeable mental clarity (I have constant brain fog and chronic fatigue) so that was a happy accident! I also applied it to a pimple that was completely gone the next day.
Props to you for persevering. 70% gel on my face is about all I can stabd for the first 10 minutes. But to clear terrible sinus congestion, it would be worth it.
Is your sinus congestion from a cold or allergeries? Mine is just because I'm congested. I've tried everything from xylitol sprays to steroid sprays to flushing with NS to oral sudafed (the strong one) to antihistamines. I hesitated to use the DMSO because what I read was for sinus issues. PS I was diagnosed with a deviated septum and had a septoplasty over 3 months ago, well, I'm still congested!
Wow! This article is so timely for me! I'm at the end of a "course" of Lion's Mane which I use in 3-4 month stints for Parkinson's - after which time it stops being effective. At this point I was not sure what "experiment" I was going to try next - but with this information I'm inspired to try mixing DMSO and Lion's Mane. DMSO alone has been effective for pain, muscle fatigue. We will just have to see what this combo turns up. Thank you for your amazing contribution to humanity!
Thank you for all the time spent on this article, it is Invaluable!!! The possibilities are endless. I have printed it off and now can spend the time reading!
I've commented before on success with DMSO, but three days ago I had to put it to a much bigger test. A teeny fragment of bone is resting on the nerve near my C-4 vertebra. This situation came on fairly suddenly, and one false move takes me from discomfort to white knuckle pain that has me sobbing and gasping for breath.
After a day of this hell (which standard pharma pain meds barely touched), I suddenly remembered my DMSO. I used 10 ml of an 80/20 solution, used a dropper, applied to my skin and rubbed it in.
After about 15-20 minutes, I started to feel it work. Soon most of the pain was gone. GONE. I could walk upright, move my left arm. Anyone who has had nerve pain knows how difficult it is to get any relief at all, yet DMSO has made it possible for me to function with almost no pain as I wait for my next doc appointment (to take care of the problem for good).
The information you provide here is a public service, and you are making a huge difference in people's lives, MWD. Thank you from the bottom of my heart.
I have a forward curve in my neck and upper back that prevents me from raising my head, or turning it side to side. It is fairly painful. Today I applied a product from BearCat Body Care Essentials LLC
It consists of 50% DMSO, and 50% black Jamaican castor oil. I transferred it to a rollerball bottle for easier application. After applying it to my upper back and shoulders, it became warm, and within minutes the pain was gone, and I could raise my head without pain, as I have been unable to accomplish for four years
New Subscriber here. Thank you for your work and dedication to this topic, and the health of others. This is the most complete source I've found for using DMSO, and I am new to it. The dosing information and natural combinations you have here are an invaluable source. I look forward to being more self-sufficient int his area, and moving away from the medical 'treadmill'. Thank you again for your work.
Wow! I need to study this. My 98 year old father has such trouble sleeping and also has some dementia. We are going around in circles with the main stream health professionals. Meanwhile he suffers. I would love some help in using DMSO for him.
Debbie, I have had long time issues STAYING asleep and my latest and fairly workable solution includes spraying a Magnesium solution on bottom of my foot, rubbing it from that foot onto bottom of the other. I sleep pretty well with that. I used to take Benadryl tablets but found out there are some definite side effects that could be generated long term so stopped it. https://www.sevenminerals.com/products/sleep-well-magnesium-oil-spray-natural
I do the same with Magnesium oil, though I use a pretty small amount (just a spritz and then rub it in) on the back of the neck. Works especially well when I wake in the middle of the night and have trouble going back to sleep. Allows me to wake at a normal hour without any lingering grogginess, unlike Benadryl or melatonin.
I take cannabis infused coconut oil right before bed. It kicks in after I go to sleep and wears off before I wake up and helps me sleep through the night (but not fall asleep since it takes awhile to kick in)
I make some CBD tincture with MCT oil. I use Bubba Kush CBD flower. It works as well for me as the cannabis. So if you can’t get cannabis flower, this seems to work for sleep too. I also ground at daybreak which helps with circadian rhythm. To me, this has helped tremendously.
I make it as it is legal in my state (one ounce of bud to 2 cups coconut oil). I only need 1/4 teaspoon to sleep through the night but my husband takes significantly more. I use this recipe but started skipping the step of freezing it because it was too much trouble and I use sunflower lecithin instead of soy: https://dudegrows.com/make-potent-cannabis-oil-aka-canna-butter/. I take the leftover buds after squeezing out as much oil as possible and make tea.https://wakeandbake.co/weed-tea/. It's hard to control dosage with the tea. I drink slightly less than half a cup and then meditate once it kicks in. I routinely hallucinate on the tea as it is super strong for me(I don't use it every night as I don't want to get up the next day!) I don't know that others would though as I have drank ayahuasca previously and I think it primed my brain for hallucination.
If you're waking up between 3 and 4 pm, try taking milk thistle before bedtime. Your liver detoxes between 1 and 3, so toxins reach a peak of being dumped out a bit later, and whatever it's disposing of is waking you up. It's like when you do a parasite cleanse you might need to take Ornithine before sleep because of all the ammonia that forms when certain parasites die. Also consider not eating any carbs for dinner or later, because your blood sugar might be spiking, which will also wake you up.
I think the light researchers that suggest that late evening-before bedtime light should be 2500K or less (amber like a fire , candle,or low wattage filament bulb) are likely correct that our wonderful 5000K work lights and bluish screens are really messing up our melatonin sleep chemistry. Fortunately and unfortunately our holistic environment has massive influence on health and restful sleep. Lack of restful sleep is destructive for cognitive functioning.
I can see the need for an Encyclopedia of DMSO remedies. So I carefully looked, there should be a DMSO mixture for arthritic joints, what other components would be in the mix? I tried castor oil and dmso, didn't seem to do much, also tried ivermectin, the ivermectin stayed a white color on the skin, never did absorb, dmso went on first. Arthritis is an infection so I would guess substances to clear infections??? Regarding prostate inflammation and enlargement, how on earth could dmso be used, other than a topical mix as in a suppository?
Yes. Please write a book. A table of content would be helpful, and as well listing of mixtures and purchase locations (at least for reputable DMSO). I'd buy it for sure!
Duane Hayes: What i learned back in 1986 about arthritis...remove the cause! i was in intense pain and couldn't lift my arms...I examined my diet to see what could have caused it. I saw that I had been eating bread, since a neighbor who worked in a deli started bringing me some regularly. So, I stopped the bread and within two weeks, I was pain-free and totally flexible. A few months later, I decided to find out, if removing the bread was the answer, so I started using it again. Within a couple weeks, the same intense pain in my elbows and I could not lift my arms.. So, I stopped eating bread and grains...and within a couple of weeks I was home free again. ...no more pain and I could easily lift my arms. I don't take pain medication...so I can try and remove pain naturally. There is a very good book on the subject: Dangerous Grains by James Braly M.D. and Ron Hogan, M.A. It says that over 200 diseases are caused by eating grains...from Arthritis to Schizophrenia.
DMSO in combination with magnesium oil is a good combo for arthritic joints. You can find magnesium oil on Amazon. Amandha Vollmer wrote a book Healing with DMSO that has many remedies such as this. She also sells some of her remedies already mixed. I used her night cream and her scalp treatment. They are very good. You would learn a lot from the book.
Happy Body has a couple of creams that have MSM and CBD in them that I find help with my Rheumatoid Arthritis. I have also made some comfrey tincture that I apply with DMSO mixed with magnesium oil. I am not very good about applying it on a consistent basis.
Hey Duane, I have some experience to share with you, regarding your comments. For knees, elbows, shoulders... I have successfully, and repeatedly found using two capsules of the herb Horsetail daily helped me normalize in two weeks. A Neurosurgeon once asked me why my joints were so nice. It is slightly diuretic, and also improves A1C. Horsetail must not be taken fresh (raw) because it also contains nicotinic acid. Dried is perfectly safe. The active portion of the herb is silicic acid, the vitamin form of silicon, necessary for rebuilding connective tissue. Silicic acid is missing in Western diets mostly, I suspect... which would account for the very high rate of joint replacements. I avoided surgery on the acromion (in the shoulder) after one year of daily use, the shoulder healed completely. No notable side effects. SECOND POINT: Oral DMSO may also help the prostate, and I am guessing that the herb Stinging Nettle, combined with DMSO as a tea beverage would be very beneficial. I have used 1 tsp DMSO in 8 oz. water with no problem. I hope you find the cure you seek Duane. God bless you
DMSO's FDA approved version is known as Rimso, meant for instillation into the bladder. My M.O. is to get it as close to the target as possible. If that is not feasible, then internal routes are considered.
Wow, I've had so much information about this, but it's came in over many years and I don't have much to show my sources for this information. It is covered in the book, "Chronic" by Phillips and Parish. A short definition, a bacterium, or parasite, somehow invades our bodies, and where it's embedded, the infection causes a immune reaction, but this reaction goes into a auto immune reaction where our own immune system is now attacking our own cells at that location. Makes sense since only my right ankle and 4th finger and knuckle on the right hand have arthritis.
OK, everyone responds differently. I did three three-week protocol and still do maintenance doses. Helped with arthritis in hips and lower spine, healed my shoulder injury,(although it took almost a year), helped my low stomach acid.
DMSO NOTES
Brother sprayed DMSO after applying castor oil on the perineum and improved urine flow and frequency, but also did CD enemas and ozone suppositories. DMSO alone has worked for headaches, bunions, burns cuts, scrapes. Added with magnesium to reduce muscle soreness and leg cramps. Added with ivermectin improved acne and acne scars. Tried oral but wife wont let me take it as per the odor…😂
I am almost 70. I took a fall recently when I was out getting some sun because I was reading an article on my phone instead of watching where I was going. I fell over and broke the skin on one knee (through my jeans, no big deal) but also banged up my right hand. It was really painful and I thought I would have problems for weeks. Had lots of pain in my knuckles and the first phalanges when I closed my fist or used my hand.
When I got home I rubbed DMSO cream into the back of my hand and then later used 70% DMSO liquid and rubbed it into the back of my hand and into my phalanges.
Now, a couple of days later I cannot feel any pain!
I will be carefully reading this article for other cures using DMSO.
1) HAIR: what is the best combination for hair regrowth (other than finasteride)? Rosemary oil? How often to apply?
2) HRT: Have you heard of anyone using it with estradiol HRT cream (natural compounded cream)? And if so, do they have to lower their dosing? It is generally applied 2x per day indefinitely - is that disqualifying?
3) ECZEMA: used 70% gel with castor oil on my decades-old leg eczema and it healed it in one dose. (Notable that DMSO alone did not work. Had to combine with castor oil.)
1) I listed them here. The most commonly used thing is either DMSO alone or DMSO with MgCl2. We've also seen certain chinese herbal formuals (I don't currently have access to) and injected exosomes be very helpful. Finasteride causes a lot of problems...
"Hair Loss and Scalp Health: MgCl₂ is often used to enhance DMSO hair restoration (e.g., with a spray of 10–15% DMSO diluted with 12% MgCl₂ is massaged into the scalp before washing or overnight). Additions like vitamin C, B12, sodium gluconate, rosemary oil or peppermint oils are occasionally included to enhance effects.
Note: thicker hair and reversed graying has been reported with DMSO, vitamin C, and L-lactic acid."
2) I haven't suggested it for estrogen, progesterone or testosterone because those already absorb with topical preparations, so DMSO is not needed and would make it much harder to ensure you were following the correct dose.
Thanks for another phenomenally thorough article. A quick (albeit nitpicking) question, let's say you've applied DMSO to your joints 2-3 times a day for ten months. Then you want to try the DMSO/magnesium chloride combination, but you want to take some time off to offset any tolerance you've developed to DMSO over ten months.
Would two weeks be an appropriate waiting period for this purpose, or would a longer period (such as a month) be better? Thanks for any reply.
Yes as Mouzer mentioned, the doctor wrote the following (in the June 21 article entitled "Therapeutic DMSO Combinations Revolutionize Medicine"): "With both topical and oral DMSO, people generally find that as time goes on, their tolerance to it improves. Conversely, if it’s used too frequently, a tolerance can develop, so it’s generally advised not to take it 1-2 days a week."
Personally I plan on hitting my wrist injury 2-3 times per day with DMSO/magnesium chloride for at least four months before reducing the frequency. Since I already used DMSO daily for ten months straight, I was looking for a ballpark hunch on how long I should wait to overcome any tolerance that developed.
The magnesium chloride improves the effectiveness of DMSO for some people in regards to treating scars, wounds, musculoskeletal issues, and other conditions.
Edit: You can find more details about magnesium chloride in this article.
For decades, I experienced mysterious, intermittent left eye pain, that could only be relieved by immobilising the eye, and sometimes only by also mobilising myself in an upright position. The pain contributed to regular severe sleep disruption.
Differential diagnosis was sinusitis, migraine, or some seemingly undiagnosable eye problem. Attempts to resolve included ophthalmologists, ENT, sinus surgery, analgesics, antihistamines, decongestants, migraine meds and eye drops.
In 2018, I started with an integrated medicine doctor and within short time, migraines, and sinus problems resolved. Still the mysterious eye pain.
2024 saw me cycle through three practitioners at a large, major eye specialty clinic. All they could offer was a diagnosis of dry eye, lubrication, steroids, and antibiotics. Finally, I got to visit them on a “bad day“ and they could see evidence of a past trauma in the eye with an oval shape. They only cause of that trauma that I could think of was a 1974 incident where a piece of glass from a broken fluorescent tube was lodged in my left eye for a couple of days. Their final solution this year was ongoing antibiotic drops and review in three months! No way! They didn't investigate DMSO when I offered AMD's info.
Three months ago, I started with DMSO at 20% in an isotonic saline, morning and evening, along with preservative free lubricating drops, I was getting the best pain management ever! Sleep improved.
I reduced this to once a day and when needed for pain relief. The lubricating eye drops were "semi-natural" according to Chat GPT. A Schirmer Test this week showed tear production in the left eye at 7. Previous high was 4. The right eye had always been above 10 which is considered healthy.
I have just started on more natural Oculocin eye drops(propolis, aloe vera, chamomile) co-administered with DMSO. I'll report back in a few months ! Thank You AMD!
I'm trying to use it for a sudden scalp issue, extreme itching. But haven't found much detail about how to use it on your scalp so just using trial and error. Any advice?
And it sounds here like it would primarily be internal for treating lymel? Breaking down biofilms sounds great in theory, but usually breaking them down causes more herx symptoms.
1) Use a low concentration and then increase. Head is more sensitive.
2) With Lyme, it's normally internal. Like many other lyme things, you have to start with a low dose and work up to your tolerance. DMSO can help with herxing, as can zeta aid or lymphatic work, but most important thing is just not to dose too high especially at the start.
Might go without hair products for awhile. Especially if using DMSO. Many have no business being applied to the scalp. Several skin issues improve when chemicals are removed. Remember, the skin is reflective of the internal environment, and its a signal that something is awry. Dr. Hanes Ely had a very interesting theory on this.
Perhaps try Borax shampoo. The 20 Mule Team product from the laundry aisle. Re-use an old squeeze bottle, put in a few tablespoons of Borax, fill with hot water and shake a few times as it cools. It's okay if some powder is left unmixed. Apply to wet hair - it only lathers if the hair is dirty/has been a few days since shampooing. To rinse out, use a dilute vinegar rinse or citric acid (about 1/2 teaspoon in a cup of water - easy to keep a container in the shower to mix). May report hair is more curly after this!
Thank you. Can you explain the purpose of this? Is the Borax to clean the hair without chemicals, or because it has its own properties (like I know it is antifungal.) Vinegar is supposed to calm it, I believe. I did try it originally and it didn't work.
Borax removes buildup (from oil secretions, hair gel, etc.). Our scalps got in trouble when Hurricane Helene knocked out our water-to-the-house for a couple of months and shampoos were delayed way beyond the usual shampoo routine. Borax - more often than the once-a-week-Helene shampoo schedule - has cleared up various issues like buildup on the scalp. It's inexpensive! No worries about petrochemicals or artificial ingredients.
Last year I suffered terribly from scalp itching and eventually narrowed it down to drinking tap water (I am in the UK). Moving onto bottled water stopped the itching completely. I now use a water filter (just in a jug) which also seems to work really well. We have very hard water and a high nitrate concentration locally. My daughter also gets eczema from drinking our local tap water.
Amahnda Vollmer published a book on DMSO with a scalp treatment with DMSO and some other ingredients. I don't think it would hurt to just make a 50% dilution with distilled water and spritz that onto your scalp. With eczema and psoriasis it is all about watching your sugar and refined carbs. But there is a fungal component too which DMSO will help kill off.
Consider the possibility of a low-grade histamine reaction or related mast cell activation MCAS. My scalp itched for years until I accidentally discovered MCAS was happening. Quercetin made the difference.
I do have MCAS and take a number of things for it (quercetin, perimine, etc.) Chat GPT just went through my supplement list and suggested ones to take out that might aggravate mast cells. But I will say this scalp thing came on instantly and has been constant for 3 months. Different than most MCAS which comes and goes.
I did early on. Also lemon juice, olive oil, salt scrubs, etc. Nothing worked. I was pretty convinced it was a fungus and my doctor gave me prescription antifungal shampoo. Which seemed to work at first but then made it worse over time. Now I've gone back to organic products with anti-inflammatory ingredients, also experimenting with DMSO and silver, and with essential oils. Hydrocortisone cream works. But I have very thick hair and it's really hard to get product onto my scalp instead of in my hair.
Have you tried high dose biotin? If it's seb dermatitis it could cure it. 40 mg (not mcg) for three months, then decrease dose for maintenance. Completely nontoxic, they give 200 mg to babies.
Following this thread as my son has been struggling for two years with a very stubborn scalp issue. I suspect folliculitis, but rhe doctor said the culture came back negative. It almost resolved after a round of antibiotics for another issue he had, but it returned in force. I've tried homeopathy, ACV, colloidal silver, changing to all organic shampoo, honey. I sent him to camp 2 weeks ago with a spray bottle of 50% DMSO combined with Lugols and colloidal silver. I hope he has had some success with it!
Try liquid coconut oil, rub into scalp, leave for an hour or so, wash out. Don't heat up solid coconut oil to get a liquid because it will re-solidify in your drains. Do every 2 or 3 weeks. A very soothing and healing natural scalp treatment is here: https://www.youtube.com/watch?v=jTI8ki67BK8
I need to know if DMSO is contraindicated for someone on blood thinners, specifically Eliquis. My 89 y.o. dad wants to use DMSO for various things, but I'm afraid to recommend it until I can answer that question. If the answer is nuanced we'd find a doctor for a personal consult but then...where to find such a doctor who would have the...authority, audacity...whatever, to find an alternative to Eliquis (if that's what was needed to be able to take advantage of DMSO)?
The observation within the DMSO community and the doctors I know is that it is not.
However, I have read 2-3 reports from readers who said they started having periodic nose bleeds on DMSO. Given all of this, the most prudent course is to start with a lower dose, monitor coagulation parameters (which is often done for anticoagulants anyways) and then gradually raise the DMSO dose.
Why is he on it? DMSO has anticoagulant properties and it could potentiate the Apixiban, however DMSO works on many fundamental issues that cause the need for blood thinners. Would have to be done very carefully. AMD has shed light on some of these issues, which may be correctable, specifically blood sludging, zeta potential and arrhythmias.
Yes, very good. So, he's got a history of a-fib, which I don't know if that is considered cured or not, now that he has a pacemaker. But the reason they keep him on the Eliquis now is because of his heart valve clip which is supposed to reduce some of the excessive backflow. Supposedly that device can generate clots. The "very carefully" part is why I would much prefer to find someone we can consult with who has a complete understanding of all the issues involved, as well as the...whatever it takes to go against what I would assume to be the conventional wisdom, or standard of practice, that the blood thinners (especially the ones that make someone some money) are what are keeping him from stroking out. Plus, as you might see, my own cynicism of conventional medicine is going to keep me from seeing things clearly as well. I've just been reading so much evidence of misconduct and deception there lately, that I'm almost inclined to do exactly the opposite of what they say is the truth, assuming THAT must be the truth. And then along comes DMSO (again, I suppose) and I'm maybe TOO ready to trust it as a cure-all.
PS: I agree, the medical system is nearly complete bullshit. And I was skeptical of DMSO at first. That is until I tried it on myself, my wife and then my patients with amazing results.
So, not cured, but managed afib. He's on the Apixaban due to the risk of a thrombous, both from the fib and the clip. The clip you referred to is typically treated with 6-12 months of aspirin and plavix. Unless the interventionalist does Apixaban for unique clinical insight (cards is probably viewing this like an artificial valve which stimulate clotting). To my knowledge, I am not aware of an interaction with topical DMSO and Apixaban. The same is true with oral MSM which is the processed version of DMSO (essentially). Although there aren't a lot of docs out there using DMSO, let me know where you live and I might be able to put you in touch with someone. At your dad's age, regardless of weight or renal function, if he were my patient, I'd have him on 2.5mg Apixaban twice daily and if he wanted to use it orally, I'd check an anti-Xa lab exactly 4 hours after his first dose of the day. Not much you can do about the clip, but it makes sense to read up on Zeta potential and try to find a doc well versed in these approaches.
Me Jane, I just found out last week that my D.O. got DMSO in for IV's. Gonino Center for Healing, Heath, TX. Maybe this will help you, I don't have anymore info other than the fact he has it and is using it with his patients.
To be more precise, I really just want to give this field the best shot it has to succeed and become something people regularly do, so I want to give it a really good start to grow/sprout from, which meant I couldn't cut any corners on it. I also find all of this absolutely fascinating which is why I tried to track down every single thing in existence about it.
I would like to print it to save my poor eyes - i can't look at the screen too long. But I'm finding it almost impossible to do. Could you tell me please how you managed to print the article? Thank you.
I have a hemifacial twitch (for the last 10 years) that has spread from the right eye to the nasal labia area and now the chin (seems to be the trigeminal nerve). I have tried many natural treatments from Acupuncture, Chiropractic. and massage without much success. I currently have been using botox around my eye to slow the twitching (particularly bad when I lay down and try and sleep) but cannot use it in my chin. The neurologist wanted to do brain surgery as they thought they saw a nerve that was caught on the edge of a bone, but I will not consider that nor medications like Gabapentin. Is it your opinion DMSO could help and if so, what protocol would I use?
Hi Elaine, I decided to take 1 tsp of 75% DMSO internally to see if it can help. I have only taken it for 5 days and have already seen a positive reaction to my arthritis in my knees and hips and a slight slowing of the twitching in my chin area. I still have heavy Botox in my eye area so I can’t tell yet. I won’t know until the current Botox wears off but the other improvements are so welcomed!
Shelly, I haven't tried that. I do have botox but it only helps a little bit. It's hard to find someone that's really good without looking weird! Are you a member of the Hemifacial spasms group on FB? According to them the only cure is surgery, but not always. I'm 80 so not sure if want to go thru that. If it's a nerve that's compressed I'm not sure how DMSO will help.
Hi Elaine, I am 70 years old and will not do the surgery. I do not do Facebook so am not part of that group. DMSO has proven to regenerate cells and reconnect neuropathways so I am willing to try and see...if it doesn't help, nothing has been lost and it is definitely helping my arthritis, so if that is possible (knees were bone on bone at last xray) then who knows what it can do for the hemifacial twitch. I have also seen DMSO heal wounds very quickly so if the nerve covering has disappeared due to the compression, perhaps it could help that...don't really know but I am willing to wait it out for a bit. Good luck and I will keep you informed if it does help!
Thanks Shelley. Just wondering - do you smell like garlic from taking it? I'm going to try it. Also, I think the nerve is compressed and that is why it's twitching. Then, ultimately the covering wears away. I'm on that list just to obtain info and experiences of other people. Not all opt for surgery as it's a serious one. I mainly just read.
Thank you once again for all your work on this topic! A combo I've been using, just because it made sense to me to try, is DMSO and Dr. Christopher's Bone & Tissue ointment. The later I've been using for much of my life to heal everything from skin wounds to broken bones. It's a salve with comfrey and other herbs. Adding DMSO by just applying some to the skin area I'm working on, and then rubbing the Bone & Tissue into the same area seems to increase it's effectiveness. As in skin heals even faster than I have been used to over the years using the same salve. I've used anything from 20% to 100% DMSO for this depending on if applying to something more sensitive like the face or less sensitive like the legs/feet. The Bone & Tissue salve also seems to counter any tingly/burny feeling the DMSO can create by it's self as I will feel that if using only DMSO, but not at all if applying the salve immediately afterwards.
I've also had the same experience combining it with other herbs like a calendula hydrosol. If applying DMSO to my face (in a 20% solution) I can still get some tingling that's not bad, but not really comfortable. But if I mist the hydrosol over the skin right after applying DMSO, that doesn't happen at all. I assume it also might help increase the skin benefits of calendula but I can't say I have anything measurable to report on that.
Dearest Midwestern Doc, I have a son who was in the Marines, he has chronic back pain and migraines, and developed Type 1 Diabetes at 27 years old. Nothing has helped him. I told him about DMSO and he read that it’s a problem for Type 1 diabetics. Can you advise what kind of complications and if he should avoid trying DMSO without medical supervision?
Thank you for the great article. I have been trying DMSO for a while to help with general well being.
Some experiences:
I struggle with fatigue/burnout and often feel my the back of my neck area tenses up easily. I have had some success by putting DMSO on that area, feeling that some "flow" is returned. My inspiration for this was from other articles where you mentioned the vagus nerve often getting compressed around here and the need for good circulation to and from the head, not least for sleep.
I also had the idea to put DMSO around the kidney/adrenal area on the back (very roughly), to see if it somehow could help support the adrenals. Sometimes I can feel like a constriction in them when overexerted or stressed. Perhaps the DMSO helps create flow around here too, because it does seem to have some effect and I haven't felt that constriction as much afterwards.
So overall some good effects. Had effects wane a little after a while, but trying to find the right amounts and ways for me.
Questions:
The only downside seems to be body odor. I don't notice it myself, but others complain. Seems to kick in fast and last pretty long for me, at least if I try to take it orally. Are there any ways to mitigate it?
Other things that have helped me are lithium orotate and KSM66, to name a few.
After reading this article I'm very interested in trying DMSO combinations. I just wonder about mixing things. Let's say you have a supplement you'd like to try with DMSO - can you empty capsules in concentrated DMSO at let it sit for a while, then dilute it to say 50-70%? After that apply it topically? Guess I'm wondering about how much to use of each when making a mixture.
I have used methylene blue at 15 mg per day to restore my immune system after it was crushed by the Johnson & Johnson COVID-19 vaccine. This process took about 3 1/2 months. That was a in 2021. I have been taking methylene blue at the same dosage every day since that time. Recently,thanks to the posts A Midwestern Doctor, Recently,I have been drinking 3/4 of an ounce of 99.995% pure DMSO liquid along with the methylene blue. The result is that very little methylene blue appears in my urine! I believe this is because the DMSO is helping methylene blue penetrate my body’s cells more efficiently!
I've been experimenting with DMSO for a full year now. Mostly topical application. I started with 1:1 mix of DMSO in high-quality olive oil, gradually worked up to 5:1. It knocks out muscle pain and bruising like magic.
The most striking result was a hip joint that was steadily becoming more painful - I was considering asking for surgery. (I'm 70.) I applied the DMSO-oil stuff 2x day for a couple of months, then also started eating collagen powder with my breakfast (5 g day). After 6 months, no more pain at all, just a hint of stiffness after sitting for a long time. So I've gone down to 2x week (still taking the collagen every day). Pretty cool experiment!
I'm also using it for varicose veins, and after a year of 2x day (with one day a week off), they are only slightly improved. But considering I've had this condition for 50 years (!), I'm prepared to be patient. Oddly, I've noticed that the progress comes in waves, and the 1-day break seems to contribute to that, not sure why.
More recently, I've started trying to cure my chronic rhinitis by swabbing it 1x day in my nostrils and soft palate (so that it trickles down my throat). I put up with a brief burning in my nose, and an awful taste, but it seems to be working.
I thought I was being adventurous, but this article has so many more options I see I've barely scratched the surface!
PS - forgot to mention, this mixture also cured a TMJ problem that was deteriorating. This was originally why I first bought the DMSO.
And I do mean "cured" - my jaw went from a painful locking habit on one side (often while I was asleep - very disturbing!), and pain when biting into food, to totally normal functioning again.
That took around 6 months, applying the DMSO 2x day to the joint and along the neck tendon near it (behind the ear). Somehow they seemed to work together.
I have been fascinated by your posts and I'm delighted to tell you that the last three weeks I have been using 50-50 99% DMSO with normal saline with 12% magnesium chloride in a nebuliser for five minutes each day. The results have been spectacular and I have stopped using my Ventolin puffer which I was using up to 12 times a day. It is really an extraordinary result. As a physiotherapist I am gobsmacked. I would like to include glutathione but my compounding chemist is unwilling to suggest a dosage to be added to my combination above. Can you please suggest one, for which I would be eternally grateful
Maybe I’ve overlooked this information, but how often is dmso used? I just got a 70/30 to start and used it the first time yesterday. Stiff neck and low back pain are definitely improved. Applied again this moving I still have soreness even though overall better, but how much is too much? I don’t want to go overboard, but honestly, this is the best I’ve felt without nsaids for years. Is twice a day normal?
Thank you so much for your reply. And thank you for all the work you are doing with this Substack. You are truly changing lives. God bless you, Doctor.
I used essential oils of turmeric and frankincense one drop each combined with DMSO gel when I started treating my knee inflammation and swelling (from old ski injuries and minescectomy) with excellent and fast results, after your first series of articles on DMSO.
This has opened the floodgates of my imagination for a number of future combinations to try.
It has been mentioned that DMSO can treat nerve pain. From a hip osteotomy in 1984 the femoral artery was ruptured and pressed on femoral nerve. Artery repaired but left me with severe pain/injury of the nerve. I have not so good circulation in my leg all this time later with still some nerve pain. How best to treat this with DMSO? I posed the question in the comments earlier about taking DMSO internally with hip implants. Will this cause complications?
I have another question on DMSO. My brother has some kind of severe fibrosis in his lungs. Can barely walk to the mailbox. I saw the video of the guy with COPD that put DMSO in his inhaler SOMEHOW. But it doesn't describe exactly how to do it. Does anyone know exactly what the procedure is for this? Like, HOW do you do it?
I'm reading the comments and the article, but my problem is finding exactly how to mix things. I have a rotator cuff problem in my left shoulder (already had surgery on the right shoulder). I'm mixing 50% DMSO and 50% magnesium oil, put it on the shoulder every night. Seems to be helping a little. I'm reading here about MSM / DMSO. How about just putting a glucosamine/chondroitin/MSM pill contents into the mixture? OR I could buy bulk supplements MSM powder.
Has anyone here experimented with combining DMSO with peptides? For example BPC-157 is on the upper edge of the size DMSO should be able to transport through the skin. I am thinking about topical DMSO/ peptide combinations as an alternative to subcutaneous injections.
I just saw a company that is marketing a sports recovery cream that contains DMSO, BPC 157, TB 500 and MSM in organic aloe vera gel. Interesting to see people formulating.
Hi! First of all thank you so much for this. Thanks to you, I’ve been using DMSO to shrink large varicose veins on my legs - while they’re still present, they’re much smaller, softer, and a sensation of “thickness” that was present before is no longer there! I’ll share a before and after once they’re gone or almost gone.
A few questions for you. Do you see any potential benefits or detriments to taking DMSO orally while doing an extended water fast (eg 48-72 hours)? My initial thinking is it would help with healing while the body has more capacity from having a break from demanding metabolic activities from digesting.
When measuring out DMSO for oral consumption, is it ok to use stainless steel measuring spoons? I’m fairly paranoid about inadvertently getting anything harmful into my system from all the warnings.
For applying herbs and roots (eg ginger and turmeric), would you recommend using a powder, juicing fresh roots, or buying a tincture with an extract ?
1) It's advised to take beforehand, not sure if it's good bad or neutral during the fast. My guess would be if you are less sensitive, it's good (bc you will do a deeper detox) whereas if you are more sensitive, its too much).
2) Yes that's fine.
3) DMSO will extract the herb, so you can mix a fresh herb or a powder with it and let it soak for a day.
Definitely agree that this is the most comprehensive article yet! Thank you very much for aal that you do and contribute AMD! I was wondering about the following. In March of this year I underwent stem cell therapy on both my knees for osteoarthritis Grade IV. So far, it has worked wonders, i can walk stars without any pain and can go on a brisk walk of 1 hour on flat, frim terrain. Every night I have been rubbing Andiroba and its sister oil Copaiba on them, and it seems to be enhancing the work the stem cells have been doing, lessening inflammation and promoting cartilage healing. I was wondering, haven't experimented yet, if applying a layer of 70% DMSO on top of the oil blend would be safe. Would you please be able to give some advice on this? Much appreciated, many thanks. L.C.
I am curious since DMSO is also a substance transporter, is it best used with purified water and on an empty stomach? I realize the article says 1 tsp with water slowly after a meal but what if any toxins in the food such as hormones or antibiotics in meat or glyphosate from farms? Am I overly concerned?
Overly concerned, but good thinking. Its wise to consider this. I probably wouldn't want Mcdonald's running rampant through my system, potentiated by DMSO.
Also, my husband has chronic sinus infection... he uses a nasal spray daily. Is DMSO something that could help here? He would like to be less dependent on that spray...
When I had a sinus infection I rubbed it directly onto my face. It was 100% strength and it did leave me with skin irritation but my sinus pain was gone in minutes.
Some folks find relief with a 10-20% DMSO solution first, followed by CDS and/or glutathione, netipots, xylitol. Some suggest ozone held in the sinuses.
Same here. Problem is how to get medication way up into the sinus labyrinth. I use a nebulizer that atomizes the medication, still not sure it goes all the way into the sinus parts.
Doc writes in this article..."when drinking H2O2 use 10-20 drops of 3% in a glass of water with DMSO". Use 1-2 times/day AWAY from meals ( 30 minutes before or 3 hours after meals).
"DMSO: A Mixed-Competitive Inhibitor of Human Acetylcholinesterase"
The above is the title of a PubMed study. I wanted to ask if this means that DMSO has anticholinergic effects-- the same as anticholinergic drugs that older people are cautioned against taking because of possible cognitive downsides, i.e., on memory and risk of dementia.
Any recommendations for dmso mixture for mother in law with resistant infection after knee replacement surgery that didn't go well? She's 82.5 years old, in incredible pain and the doctor's haven't been able to rid of the infection even after a second surgery to help "clean out" the knee and infection!
Due to the "advanced" medicine in my home country of Macedonia and my weight at the time, no doctor took an X-ray, let alone a CT scan.
In the end, I got an X-ray on my own, and the result was emphysema. Officially, I was told there’s no help for me, so I started looking into unofficial options to see what’s out there.
I engaged GROK from X, and it started finding some things.
To keep it short, I’ll write what I’ve been using with no effect—maybe I’m not dosing correctly.
If anyone wants to help, please do, because I’m at the end of my rope. I nebulize 3 ml of DMSO (50/50 ratio) twice a day.
I nebulize 1 ml of liposomal glutathione (containing 55 mg glutathione) twice a day.
I nebulize 15-20 drops of propolis once a day.
And sometimes I nebulize 3% hydrogen peroxide diluted in a 2 ml hydrogen to 10 ml water ratio.
Due to the "advanced" medicine in my home country of Macedonia and my weight at the time, no doctor took an X-ray, let alone a CT scan.
In the end, I got an X-ray on my own, and the result was emphysema. Officially, I was told there’s no help for me, so I started looking into unofficial options to see what’s out there.
I engaged GROK from X, and it started finding some things.
To keep it short, I’ll write what I’ve been using with no effect—maybe I’m not dosing correctly.
If anyone wants to help, please do, because I’m at the end of my rope. I nebulize 3 ml of DMSO (50/50 ratio) twice a day.
I nebulize 1 ml of liposomal glutathione (containing 55 mg glutathione) twice a day.
I nebulize 15-20 drops of propolis once a day.
And sometimes I nebulize 3% hydrogen peroxide diluted in a 2 ml hydrogen to 10 ml water ratio.
I started reading the DMSO articles in 2024. I purchased some from the DMSO Store and have had a couple experiences using it. While nursing I got mastitis, and it didn’t work topically. I had to resort to antibiotics, unfortunately. However, I did use it to effectively eliminate an inflamed alopecia spot on my scalp. First time with full hair regrowth without the use of injected kenalog!
For using in the eyes it says 3% isotonic solution. Does that mean 3% dmso mixed with the rest being normal saline? Not sure how to achieve this 3% solution. Could someone please help me?
I really appreciate the amount of detailed information here! I'm just learning about DMSO and this is super helpful! Any information on using DMSO to heal (or shrink) uterine fibroid?
Hi, I have just subscribed, live in the UK. The DMSO products recommended via links are not available to me due to location. Can you advise me of any UK suppliers that are reputable please?
I notice that you recommend Medicine Girl's substack. She seems to be against DMSO-she has an article "Disasterous DMSO" on her substack. Do you have any comment on her stand against DMSO?
Where did I recommend her (if I am I would like to cancel it)? I think her info is highly erroneous. She essentially posts that every natural therapy people benefit from is deadly poison, attacks everyone who supports them as a pharmaceutical lackey, and then posts a lot of erroneous and incomplete information to justify her position.
We've tried to reason with her on a few topics and concluded she was either refusing to change her position because she wants traffic by creating controversy or because she is being paid off to torch off-patent therapies (I lean to the former, a lot of others lean to the latter).
Regarding her stance on DMSO, it fits the pattern of what she's done an other therapies. Most of the article was incorrect or extremely misleading, she refused to correct anything when given information (either now or on previous versions of it) and while most of the commenters had very positive experiences and no issues, she told all of them their experiences for one reason or another didn't count.
I hope someone can help me. I am having an allergic reaction to a combination I used and nothing I try helps the hives and intense itching.
Day 1: I fell and twisted my ankle and left knee very badly, also strained my right knee (I have arthritis in both knees.) I rubbed the foot, ankle, leg, and knee with Herbal Mana Frankincense DMSO Gel, and also rubbed the right leg and knee. I was amazed to get relief. I continued that protocol morning and evening until Day 3. On Day 3, there was significant bruising and swelling on the left foot, although no pain, just mild soreness. On the evening of Day 3, I showered, and applied Arnicare Cream, waited 10-15 minutes, and applied the Herbal Mana gel on top of it.
By the evening of Day 4, I developed hives and itching on both legs where I had applied the Arnica Cream and Herbal Mana Frankincense DMSO Gel. Benadryl gave me no relief. I started Zyrtec and Pepsid. Also 1 gram of Vitamin C every 2-3 hours.
Days 5-10: The whelps and rash were only on the areas where the cream/gel were applied and did begin to diminish, but the intense itching did not. I've used aloe vera gel from a plant, benadryl cream, cortisone cream, witch hazel, coconut oil (not all at the same time). Nothing has given any relief.
Day 11: Whelps began to appear on the upper abdomen and inside lower arms, then around my neck and chin. Itching is intense. Had taken Zyrtec in the am, took 50 mg Benadryl at bedtime. No relief.
Day 12 (today): This morning, whelps are developing on my face.
I have been afraid to use DMSO again, although I feel that the culprit must have been the inactive ingredients in the Arnica cream. I do have a bottle of DMSO pure pharma grade 99.995% from the DMSOSTORE and have gotten distilled water. Would I dare try drinking a weak dilution or rubbing it on the hives?
I am able to walk without pain, although the left foot and ankle are still swollen and may be bruised under the red rash.
What you are describing sounds like you had an allergic reaction to arnica (which is known to happen to some people) and DMSO may have enhanced that by bringing it into the body.
Main priority is to completely avoid any arnica products, stop the topical things, and to be on the watch for if it seems like the allergic reaction is spreading to the throat (as at that point, you will need steroids to prevent an anaphylactic reaction). Given that it's spread to your face, that is a possibility, so I would try to see a doctor as soon as you can rather than once you start to notice swelling around your throat.
There are a variety of home remedies which can help with the itching (ie. standard process Antronex, cooling the affected areas), but I would advise seeking out medical help to avoid the risk of anaphylaxis.
I hope someone can help me. I am having an allergic reaction to a combination I used and nothing I try helps the hives and intense itching.
Day 1: I fell and twisted my ankle and left knee very badly, also strained my right knee (I have arthritis in both knees.) I rubbed the foot, ankle, leg, and knee with Herbal Mana Frankincense DMSO Gel, and also rubbed the right leg and knee. I was amazed to get relief. I continued that protocol morning and evening until Day 3. On Day 3, there was significant bruising and swelling on the left foot, although no pain, just mild soreness. On the evening of Day 3, I showered, and applied Arnicare Cream, waited 10-15 minutes, and applied the Herbal Mana gel on top of it.
By the evening of Day 4, I developed hives and itching on both legs where I had applied the Arnica Cream and Herbal Mana Frankincense DMSO Gel. Benadryl gave me no relief. I started Zyrtec and Pepsid. Also 1 gram of Vitamin C every 2-3 hours.
Days 5-10: The whelps and rash were only on the areas where the cream/gel were applied and did begin to diminish, but the intense itching did not. I've used aloe vera gel from a plant, benadryl cream, cortisone cream, witch hazel, coconut oil (not all at the same time). Nothing has given any relief.
Day 11: Whelps began to appear on the upper abdomen and inside lower arms, then around my neck and chin. Itching is intense. Had taken Zyrtec in the am, took 50 mg Benadryl at bedtime. No relief.
Day 12 (today): This morning, whelps are developing on my face.
I have been afraid to use DMSO again, although I feel that the culprit must have been the inactive ingredients in the Arnica cream. I do have a bottle of DMSO pure pharma grade 99.995% from the DMSOSTORE and have gotten distilled water. Would I dare try drinking a weak dilution or rubbing it on the hives?
I am able to walk without pain in the left foot and ankle, although it is still swollen and I suppose bruised (the red from the hives/rash covers the bruise.)
Thank you for all your research and time. You are a gift to us all 🙏
I do have a question that I have not come across an answer for yet.... can DMSO be ingested or even applied topically if I have an implant, or a metal screw or a plastic mirena etc??
Doc, you and Dr. Mercola have expounded on the many uses of DMSO and I was impressed enough to buy some; however, I read another SUBSTACK article explaining that DMSO is a waste product of the paper industry and a solvent. The MSDS lists it as a hazardous material. Can you address the possible risks of it? I want to be fully informed.
She keeps posting that to get traffic. It's highly inaccurate, but each time we try to explain (along with dozens of readers who have tried as well) the specific points, she says we are brainwashed by the medical field and don't understand what we are talking about since anything else cost her views and refuses to correct anything (along with telling everyone who says DMSO helped them a lot and had no side effect that their experience, for one reason or another, doesn't count).
Her brand essentially is saying commonly used natural therapies are actually toxic and you need to just do detoxs and elimination diets. When I looked at her arguments, I realized that she was juxtaposing common issues with other pharmaceuticals onto DMSO (which is a common thing people do, as due to it being hard to fully understand a subject, they always juxtapose their pre-existing knowledge base onto it).
Regarding the deaths, the points she's omitting is that in all but one of them, another product was involved, as on FAERS if someone has a lethal reaction to a drug, they list all the other things they were taking as well, and in those cases, it was more likely culprit of death, and in many cases, they were being given intravenously (where a higher risk of death, particularly the onyx cases where the DMSO polymer mixture was being used to patch an otherwise fatal internal bleed and hence was a high risk situation). When I wrote the safety article, amongst other things I read through all the FAERS reports and explained them, no one else has done that. Conversely, most medications have thousands of deaths in FAERS, many of which can be directly attributed to the drug. The fact that over roughly 40 years 21 deaths are in there almost none of which can be attributed to DMSO is an insane safety profile. The primary drug DMSO replaces (NSAIDS like ibuprofen) are well recognized to kill hundreds of people each day, and their toxicity is rarely discussed.
In short read these two article, critically compare them to hers and then make your own decision:
Thank you for this amazing resource! This will help so many people.
I would like to try DMSO as an eye treatment and experiment to see if it can reverse presbyopia.
Has anyone used DMSO in their eyes after Lasik surgery? I had Lasik surgery about 15 years ago and was curious if I can still use DMSO eyedrops in my eyes (diluted of course).
I'm intrigued with the possibility of combining DMSO with laetrile. An on-line search suggested that the maximum safe dose of laetrile is .37 mg/kg body weight. I weigh 73.5 kg, so using this formula my max safe dose is about 27 mg. One can buy derivatives of apricot seed capsules on-line, but they typically contain 500 mg of apricot extract. How would one reconcile this?
Berberine has been shown to be an incredible cancer therapy targeting multiple pathways. But bioavailability is challenging. Could it work with DMSO, perhaps topically?
Hi! Back is now essentially pain free after about 2 months of regular use. Was using a 70/30 DMSO and aloe vera gel mixture on hip, si joint and hamstring injury. Was using with magnesium oil, peppermint, lidocaine cream, & arnica. More recently, an 80% solution with peppermint oil has also been great and it dries much faster than the two with no residue. However, we are finding that my clothes are carrying the scent after laundering. I usually try to make sure I'm dry before putting on clothes but am wondering if there is a residue causing the issue. What detergents are working for others to get rid of the smell? My husband is complaining and I don't want to give up my pain relief!
An idea: Vinegar is very good to remove residues, and as a presoak.
Fill washer with water, hypoallergenic laundry soap, 1-2 cups vinegar (5% acetic acid), let soak for a while, 15-30 minutes. run wash cycle. When filling for rinse add 1-2 cups vinegar. I run 2nd rinse cycle, add 1-2 cups vinegar, done.
I can't help but wonder if Dr. Mercola and the "Midwestern Doctor" aren't one and the same. I'd been suffering from "arthritis" in left hip. From my reading, DMSO doesn't seem to be reliably effective in the case of that large joint or much of anything below the waist. But. I've been applying DMSO full strength in addition to physical therapy and feel like I've gotten some relief! At least one of my children tell me that the "placebo effect" can be quite powerfull. Whatever!
I wish I could make more of a commitment than "monthly" I'd begun following Dr. Mercola at end of 2019. I was particularly enhusiastic about his insights after he was on the Governments short list of disinformation providers. I fell out while he continued to speak in terms of viruses. I read Virus Mania in 2020. I also support Westin Price and the Baileys. I think it must be difficult when one is in business as Dr. Mercola clearly is to change one's position on "Germ Theory." This is why , I can't help but wonder if Joseph isn't "The Midwestern Doctor" I guess this would be like unmasking "Batman." I folowed the "Root Cause Protocol" after being introduced to it by Dr. Mercola; until
looking into their un supported suggestion to look into bio magnetism. Ied me to study it and found the diagnosis revolved around treatment of various named "virus" and "parasites" I am on board with magnetic therapies to the extent that thay encourage blood oxygenation and thus ph and resulting blood alkalinity. Too much to say here! I also appreciate Mercola's advice on EMF exposure and am a longtime student of Victor Schauberg and structured water. Bravo!
In my case, without any prior knowledge of this wonderful paper, yet with some input from the ongoing stream of useful papers from AMD, I have followed the discovery of Dr Paul Makis, the discoverer of his 80% successful cure for Sepsis, intravenous vitamin C combined with Thiamine, (vitamin B1) and hydrocortisone, I had already made a solution of 50% DMSO with distilled water, and then added 100g of vitamin C, later increased to 200g, and then as I had a small quantity, 10g, of Vitamin B1, I added that as well. The use of which has produced some very interesting results. As of now the bottle has to be shaken to distribute the contents, and I am going to continue to take a teaspoon every day diluted in a glass of water.
Again, having also discovered the video conversation; Dr Adis - The Antidote, I am already using Nicotine patches, but now wonder if the addition of a similar dose of Nicotine would make the nicotine patches redundant. There are so many possibilities, and we can be sure that a new industry will arise from our expeditions into the associated original thought progress.
DMSO use having had replacement lenses fitted to treat cataracts. Would topical, nebuliser or systemic use affect the plastic lenses? I have auto immune issues I’m trying to treat.
Can anyone please tell me where I can purchase DMSO that is pharmaceutical grade enough for nebulizer and oral routes? I’ve heard most of it listed on Amazon is junk. Thank you.
I'll ask here, and if not seen or nobody able to answer, will post again on the next article on DMSO. Thanks. Evidently the clots from the shot do not break down enough and would not show up on a D-dimer test. Three questions please: other than live blood analysis (if that does show the clots), and an esoteric TEG test, how would one know that they are in the body? How to break them down (is Nattokinase effective)? And will applying DMSO to the carotids still work for someone who has a stroke from a spiked clot??? Thank you AMD and/or to whomever can answer.
I am recommending Neprinol AFD to friends who have had strokes. (and to anyone who will listen) Is it accurate to say that regular anticoagulants and tPa do not break down spike induced clots???
Where is there info on using dmso for pets, specifically cats? My cat just developed asthma and I understand it's great for humans. What about cats? He's an 18 lb mixed Maine Coon and he won't take anything orally. Clipping his nails takes two strong people, lol! Thank you!
You mention the use of Prostatilen for treatment of BPH. Where can I get the 30 mg one that you recommended from? Is there anyone out there who has used this and has some experience?
I cannot thank you enough for your incredible research. A good friend who has suffered for decades with an autoimmune condition finally relented a few months ago and is now on Enbrel and Methotrexate. Would she need to stop these drugs before trying DMSO? I've seen your research that DMSO can be used diluted on its own or in combination as an efficacy enhancement with lesser doses of other drugs, so I'm not sure how to help her navigate this. It's so difficult when the doctors and specialists have no clue (and don't want to have a clue!) about DMSO.
In the section on DMSO in Veterinary Practice specifically severe dermatitis involving feet and nail beds are there articles I can get links to. I’ve tried following the links in the references but it’s not getting me anywhere. I’ve just started the treatment this morning by mixing in equal parts DMSO + Nitrofurazone & Nystatin. I was hoping for more specifics from that particular reference of 9 cases. We’ve had very little improvement early on with typical vet treatments and his condition seems worse. When reading blogs people repeatedly saying the same that they try everything but no results. If there is any more information please share.
Doc, I understand that DMSO absorbs through all seven layers of the skin, and carries other substances with it into the bloodstream. My question is, does it penetrate the cell walls and enter the cells? I have very high serum B12, but low Intracellular B12. I have been searching for a way to get B12 into my blood cells. Can DMSO possibly be the answer?
I do have one coy of each (677, 1298) MTHFR genetic SNP. My father had pernicious anemia. I have neuropathy so severe that most of my body, including inside my mouth, are completely numb. I believe this is a B12 issue. Has anyone ever considered injecting DMSO? I am taking it internally, but it bothers my stomach somewhat.
In the book “The 85% Solution: MTHFR is Overpowering Our Medical System- - Chances Are, You Have It Too”, by Dan Purser MD, in chapter 3, it states:
“You can become toxic with high folate or high B12 levels, i.e. your body will have problems converting inactive forms of folate and B12 to the active forms. So the inactive folate or B12 will simply build up in your serum, also inhibiting the active forms.”
Your thoughts about this would be greatly appreciated
I just wanted to share my experience in support of this article.
For over a year, I dealt with what appeared to be eczema on the inside of my right ankle; about a two-inch square patch. The itching was relentless. It would keep me from falling asleep, wake me in the middle of the night, and drive me to scratch just to find some relief.
I tried everything: prescriptions, over-the-counter creams, and natural remedies. Nothing worked. No doctor I spoke to could offer a solution that made any real difference.
Then I found the undiluted DMSO roll-on from the DMSO Store. I applied it two or three times a day for about a month. The itching started to reduce, and after another month, the rash completely disappeared. The skin in that area looked a bit like a prune for a while, but the itch was gone!
I’m incredibly grateful. Thank you, Midwestern Doctor, for spreading this knowledge. DMSO changed my life.
I consider myself to be well-read on health but since finding 'aMD' via the Vigilant Fox. I am so humbled.
My experience with DMSO so far.
- ordered 70/30 (with Aloe) and had limited but positive results treating a damaged rotator cuff. I absolutely love the vivid dreams. Been using it over 1 week.
- ordered the liquid 99% and tried in my morning coffee with heavy cream, results an 'explosion' but I have no gall bladder.
- I moved to ~ 1 tsp with water and water as a chaser.. omg that stuff is really strong !!
- day 2 moved to 1 in the morning and 1 about noon.
- Edit: now doing only 1 tsp with water chaser.
I am noticing a big improvement with my shoulder. I am still going for an MRI to see if surgery is needed but based on my past 3-4 days I am thinking not.
My regiment is cream on my shoulder and 1 tsp/day. As 'aMD' has stated Everyone is different so start slowly and adjust. I am so thankful that I am in the 80% and pray for those in the 20% find a solution.
To close, in my experience with a clean diet and good health DMSO has been a very positive experience for me, I do not take any meds other than NP Thyroid.
I haven’t had time to read this article yet, but I saw something earlier today where they said I’d be very careful with DMSO because whatever contaminates, residue on your skin will absorb right into your bloodstream.
A dear friend has severe trigeminal neuralgia, as well as either the glossopharyngeal or vagus nerve neuralgia (it is extremely painful to swallow and it IS a cranial nerve). Because of the pain of these two nerves, and a lack of a good diagnoses (the trigeminal nerve problem was diagnosed but not the other nerve) she didn’t talk much at all and barely ate — because it was so painful. She ended up losing a lot of weight, and having a heart attack (the dr thinks it was because she wasn’t eating). After going to the hospital for the heart attack, a visiting neurologist was consulted, and this neurologist gave her the proper diagnosis, and she was prescribed two medications. She has to take the two medications, in higher doses to control the pain and be able to speak and eat. These medications (one of which is gabapentin) at the doses that control the pain, make her really tired, so that she only has a 1/2 day in her to do anything. This has effectively disabled her. I mentioned to her to read up on DMSO, and provided her with two of your articles (chronic pain and Injuries, and The FDA’s war against DMSO & America), and the only book I can find, DMSO Nature’s Healer. She said she was open to looking into using it after reading the articles & book and asked a nurse friend of hers about it. The nurse friend was (shockingly) excited and pro-DMSO, but, mentioned that since my friend has a heart stent, that DMSO and the heart stent do not mix, something about DMSO interfering with the stent (?). Does anyone know anything about this?
Amazing work! Thank you so much AMD. I've taken many good notes and will no doubt re-read this article many times. I've been experimenting - using DMSO on my knee along with MCT oil before walking makes the walk so much better. My hope is that the torn meniscus is somehow reforming. And if not, it feels like it is. Also starting to take internally and now... well now I have so many more things I want to try.
DMSO has been very helpful for me in dealing with several minor musculoskeletal issues over the past 8 months or so. It also seemed to have the effect of an increasing my overall general health…I seem to just simply feel better when I apply it. Feeling better to me has been even more valuable than the help with the musculoskeletal help even though they are probably one and the same. That being said, my wife and daughters complain about my odor. They say I smell like slightly sour milk. I have smelled this now and I agree that it is a bad smell. Any suggestions from anyone? Does this go away? Is it highlighting an underlying issue? Is there a way to mitigate it?
I would like to use this to help my husband who has both psoriatic arthritis (currently taking Cosentyx).Every joint in his body is hurting. In addition he has smoldering myeloma and anemia. I just don’t know how to use this to help him. I wish there were doctors around here that would help me learn to incorporate this into his care. I have a bottle on the shelf and have cut it with water 50/50 to rub on knees and feet. I never feel I know what I’m doing for sure. Any guidance appreciated.
Is DMSO safe for dogs? What wpuld be the recommended dilution for dental? My senior dog has had dental issues, gum disease, bad teeth. If safe I am considering diluting and try swabbing his gums.
I have been using topical DMSO for approximately 1yr now and tried the oral version this week. It seemed to do wonders for me by the 3rd day of taking it for my neck and back issues ( 2 tsp per day) but says I smell horrific. I have not had that issue with topical 70% DMSO and am wondering if there is any way to negate the odor I am emanating. My wife says I smell of creamed corn...lol...I can't smell it all on me. Any help would be appreciated because I had not felt as good as I did after a couple of days on DMSO in years.
Doctor, thank you for your wonderful help. Could an application of 70% plus 30% DMSO solution wiped over a 22 yr old friend's body beforehand be protective if he has a MRI (to ascertain if he has Multiple Sclerosis)? The 22 yr old has a sore back. There was a shadow on his back X-Ray and the doctor said he should have a MRI. Friends of mine became electrosensitive after MRIs with the dye, one friend does not recommend a MRI but the problem is the 22 year old wants a diagnosis (before going on a strict diet - the young sometimes hope to avoid such 'sacrifices'). I watched the documentary 'Living Proof' https://www.youtube.com/watch?v=Y56q_xkhSQg I wondered if a MRI without dye might still be able to show up CCSVI if it is there?
Thank you so much for these articles. Can you suggest a combination that you would recommend for Mast Cell Activation Syndrome in someone with MS , the MCAS observed as a consequence of to use a term “ The Elephant in the Room” that likely should not have been taken by someone with an Autoimmune Disorder. Currently the family member is using DMSO orally with Methylene blue and an improvement is observed with the brain fog aspect. But perhaps there is a better or different combination to avoid highly unpleasant and exhausting “ histamine dumps” as a consequence of any number of normal day to day activities including eating where it becomes a very bad idea to deny the body important food groups just to avoid these episodes. Any helpful suggestions gratefully received. Thank you for all your work.
I’ve heard you mention MSM as a byproduct of DMSO and some people are using it instead of DMSO. What is your experience with MSM and it’s effectiveness in these combinations? Is it possible to substitute MSM for DMSO in these remedies?My family cannot deal with the odour produced by DMSO so I am looking for alternatives.
Thank you so very much for all the hard work you’ve put into this series. Your efforts to get information about DMSO to the public is truly life-changing.
A few days before you published this article, I was trying to figure out how to manage pain from a strained hip muscle. Oral DMSO knocked it completely, but I don’t take it on work days due to the odor (my colleagues keep commenting that they “smell Onyx”). I tried hemp seed oil (purchased from Charles Warren Presents) with good relief, and 70% DMSO in aloe vera gel with better relief. I decided to try them together, and after 2 applications 12 hours apart, I had total pain relief. I applied the combination one more time after 12 hours for good measure, but have not needed it since. I didn’t notice hemp seed oil mentioned in your article so I thought I’d share my experience (though you do reference CBD).
Thank you again, from the bottom of my heart. I have made many lifestyle changes based on your articles and am feeling revitalized and rejuvenated at 60!
I have a question about how to use DMSO for my 17 year old son's acne. We have tried many things. Right now he is using a natural daily regimen which includes a rice flour scrub & topical herb based valves. I really want to help him. Where can I purchase DMSO? How should I administer to him? orally? Topically? What should I mix or dilute with? Thanks in advance for some instructions
A lot of this is from ~AMD, other sources and some from friends and relatives….
Purchasing Topical Ivermectin Cream In 1 of 2 Ways:
1. Doctor Rx Prescription for 1% cream...pharmacy filled & purchased after doctor visit or diagnosis.
2. Over-the-counter private purchase of 1.87% cream at any veterinary, pet, or farm supply store for immediate use. Most creams & pastes sell for under $10 & are ready for immediate use without a doctor visit, copay, or pharmacy visit.
DMSO (dimethyl sulfoxide) is a simple naturally occurring chemical
Ivermectin/DMSO Application:
1. Spray on a combination of DMSO & spread ivermectin on first then spray on DMSO(doesn’t matter which one, I would start with Ivermectin ) If needed lightly rub in with 1-2 fingers to the area needed. If you don’t need to spread it to the area needed just let it air dry. Use 30-70% DMSO, use lower for the face per user response… usually 2 -3 puffs of DMSO is enough to spread on the face.
2. Spray on 1-3x times daily, if dryness cut back, or use Aloe Vera for moisture or redness. Just wipe off and/o by wipe off with water around the eyes or other spots if tingling plus don’t get in your eyes, keep your eyes shut when spraying. Can also just put (rub on)more Aloe Vera on for tingling.
Spray on the forehead and cheeks, or only the problem areas….
Always clean your face & hands with organic soap, use only one or 1 2 clean fingers (because of the DMSO) to lightly spread and rub into the skin) Let air dry, and wait for 15-20 minutes before applying makeup, etc….
Rinse finger(s) off with water and wipe with a towel after spreading DMSO to the area needed, to keep the smell of DMSO to a minimum.
It may take several months with stubborn acne to see moderate results…..
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Other ACNE TXS
NOTE: Alternate various combinations best suited to your situation and what works best for you or the patient. Try different ones until you find one that works best.
The problem with most beauty products is that they strip the oil out of your skin. Each time your skin is robbed of oil, it compensates for the lack of moisture by producing more oil which leads to oily and inflamed skin that triggers acne. Don’t be afraid of applying oil to your skin. The essential fatty acids that castor oil contains help in restoring the skin’s natural moisture balance. Apply castor oil gently on your face and massage in circular motions. You can even leave it overnight and wash it off in the morning.
* 50% DMSO with Colloidal Silver is highly recommended for acne. Mix 40-50% DMSO with rose water or any floral distillate and Colloidal Silver in a clean glass jar. Apply using a natural cotton disk or ball to clean skin. For facial application, it’s best to use 50% DMSO or less till you see what you can tolerate. More is not better, start slow and increase.
* Hydrogen peroxide has also been used to enhance DMSO’s anti-aging properties. For the skin, it’s been reported to improve skin hydration and microcirculation when used topically, orally, or in a bath (where DMSO is applied to the skin beforehand rather than putting a lot into a bathtub). It also works quite well for acne (3% H₂O₂ followed by 30-50% DMSO sprayed on the affected area), blackheads, and pimples (apply 3% H₂O₂ followed by point applications of 70% DMSO).
Note: this combination is reported to clear acne much faster than conventional treatments, as it also addresses what is under the skin. An alternate regimen that has also worked quite well is 20-30% DMSO sprayed on, followed by CDS sprayed on, which is then allowed to dry (overnight causes a dramatic reduction in inflammatory papules and gradual clearing)~AMD
* Acne and Skin Lesions: A mix of 5% DMSO, 20% seawater, 3–5% urea, and aloe gel/almond oil (10:1) has addressed acne and neurodermitis. A gel with DMSO, lactic acid, urea, and seawater targets subsurface issues. Witch hazel is added for oily or acne-prone skin as a cleansing astringent. Note: For sensitive skin, limit DMSO to 10% and avoid synthetic hair products. Cleanse skin before application to prevent penetration of unwanted substances.~AMD
Hypochlorous acid is a completely non-irritating and incredibly potent antiseptic. It is naturally produced by white blood cells in the human body to help fight infections.
As such, I now use it instead of conventional antiseptics and for a variety of other things (e.g., when sprayed on the face with vitamin C, it’s often extremely helpful for acne). ~AMD
HOCl attacks invading pathogens, breaking down the cell walls before destroying unhealthy invaders. The antimicrobial acid is lethally effective in carrying out its protective mission. (Think of it as your own internal Batman.)
“It’s your body’s natural response to bacteria, and it is very effective at its job,” says Dr. Khetarpal.
* Fight bacteria that causes clogged pores and acne
* Speed up wound healing and repair damage
* Combat inflammation and conditions such as eczema or psoriasis
The best part, though? HOCl is nontoxic and handles this hard work while being incredibly mild on your skin. That gentleness is a byproduct of it being naturally produced by your body’s immune system.
“It’s great for sensitive skin,” notes Dr. Khetarpal. “It’s not going to give you the dryness, burning or irritation of other products [such as alcohol].”
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Possible Acne Treatments
Ozonated Glycerin
Hypochlorous acid and 10% OG solution: may also be combined and should work for acne
The benefits of Ozonated Glycerin are wide-ranging and impressive.
It has been shown to improve a variety of skin conditions including acne, eczema, psoriasis, age spots, irritated skin, herpes and shingles outbreaks, fungal infections, and even certain types of skin cancers.
As an antimicrobial, it offers powerful support for difficult-to-treat infections such as candida, Lyme disease, mycobacterium, and other resistant bacteria and protozoa.
In addition to fighting infections, it promotes wound healing, moisturizes and hydrates the skin, improves tone and elasticity, and supports overall detoxification.
Remarkably, it crosses the blood-brain barrier, making it a promising option for reducing neurological inflammation as well as systemic inflammation throughout the body.
It can even restore a sense of smell lost due to infection or injury, helping patients regain an important part of their quality of life.
Purchase online:
* PURO3…. Pure03 has OG available at wholesale prices for providers.
* OG is available from PURO3.com with discount code REDWOOD. I am told that PURO3 will be making their OG from our preferred glycerin source - organic USP glycerin derived from coconut oil. (I just completed a 1000 ml batch for office use. ORP is over 600 (excellent) and the peroxide test strip shows 5000 ppm, excellent according to Dr. Shiota’s teachings).~Rowen MD
Excellent! I have extremely severe Eczema on my face (that tracks perfectly with all my sinus passageways). My face looks like it was fried! Because of your writing, I started using 99.9% DMSO made into a cream for 70/30. IT IS THE ONLY THING THAT WIPES OUT THE ECZEMA! It has also taken care of an ankle/foot injury that was horrible (they are like new). I am just not sure when to cycle on and off. Keep up the great work!
researching using DMSO to treat forearm tendon pain that i believe is being caused by Seronegative Enthesitis. I want to try it with magnesium chloride or castor oil. I am hoping for some direction on finding a topical mag chloride product i can combine with DMSO.
I take 1.5T DMSO in a lime juice/water solution 4x/day. I have MS and am attempting to heal damage. It has been incredibly helpful for pain and energy. In May and June, separated by 2+ weeks I took 0.2mg/kg of IVM as part of an antiparasite protocol. In June and to a greater extent July my vision became a lot worse. Near vision contacts had been at -6.0 and went to -8.5. A full panel for thyroid, DM, and electrolytes were all normal so I was baffled but then read this article tonight. Could this have been due to this DMSO/IVM combination?
I also had another spot of melanoma come up on my leg (previous Mohs procedure on same legs 11/18 stage 1a) that I treated with chlorine dioxide and it seemed to improve until I had some skin breakdown. I stopped. It has healed. If it needs treatment again I’m going to use your advice and treat with DMSO and IVM topically.
Thank you so much for your work. I’ve been a reader since the first small pox article.
My MRI shows I have fluid in my hip joint and a torn labrum. My sports med doc wants to give me 2 PRP shots. First she wants to calm it down with a cortisone shot then do the PRP a month later. She said I can go straight to the PRP, but it could be extremely painful after for a week or two since it has not calmed down. I also have L5-S1 severe disc narrowing.(Aside: Patient derived stem cells are not legal in the US and I don't want to use umbilical cord ones.) DMSO Advice? MRI DX:
There is a small effusion with mod-severe osteoarthritic changes and grade 3-4 chondrosis. A non-displaced tear is present in the anterior superior labrum from 2:00-3:00. Mid bilateral common hamstrings tendinosis is present. There is mixed fatty atrophy and intramuscular edema in the adjacent quad fem muscles and can be seen with ischiofemoral impingement. Severe disc space narrowing and disc desiccation L5-S1.Deep acetabulum..can predispose to pincer type femoral acetabulum impingement. Also, how long should I stop doing DMSO before I get any shots?
My question — for which I’m yet to find the answer anywhere — is to do with the quantity of DMSO application and frequency, both with the drops and the gel, and is that different with various ailments.
Can anyone answer that with authority?
Perhaps The Midwestern Doctor can give us an idea, or point to a post to enlighten me.
Does oral dosing with DMSO reduce arterial plaque? I am unable to find a local physician who will administer it IV. I am 72 with familial hyperlipidemia and very high lipoprotein A levels. A carotid ultrasound revealed the presence of minimal arterial plaque. My cholesterol is 350 without drugs. Ezetimibe reduced it to 230. I have declined statins and Repatha as both are toxic and have serious adverse effects. I'm stumped on how to treat my familial hyperlipidemia, high lipoprotein A and carotid arterial plaque. My mother and maternal grandmother both had familial hyperlipidemia and died of strokes at age 90. Does oral DMSO decrease the arterial plaque, or at least mitigate further accumulation? If so, how should I dose it?
Does oral dosing with DMSO reduce arterial plaque? I am unable to find a local physician who will administer it IV. I am 72 with familial hyperlipidemia and very high lipoprotein A levels. A carotid ultrasound revealed the presence of minimal arterial plaque. My cholesterol is 350 without drugs. Ezetimibe reduced it to 230. I have declined statins and Repatha as both are toxic and have serious adverse effects. I'm stumped on how to treat my carotid arterial plaque. My mother and maternal grandmother both had familial hyperlipidemia and died of strokes at age 90. Does oral DMSO decrease the arterial plaque, or at least mitigate further accumulation? If so, how should I dose it?
Cyclodextrin pulls cholesterol (cell membrane, lipid droplet, crystalline, and oxycholesterol) out of the vessel wall, in a process that elaborates nitric oxide (vasodilatory and atheroprotective) and decreases release of inflammatory cytokines. Your symptoms begin to attenuate in 2-4 weeks (biochemical effects). With longer use, anatomic plaque regression can occur (as evidenced below). This molecule will save millions of lives, decrease our need for vascular procedures, and save billions of health care dollars.
Within our paradigm, that of Integrative Cardiology, the focus is risk factor reduction, not to directly reverse anatomic atherosclerosis, but rather to prevent plaque progression or plaque activation – and thus protect you from clinical events (heart attack, angina, and heart failure). Cyclodextrin will dissolve crystalline cholesterol as well as intracellular lipid droplet cholesterol.
Dr. James Roberts. Board-certified and university-trained in internal medicine and invasive cardiology, a Fellow of the American College of Cardiology, and has completed coursework and passed written exams in chelation therapy, oxidative medicine, bariatric medicine, and anti-aging and regenerative medicine, where he is considered an advanced fellow. Teaches the principles of integrative cardiology to physicians within integrative medicine training courses and have been involved in research on new drugs, devices, and nutraceuticals.
Right now, given the safety, low cost, and obvious efficacy of CD, my recommendation is:
1. In the setting of symptomatic atherosclerosis, 2-3 months of CD makes sense (or until symptoms resolve) followed by a maintenance program of 1-2 doses per week, with repeat 30-day programs once or twice a year.
2. In asymptomatic patients with moderate plaque (particularly if risk factor control is difficult) one month of CD twice a year can be used to make up for imperfections in our preventive program.
Keeping in mind that CD does not remove the underlying causes of atherosclerosis, ongoing risk factor reduction remains important, but with the benefits of CD, we may be able to cut back on the drugs which are most problematic to you. https://heartfixer.com/Cyclodextrin.htm#Coronary%20Artery%20Decalcification
Note: We can use change in carotid plaque and intima-media thickness (discussed elsewhere on this site) and coronary artery calcium score, as means of quantifying CD efficacy.
Very interesting...thank you. Would you recommend treatment with cyclodextrin for asymptomatic patients with familial hyperlipidemia and elevated lipoprotein A? Recent calcium score was 0 but ultrasound revealed the presence of carotid arterial plaque, albeit it minimal. The write-up you kindly provided focuses on cardiac events rather than cerebrovascular pathology causing stroke risk due to carotid arterial blockage which is the long-term concern.
MWD- I am very thankful for all your work, but in particular for this article, I am extremely interested in the Hydroxymethylfurfural (5-HMF) for CFS. One of my doctors thinks it's ME-CFS d/t the post exertional malaise and a few other symptoms. Anyways I'm desparate for some normalcy. I have already started mixing an oral solution of DMSO with honey it's supposed to have 5-HMF in it--but is it enough? Does this take a long time to take affect? I am already on selenium, boron, and magnesium, as well as other mitochondrial boosting supplements. I see the German supplement you have referenced, is this better?
Thanks in advance. I am always amazed at how you can put so many pieces of information into an article and tie them all together. Bless you.
I'm interested in any input regarding where/brands of DMSO people are purchasing.
I've been using DMSO store pharmaceutical grade 99.995% but I have found myself wondering about 99% veterinary grade from reputable sources. The obvious question is what is contained in in the .995% difference. An AI analysis indicates water is likely the most frequent impurity often comprising as mush a 1% of non DMSO content. Other possibilities Dimethyl Sulfide, Dimethyl Sulfone, Mercaptans, heavy metals, residual solvents or organic impurities (including acetone, ketones, acids, bases, halogen compounds-rare). If anyone has any educated input or experience using other then pharmaceutical grade I would appreciate the input.
I would also appreciate any input on healing shoulder injuries such as tears, impingement and bursitis. I’ve been researching formulations and have been using DMSO with magnesium and Castor Oil.
I was also wondering about creating mixtures using peptides such as BPC-157 (1419.54 g/mol) or GHK-Cu (~403 g/mol). Generally, molecular <500 g/mol is considered ideal for penetration but I’ve read anecdotal reports supporting trans-dermal delivery with DMSO for larger molecules. Does anyone have experience with using peptides with DMSO topically for healing these types of injuries?
Ive been using DMSO on my daughter for hidradenitis. I believe it has helped but maybe combo with something would help further. Does anyone have further suggestions on how to use for chronic skin condition HS. They are like boils that form tunnels under skin. She recently started drinking it but college starts and not sure she will be able to continue due to smell. Any suggestions would greatly be appreciated.
Over a year ago I had an infection in my collar bone. I applied Arnica, Comfrey compresses, and castor oil with little success. Then I applied DMSO, 92% plus 8% Aloe Vera, and within hours and a few days, I noticed the swelling going down, the pain subsiding and joint movement in my shoulder vastly improving. Within 6-8 weeks, between applying the DMSO and organic Castor oil at least 3-4 times daily, I was self healed. It was a truly amazing experience. This all began with me following you, my most favourite midwestern doctor, to realize the magic that is DMSO. My husband had a small but inflamed and painful lump in his left breast. The doctors wanted him to have a mammogram. Utterly ridiculous! Instead he started applying DMSO with Castor oil and yes, within 6-8 weeks of daily topical treatment, the lump diminished, the pain was gone and even without applying the treatment, it continues to shrink. I had 2 separate friends develop lumps below their earlobes. Infections it seemed. I bought them DMSO and castor oil and you guessed it. The lumps disappeared. My appreciation for your wealth of information, freely shared your research with us is beyond words. You have made our lives all the better because of your selfless efforts to make us aware of how we can heal ourselves. thank you.
Thank you! That's a big part of why I try to focus on specific areas and go deep enough into them to provide information that will really help people rather than superficially covering a lot of topics that get easy traffic.
I need some help here. My mother is taking corticosteroids for her autoimmunity disease (doctor diagnosed her condition as atypical lupus) and she's going to change the therapy now to Myfenax (mycophene motefil) But all these therapies have very bad side effects and already had a negative impact on her body.
Can you help me find an alternative cure? Reading AMD, I found that DMSO could help by diminishing side effects. But where can I find it here in Europe? What is the dose and how to apply it in her situation? I don't have any idea and we don't have here any doctor that knows about this kind of stuff.
Any info /advice you could provide of any kind, I would be enormously grateful to you🙏
I need some help here. My mother is taking corticosteroids for her immunity disease (doctor diagnosed her condition as atypical lupus) and she's going to change the therapy now to Myfenax (mycophene motefil) But all these therapies have very bad side effects and already had a negative impact on her body.
Can you help me find an alternative cure? Reading AMD, I found that DMSO could help by diminishing side effects. But where can I find it here in Europe? What is the dose and how to apply it in her situation? I don't have any idea and we don't have here any doctor that knows about this kind of stuff.
Any info /advice you could provide of any kind, I would be enormously grateful to you🙏
Doctor, what is the best brand of DMSO I can buy for a family member with liver cirrhosis? Where can I obtain it? I think DMSO is his only hope. Thanks so much.
I've used it with various natural products hoping for amazing results in hundreds of people and I must say it's a bit of a nothing burger. It seems to be excellent in acute C-fiber injury though. In muscle spasms, arthritis, nerve impingements and ligamentous/cartilage pain, acute or chronic pain, nothing's happened. Hundreds of individual cases.Only topical to be sure, but I can't risk internal applications and the articles suggest topical has a lot of utility. My attention is turning towards assessing effects on long-term outcomes for reinjury
I've been dealing with what was diagnosed as severe allergic contact dermatitis for maybe seven weeks now. The dermatologist thinks it’s a poison ivy type exposure. (I’m not entirely sure if the diagnosis is correct though top AI models agree with her.) I’m on my second course of oral prednisone.
(I’m trying an new approach to cleaning my skin today since I suspect I still have oil residue on/under my skin and when I weep fluid, I’m spreading the oil and rash.)
1) I’m concerned that using DMSO will potentially bring the urushiol oil deeper into the body. Amandha Vollmer warns against using it in this case in her book. Any thoughts on that?
2) Any concerns with using DMSO at the same time as oral prednisone?
3) Given I have a systemic inflammation going on, maybe applying DMSO to carry anti-inflammatory substances to body in an non-affected area?
4) Any suggestions you have in general with or without DMSO will be deeply appreciated. It’s been very difficult.
Could you please point us at a "how to" protocol page for both topical application and ingestion (eg drinking a dilute solution). For general ailments. I've lost track and need guidance.
One portion of this remarkably comprehensive piece was of particular interest to me: "Note: DMSO will leach many plastics at concentrations above 20%. For this reason, 15% or lower is often advised for situations where it has to come into direct contact with them. Conversely, when DMSO is mixed with water, it will temporarily heat up. This is a natural dissolution reaction between the two which has nothing to do with anything being leached." I have been wanting to nebulize DMSO for some time, but have held back due to concerns about contact with plastics. There are several plastics which are apparently safe to use, but no manufacturer of nebulizer supplies has responded to my inquiries about their products. I would likely be using only a few drops of DMSO in, say, 10-15 ml of saline. Based on the quote above, am I correct in assuming it would be safe no matter what the type of plastic cup? (I would dedicate one cup purely for this treatment, so there would be no concerns about contamination from other medications.)
My Golden Retriever has a Mast Cell Tumor at the base if her tail near her body. I have been applying a 70% solution 3X day externally to the tail and giving her the Tucker IV solution, (Hematoxylin /DMSO) orally, 5 ml, 6X throughout a day. Could I give her an injection of the Tucker solution at the tumor site? In addition 2mg of prednisone is given to keep the swelling down.
Elle is otherwise healthy and getting quality food and essential vitamins and iodine.
The Vets want to remove her tail, not a option for me.
Any guidance would be appreciated, I know you are super busy. Vern Boltz
My Golden Retriever has a mast cell tumor at the base of her tail. I have been applying 70% DMSO
externally #X a day, and been giving her the Tucker IV Hematoxylin dose orally, 5 ml orally for about 6X a day. Could I give her an injection of this solution at the tumor site. The Vets want to amputate her tail and the tumor is very close to her body. I know you are very busy, but if you have any ideas, it would be very much appreciated. I am giving all the proper High Quality Vitamins and Iodine as well. Thanks, Vern Boltz
Dr. Grindle found injecting it into human tumors didn't work, but there is otherwise very little data in this area. However injecting into the victinity might.
Rose Bengal seems to do better with direct injections, but I'm not aware of it being tried in that tumor type.
Both my husband and I (age 63) have a variety of ailments that the doctor says might benefit from DMSO. Intuitively, it seems the oral route would be most advantageous, but doc suggests topical first. Will we get the same benefit from the topical?
Yes, but I keep on updating and revising these articles as I learn more, and I don't want to be locked into information I no longer fully agree with (or feel is incomplete) which will happen if a book is written.
A lot of it are meetups and courses in Germany. However there are also a lot of groups on facebook (which you can find by searching DMSO and selecting groups)
I'm writing this short note to let you know how much I value you and your wonderful dedication to sharing all the information you have discovered over the years. I'm currently reading and saving
"The DMSO mixtures transform natural medicine", "How DMSO cures eye, ear, nose,throat and dental disease", and "Exploring how skin health goes hand in hand with whole body health."
I am a retired naturopathic and chiropractic doctor of many years and I'm learning so much from you.
Please let me know if you find a solution. I think these articles are wonderful but they cover so many issues it is hard to find what you need. I am on a PC
Does anyone know of a source of quality hematoxylin in USA that is pure enough to instill directly into bladder or rectum with DMSO to treat prostate cancer?
If you have not done so already, will you please compile this full series into a book? I am medically complex, poly-pharmacy and have so many uses for DMSO that I really need the information in one place. I am more than happy to pay for it in any form, including an indexed PDF.
Thank you,
Emily
hEDS, ankylosing spondylitis, Sjogrens, Raynaud’s, MCAS, dysautonomia, asthma, hypothyroidism, fatty liver, metabolic syndrome, PCOS, rosacea, high blood pressure, low kidney function, vestibular migraine with aura, macular degeneration, etc, etc. My list of specialists looks like the hospital directory. 22 Rx, ~25-30 supplements including vitamins, minerals, peptides, homeopathy, DMSO, herbs. I am forever running multi-variate, n=1 supervised experiments on myself. Had I known my BS in pre-med bio and chemistry was going to figure so heavily into my personal life, I’d have tried harder in organic chemistry. I’m a city planner by trade.
Is there any chance that you can share doctors info, who are using this in their practices. It is impossible to find them otherwise. And to share the “communities” where we can join others and learn more and give support. Until the US allows us to have this information, we have you, for which I am eternally grateful, but we need more. Thank you for your diligence and desire to help us without pharmaceutical drugs and surgery being the only remedy.
A lot aren't in english (and hence difficult to go through) but there are some currently active ones on facebook (you can find by searching groups for DMSO).
I wish I could provide some explanation but I don’t know. I have read to take it before a meal. So I am confused about the appropriate timing. If I come across any new information in the book I am reading, I’ll let you know.
All the reading I have done from MWD and others about DMSO, I have not found good information about oral ingestion causing any problems for someone with hip implants. If it is OK. I need some dosing advice. I have a lot of surgical scaring, but I'm most interested in one area in particular. On the scar there is a nodule of scar tissue. Can it be released by DMSO? I'm interested in oral for detoxification of metals and other environmental contaminants. MWD mentions taking with Chlorella or Cilantro.
You speak of the DMSO community, but I can’t find a community anywhere online. I was hoping for message boards or some-type of online forum for expert & newbie DMSO users to collaborate. For instance, I’m trying to recreate a DMSO-frankincense-hemp cream that is no longer available, but I’m having a hard time getting the texture correct. So I’d love to talk to people with more experiencing making DMSO creams about the issues I’m having. I also have somewhat random questions like can I use a silicone spatula to transfer my DMSO cream(s) from one jar to the next.
The issue is that most of it isn't in English or is on older forums people don't use as much now. There are also a lot of English groups on Facebook but they aren't as detailed.
Please add an index or some local search capability on your DMSO and really all of your articles. I am focused on Parkinson's and want to read every story you have on Parkinson's and DMSO. This search would apply to any condition and helpful to all.
I used to own a medical publishing company, and indexing was a major task in the production of scientific material. There are indexing programs that publishers use to list all “important” words, along with all page numbers that contain those words. It’s not perfect (indexes some common words; misses some unique words), but it’s better than trying to compile them by hand. (Not to mention automatically updating all the page references if pages shift with edits.)
In the meantime, Tom can print each article to a PDF, then use the Acrobat reader’s “Find in document” search function.
Wasn't thinking of a manual index, rather a search function for all articles with keywords. Google search with site: qualifier would work but might miss parts behind paywall. I will play with that for now. Don't want you spending time to write a manual index, you got more important things to do.
Thanks Doc; great review and details. . . not done yet but got to point# 10 and was confused; it sounds contradictory. . .
"With both topical and oral DMSO, people generally find that as time goes on, their tolerance to it improves. Conversely, if it’s used too frequently, a tolerance can develop, so it’s generally advised not to take it 1-2 days a week."
Please explain . . . "NOT to take it 1 -2 days a week", thx
I bought a bottle and two larger jars of the gel. I feel inflamed all over and I feel like my blood is sludgy. I have difficulty breathing basically I feel like my blood is not getting oxygenated. Can I use the gel like I would a moisturizer all over my body?
I'm interested in trying the galactose DMSO combination for my husband with Alzheimers which we are seeing both a Functional Medicine DO and a Naturopathic doctor for but neither is knowledgable about DMSO. My husband also has metastatic prostate cancer which he was being treated by a Urologist that gave him so much Lupron that it depleted his testosterone.I I I I I think that was the start of his AD. Can someone tell me where to purchase galactose and which brand is best.
This article was so full of information I decided to print it so I can study the parts I need. I'm doing IV chelation therapy and a bit confused how to use the DMSO with it. I was putting DMSO on my arm for something else when I went for chelation therapy and I kept blowing veins during treatment.I quit the DMSO in fear that it may of caused it. Hopefully rereading everything on it will help.
Wish I could find a medical practitioner knowledgeable in DMSO, especially for my husband.
I'm essentially trying to create that DMSO doctor network in the USA. Currently the people I know who started using it from these articles all told me:
•It performed miracles.
•Their practices filled.
•They've moved away from their old jobs/pratices they worked with to do DMSO full time.
•They can't currently be publicized here because they are already full of patients.
As time moves on, my hope is that their successes and patient experiences will make others want to become DMSO doctors to and have there be a greater supply of practitioners in the USA (whereas in Europe and Germany there are a lot more).
Galactose isn't hard to make so it should be easy enough to find a clean brand.
Thank you for your reply. Fighting both metastatic prostate cancer and Alzheimer’s is tough. He does UBI, organic diet, supplements and a lot of exercise and rubs DMSO on his neck and head. I keep thinking maybe we’re missing something And little support from family and friends because of most don’t want to admit our medical system has failed us. It’s genetics is what I’m told. You are a God send. Reading You gives me strength to keep fighting even when I feel alone.
We do all that in addition to organic fruits and vegetables, drinking reverse osmosis water and eliminating aluminum sources. We eat grass fed beef raised on a regenerative farm.
Doc, it would not be so hard to start a forum for people who are experimenting with DMSO. There, both patients and doctors could share, anonymously if wanted. Forums make discussion of subtopics much more user-friendly than substack. There are a number of plafforms that are pretty easy to set up, like for example https://www.simplemachines.org/ (the granddaddy of them all, I think).
Question about using for connective tissue disorder and lymphedema: is D-lactic acid the same as lactic acid? Where is the best source to purchase that plus mag lactate? Am I looking for a powder or a liquid solution? Thank you!
AMD I have had neuropathic pain caused by a surgery 25 ago. Several months ago I started using DMSO 70% gel over the scars as well as all areas affected by the pain. The reduction in pain has been remarkable. I am playing with the idea of also using DMSO orally to see if I can get further relief. I would not have tried DMSO if not for your work Thank you!
Question. Can DMSO reduce calcification in an Aortic valve? If so how would it be administered Thanks
It would be ever so helpful if you could list the DSMO information with the complaint/issue/problem at the top of the para then followed by the DSMO + whatever after that.
Readers could then go straight to the illness/problem that affects them rather than having to read everything to find a paragraph that is relevant to them. I have bought DSMO cream and liquid but I'm still not sure how to use or what to use for other than a direct application of cream for pain.
I did not do that because it would make the articles much much longer and harder to follow the key points to understand the subject in general (and more repetitive). I put the caveat about that in the article so they could just search for what they want to find. Conversely, if I say condition:do x y and z, people will do x y and z without the context to understand how to do it safely or correctly.
Having read all the articles with repetitive information makes it helpful to remember the haves and have nots. Also I would recommend buying The DMSO Handbook by the German author Fischer.
Eral - I kept thinking the same thing as I read through this amazing article. Or maybe put the complaint/issue/problem in bold font . . . Now I'm wondering if there is a way to do a search through a substack article. I'll have to go back in and check!
You mention using a solution in a spray bottle. But is there such a thing as a spray bottle that isn't plastic and can handle DMSO?
Natural Metabolites —You mention many have had success treating CFS while others have been used to rebuild connective tissues. Can you say which ones for each? Or do we get Fischer's book?
DMSOstore.com sells spray bottles. They’re expensive, but they’re made of heavy glass and have a high-quality sprayer that sprays an even mist, unlike the ones at the dollar store that sputter and spurt.
Combining DMSO with other substances usually strengthens their effect, as you describe.
My question is whether this applies generally only for the benefits of the other substance or also for its potential side effects?
Under the first hypothesis, the DMSO wpuld potentially allow to get similar results with a lesser quantity of the other substance, which would essentially be an economic advantage (depending on the cost of the other substance).
Under the second hypothesis, you could potentially have a major clinical benefit as you would be able to get the effect of a much greater quantity of the other substance without its potential side effects.
That's basically why DMSO works so well with chemo.
With pharmaceutical drugs you can run into issues with them potentiating an inherently toxic drug, in which case lower doses are needed.
I thought this would be an issue with natural substances, but most of the issues were either peroxide being too concentrated or the agent being too acidic.
I did not fully understand the second part where you wrote;
"I thought this would be an issue with natural substances, but most of the issues were either peroxide being too concentrated or the agent being too acidic".
Is it referring to drugs or narural substances? What does that mean and how can this be mitigated? I am asking this from my perspective as an (educated) layman.
Thank you very much. Sorry for asking about something that is excplicited in the article, I will go in-depth over all the precious information you so kindly share with the world!
Thankyou for this compendium of DMSO. It is a book in itself (I am printing off a copy for quick reference).
Do any DMSO combinations help to dissolve blood clots? I see DMSO helps with strokes and heart attacks but will it help to dissolve existing blood clots in deep vein thrombosis, brain capillaries, etc?
DMSO alone does and I know people who've done that, but a lot of other things with anitclotting activity have also been mixed with DMSO, some of which I detailed here. The main thing I am not sure is if it can work with nattokinase/lumbrokinase/serrapeptidase because they in theory are too large for DMSO to transport, but people have had success with heparin (which also should be too large to transport).
I listen to a lot of different shows on rumble. Wouldn't it be GREAT if MWD had a show!!! Meanwhile, the powers to be would surely take down rumble or prevent the show from airing. And maybe his/her info wouldn't be appropriate for just everyone to hear.
I totally understand! The info you put together and share I would say surmounts way beyond the sermon on the mount! Amazing Gems! Always ahead the game & right on target! And they provide incredible opening for many to roll forward in many wonderful exponential ways! Infinite Appreciation AMD!!!
Gadz no! I don't do podcasts, and vids only rarely, mostly for DIY kind of stuff. Takes forever to listen or watch compared to reading. Just bloody annoying... :-)
I have not heard of this being an issue. I found one study where patients were on antidepressants and DMSO increased the likelyhood of the treatment resistant depression being cured without any side effects. However, it used TCAs rather than SSRIs.
SSRIs? Certainly not close to each other. I'd space them far apart and start at a very, very low dose and gradually work up. SSRI toxicity is not a safe playground. There are some points in the above article to reference, regarding the conditions SSRIs treat. As a side not, I work really hard to get patients off those meds. It can be tough, but I promise its worth the effort.
Thank you for your reply Danbob. Yes, I agree, I'm thinking there shouldn't even be any SSRI's. A friend of mine has been on them for a long time, I forget which ones. Medicinal mushrooms seems to be helping some people get off of them. Spacing out dosage time makes sense. And milk thistle, dandelion, etc for helping with the toxicity.
85% of neurotransmitters come from gut microbiome. Need a good probiotic such as Gundry’s Bio3complete, B Complex, Magnesium and stop sugars, eat grass fed beef and butter, organic pasture raised eggs…
WOW! Amazing & Excellent!!!! Your work is Incredibly Exciting!
Question, what can you say about cervical myelomalatia?
Can it be resolved -cured? Could the spinal cord be restored? At the very least, I'm thinking dmso might be one of the best way to deal with the pain, topically and internally, and maybe with the addition of? Wild lettuce, or? A woman friend of mine has been seriously suffering from this condition.
I think it has a good chance to helping given the nature of the condition, but I am not aware of it having ever been tried. Since there are so many conditions DMSO could be tried on, most haven't been tested.
That said, I have read of things similar to cervical myelomalatia that did respond, and might have met the criteria for that diagnosis but never were diagnosed as such.
You're right! If anything, it could be the best possible ticket! Now I need to somehow convince my non believing friend to try it! I think both topically and internally.
Thank you! yes, I was just looking at that article the other day, scanning quickly. And MWD's article about the brain & spinal conditions. I didn't see anything addressing this condition in either articles.. I might've missed it. Maybe in the MANY comments, haven't had time to look at them. The core of this condition is the spill cord is softening, degenerating. I'm wondering if DMSO can restore the spinal cord. It makes sense that dmso with other agents could be very beneficial for addressing the pain. My friend can only stand/walk an hr or so a day (groceries' tc), otherwise she has to be on her back.
Please could you explain what "safely" means (in terms of dosage) in this sentence: "Rather, the only combination I am aware of is nebulized glutathione and DMSO, which (provided it’s done safely) is remarkably effective for asthma and otherwise incurable respiratory conditions"
Thank you, I just wondered about the safety of combining glutathione with DMSO, but Danbob has explained. I have been combining DMSO with 3% hydrogen peroxide in a 0.9% isotonic saline solution at the doses you recommended (ie. very low, 2 drops DMSO + 5 drops HP in 5 ml saline) but have found no benefit and some worsening. So it's the mechanics of the combination synergy effect of DMSO + something else that I do not understand. For example, if I nebulize DMSO in saline, do I have to follow immediately with the glutathione (or whatever it is) to get the DMSO turbocharged effect? Or could I still get the turbocharged effect if I do DMSO in the morning and e.g. glutathione in the evening? Or do I need to nebulize both simultaneously to get the DMSO turbocharged effect?
Rinse your nebulizer set with 99% dmso, then water. Then add 2.5mL nebulizer solution and add 1-3 drops of pure, pharma grade dmso. Can then nebulize Glutathione. Some don't bother and just do them together.
Well mostly, but I wonder if there is any drug interaction between DMSO and glutathione, even if one takes them separately. I was just a bit alerted by the phrase "provided it's done safely". How would it not be done safely?
That statement is about following the basic guidelines and being smart about DMSO's use rather than just jumping into without informing one's self. This is one of the purposes of all AMD's articles: to relay enough info so people can be safe, ie: not putting 99% in your eye, or not using it concurrently with heroin, etc. There's still alot we don't know but I believe the author has laid out some good general boundaries that can be used to guide DMSO's home use. Example: it is a vehicle for other substances and can increase their action. Meaning: If you spilled gas yourself, it would be wise to wash it off before using DMSO. Or, if you're on blood pressure (any med) medicine, you should wait until your medicine has absorbed before taking a dose of DMSO. Regarding DMSO and glutathione, there is a chance that high enough doses of each could interact and render them both inneffective. For this reason, I'd use dmso, wait a few minutes, then use the glutathione.
Hi Patricia! I don't worry about this issue topically. I just apply and go. Leave on for at least 15-20 mins. If taking orally, its best to wait 2-4 hours after you take your meds. Generally, very safe. For the knees, I'm fond of applying DMSO, then about a nickel sized amount of Diclofenac gel spread on top. I had a miraculous response in a guy who was post total knee replacement. Ortho left one leg 1/2 in shorter than the other. On all the pain meds. Ortho got an xray and "everything was fine." Not even kidding, he called my nurse the very next morning to report he was conpletely pain free. No more pain meds and a real success in my book.
Some claim you can make CDS with Safrax tablets (https://safrax.com/shop/). I was wondering your thoughts on this as it would be much easier than Andreas Kalcker's method. Thanks!
I really don't know. There are solid activators (some of which are toxic) but I do not know what that one contains, and it's not listed anywhere. Excluding that, it does allow you to control the dose which is great.
I had reached out to the company a couple years ago and have copied their reply below. If you have time, please reply to let me know if you think it would be safe & if it would result in the same outcome as Andreas Kalcker's method. Thanks!
Thank you for your interest in our chlorine dioxide tablets!The ingredients of our tablets are:
- Sodium Chlorite,
- Magnesium Sulfate,
- Sodium Bisulfate (acid activator).
When the tablets are mixed with water, it becomes pure Chlorine Dioxide (purity is 97 to 99% depending on laboratory used), the rest is just common salt.
Our tablets are compatible with organic culture and fruits and vegetables processing. Our acid activator is Sodium Bisulfate and not acid, so we do not have residuals of chlorate and perchlorate (long term thyroid side effect), which is monitored and regulated in Europe. I hope I was able to answer your question, please do not hesitate if you have any further questions.
1) I wanted to go with the lower doses to avoid any risk. The other issue is that at higher concentrations it can leach plastic. That said, sometimes there are excellent results like yours.
2) With gums, part of the reason lower concentrations are advised is to avoid issues for people with fillings with materials that can be leached.
3) Never heard of that use for DMSO, I will need to tell some of my colleagues about that. I will look up Syrian Rue for benzos, I have not heard of that either.
4) Generally it sounds like you tolerate higher doses than most people. There is a lot of variability in the dosing, so I was trying to present what would be the best fit for the most number of people.
I took a larger dose of syrian rue once (8 caps), and spent a lot of time throwing up afterwards, maybe an hour later. It was remarkable that it was completely not-unpleasant, normally throwing up is gaggy and hard on the body. This was easy! I was hiking, puked, continued to hike, puked again, no problem. No gagging or heaving. :-)
That was a focus of this article. Has to be in combination with other antilyme agents unless you are just trying to heal symptoms of lyme rather than to eliminate the infection.
Yes. TB for example is typically treated with several antibiotics, however DMSO's properties allow it to be treated with fewer due to the potentiation. The same is probably true with tick borne illness and biofilms. Just as we've seen in cancer, DMSO can transport the meds through biologic barriers that prohibit standalone therapies. Although I haven't seen it, I'm fairly certain someone has done it and written about it. My idea would be DMSO+clove oil+ doxy or piperacillin or garlic oil.
This is, in my opinion, the most valuable article on DMSO I've seen yet. The therapeutic possibilities here are truly incredible—limited only by our imagination. Importantly, this isn’t just information for healthcare professionals; it’s accessible to everyone. If people approach this with courage and follow the guidance, we really do have a chance to reclaim our health from the traditional medical system. In my own practice, I now use DMSO or a DMSO combination in about 80% of cases, and the results have been remarkable. The potential for self-healing outlined in this article is inspiring. Save it, print it and keep a copy nearby.
A few of the anecdotes in this article came from Danbob
Working with editors is very challenging because they will often change your intended meaning and it can be difficult to catch the change that was made if it's subtle in a large body of text. In the case of Harmut Fischer's work, all of it, except his 2015 book, is in German and hence not very accessible. However his 2015 book is in English and hence is one of the best references on the market. I apologize for the intended meaning getting changed in the final version.
A Midwestern Doctor,
I'm wondering about your response to the following link on Substack that runs contrary to your articles on DMSO.
https://open.substack.com/pub/medicinegirl/p/disastorous-dmso?r=1qgo8a&utm_campaign=post&utm_medium=web&showWelcomeOnShare=false
She keeps posting that to get traffic. It's highly inaccurate, but each time we try to explain (along with dozens of readers who have tried as well) the specific points, she says we are brainwashed by the medical field and don't understand what we are talking about (along with telling everyone who says DMSO helped them a lot and had no side effect that their experience, for one reason or another, doesn't count).
Her brand essentially is saying commonly used natural therapies are actually toxic and you need to just do detoxs and elimination diets, so if you go through her Substack, you will find some pretty ridiculous stuff used to smear other therapies. When I looked at her arguments, I realized that she was juxtaposing common issues with other pharmaceuticals onto DMSO (which is a common thing people do, as due to it being hard to fully understand a subject, they always juxtapose their pre-existing knowledge base onto it).
Regarding the deaths, the points she's omitting is that in all but one of them, another product was involved, as on FAERS if someone has a lethal reaction to a drug, they list all the other things they were taking as well, and in those cases, it was more likely culprit of death, and in many cases, they were being given intravenously (where a higher risk of death, particularly the onyx cases where the DMSO polymer mixture was being used to patch an otherwise fatal internal bleed and hence was a high risk situation). When I wrote the safety article, amongst other things I read through all the FAERS reports and explained them, no one else has done that. Conversely, most medications have thousands of deaths in FAERS, many of which can be directly attributed to the drug. The fact that over roughly 40 years 21 deaths are in there almost none of which can be attributed to DMSO is an insane safety profile. The primary drug DMSO replaces (NSAIDS like ibuprofen) are well recognized to kill hundreds of people each day, and their toxicity is rarely discussed.
In short read these two article, critically compare them to hers and then make your own decision:
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety
https://www.midwesterndoctor.com/p/the-fdas-war-against-dmso-and-america
Thank you for taking the time to clear this up!!!
Decided a while ago to try a teaspoon internally. After a few days, amazingly, I noticed I wasn't coughing! I'd had a regular chronic cough almost all year! And the cough is gone! Thanks so much, Doc! I had been told I had beginnings of heart failure, and a cough sort of goes along with that. I'm feeling much more confident! Workout three days a week going a mile on treadmill, and i'm 82. 😊
Wow. That's great. Did you take a teaspoon with water, or something else? Have you used a nebulizer?
Long ago I tried it in a little nebulizer, and the plastic fell apart…so teaspoon in water is what we are using. Nice to not be coughing!
For anyone interested, here's some information on making a 12% magnesium chloride solution to be mixed with DMSO for musculoskeletal and other issues.
I could only find two liquid magnesium chloride solutions online, one from Nutricology and one from GNC. I contacted both companies asking for the percentage of magnesium chloride in their product, and neither replied.
So I decided to buy magnesium chloride flakes. I ended up buying a 50-pound bag of magnesium chloride from an industrial supplier (MgCl is used for deicing roads), but you can buy small quantities from companies such as Greenway Biotech (e.g. see their Organic Magnesium Chloride USP).
As for making the solution, "12%" refers to weight, not volume. So you'll need a gram scale to weigh the magnesium chloride, preferably one that measures to the hundredth of an ounce. I decided to make the solution using 24 fluid ounces of water. You can find a converter on the Internet to easily get the weight in grams for any volume of water.
Knowing the water weight in grams, you can obtain the weight needed for magnesium chloride by applying the following formula: (Weight of water in grams)=.88X. Here "X" will give you the total weight of the water+magnesium chloride combination. Then subtract the water weight from "X"--this will give you the weight of magnesium chloride in grams needed for the solution.
Then you just weigh out the magnesium chloride flakes on the gram scale (I measured to the hundredth of an ounce, but of course you don't have to be perfect). Then dump the MgCL flakes into the water and mix with a spoon until the flakes fully dissolve--this only takes a couple of minutes.
And that's it--you've got a 12% magnesium chloride solution.
Thank you! Given how long this article is, I can't go into that level detail for a lot of these topics.
You're welcome--I hear you, your articles are extremely detailed, but you can't possibly research everything!
https://www.greenwaybiotech.com/products/magnesium-chloride-usp
Great note. Any ideas on where to get D-lactic acid?
Thanks, Metacrawler is a good search engine for hard-to-find items. I see that Neogen.com and Chemimpex.com sell D-lactic acid.
Thank you! I was really hoping to find something already pre-mixed 21% :) for eczema water.
(Edited: Please disregard my previous post, as I mentioned a product that I mistakenly thought was a liquid (it's actually a solid).)
It looks like you can't buy a commercial preparation of D-lactic acid at 21%. I found two liquid formulations of this product online: Neogen's Megazyme D-Lactic Acid Standard Solution and R-Biopharm's Enzytec Liquid D-Lactic Acid.
The spec sheets for these products don't specify the percentage of D-lactic acid, so you'd have to contact these companies to obtain this information. If they provide you with the percentage of D-lactic acid in their product, then you can make your own 21% D-lactic acid using water as a dilutant.
You can use the following formula: (C1) (V1)=(C2) (V2).
Here C1 is the concentration of the starting solution, V1 is the volume of the starting solution, C2 is the desired final concentration, and V2 is the desired final volume.
So let's say you're using a 99% D-lactic acid solution and you want to make 20 fluid ounces of 21% D-lactic acid. You'd use the following values in the above formula: C1=99, C2=21, V2=20.
Then you'd solve for V1--the answer here is: 4.24 ounces. So you would use about 4.25 ounces of a 99% D-lactic acid solution and 15.75 ounces of water to yield 20 fluid ounces of 21% D-lactic acid.
If Neogen or R-Biopharm fail to provide you with the percentage of D-lactic acid in their product, then you would have to make your 21% solution using a weight instead of a volume calculation, which is a bit more complicated.
Thank you for your impressive and detailed response
Roger, is this for topical or oral use? Thank you! Mare
On Friday, I disturbed an old disintegrating stump by kicking it. A piece fell off and a swarm of wasps came out charging me. I had on socks and Jeans, Many got me on my ankle through the stocking.
I got into the house and immediately put DMSO on a cotton ball and held it on my ankle. Also put some DMSO on my whole foot. It never swelled up, pain resided, Still tingled some for a few hours. Slept well overnite without pain, and next morning, could not feel anything. Thankful I had the DMSO available.
Dorothy
DMSO is great for bites!
Thank you AMD, for this huge effort. I am currently planning to use many of the snippets of information found herein to prove out some additional uses for DMSO. One of those will involve the use of Red Elderberry, I found recently in abundance on my mountain. My wife told me not to eat them, because their seeds contain cyanide (edited 23 AUG 2025 TO REMOVE ERRONEOUS MENTION OF ARSENIC)... actually similar to the apricot seed and apple seed. When I considered this fact, I realized that B17 has been used, (Laetrile) to treat cancer, and was buried by the system. These Red Elderberries are quite delicious, and would be a very pleasant way to treat cancer, combined with DMSO. Another project I've started to work on is the use of catechins from the Red Alder... a little bit bitter to taste, and woody, but edible. Because the alder is a very unique tree, when the bark is removed it turns color, a deep red... another natural dye, and as you noted, several natural dyes are in fact used to treat cancers. So, thanks again for all the knowledge you've shared... we will set forth and put that valuable effort you have expended to good use. God Bless you.
Thank you! Let me know how it goes. That said, in the case of Laetrile, the reason it "worked" was that while it was "toxic" it (allegedly) only released cyanide in tumors, so it had a selective toxicity for cancers. That's different from taking something which is just toxic in general.
Thanks a lot Doc. I will stay in touch. BTW, cabbage family group, cruciferous veggies, also contain "toxic" compound isothiocyanate... so deadly, I am told, that it cannot be transported on public lines... yet it is active in stopping the growth of tumors... and I eat some pretty much daily... another great candidate for compounding with DMSO. I have been growing cabbages for personal use... (I'm not kidding here... two years ago, my cabbages reached an amazing 53" in circumference, and a weight of 28 pounds!) I have lots of sauerkraut for healthy food. I am grateful for all you do Doc. Thank you again.
Share recipe for sauerkraut please?
Sure Laura, no problem. Ingredients: Fresh cabbage, clean, shredded, and salt TO TASTE, (not necessary to have a lot, because fermentation is the preservation process, not salting.
THE PROCESS: In a large bowl, (we use stainless steel), add layers of cabbage about 1-1/2" deep, with some salt, and then bruise the mixture with a wooden club, like the end of a baseball bat, to force juice to show abundantly. When you have sufficient cabbage bruised, add it to a one quart mason jar... (any size will work fine), and PACK THE BRUISED CABBAGE INTO THE JAR TIGHTLY, using an appropriately sized wooden 'bat'. The idea is to fill the jar to about 1'' from the rim, making certain that the cabbage is tightly packed, AND, that there is juice covering the cabbage. I leave a 1/2" space between the lid and the top of the juice. Note that you may add other things, like shredded carrots, peppers and such during the mixing process. After wiping the rim of the jar, put on the Mason jar lid, and tighten the lid about finger tight, wipe the outside of the jar clean, and place it into a tray, a cookie sheet is fine, to catch the expelled juice during the fermentation. Ferment on the kitchen counter, or any shelf, at room temperature, warmer is O.K., but cooler will slow or stop the fermentation, which generally, and usually takes about a week after stuffing the jars with cabbage. This method is very reliable, hassle free, and the resulting sauerkraut lasts a long time, without refrigeration. After opening the jar for use, however, refrigeration is recommended. DELICIOUS... It is noteworthy that sauerkraut made in different homes tastes differently, likely due to different biomes in each home. A note about the process... the concept is to ferment in the absence of air... so tight packing is important, juice over the cabbage in the jar, and the right amount of pressure when putting the lid on. The gas from fermenting will force it's way out of the jar by forcing the lid to give a bit, while preventing air from entering the jar... it works very well. When the fermenting is done, gas stops forming. Wipe the jars again, label them with the date, and then store them in a preferably cool place till they are needed. The longer the sauerkraut stays in the jar, the richer the flavor. We've used sauerkraut done this way for many years, and can use the finished product in from about one week up to several years. We've not had even one failure. WE DO NOT PROCESS AFTER FERMENTING, BECAUSE THAT KILLS THE PROBIOTICS IN THE SAUERKRAUT. I hope this was helpful Laura. All the best.
Doc, just to let you know one of your readers noticed I used the word 'arsenic' erroneously, instead of the intended word 'cyanide'. I did apologize for my error, I hope not to make another mistake. (Editing done 23AUG225 replace the word 'arsenic' with the word 'cyanide'). Sorry for the mix-up, and thanks again for all your work you've been generous to share with us.
Hi, hope you are recovering from your concussion! Yikes, a lot of unfortunate accidents can sure occur on the farm, especially with tractors!!
Cheers and be well!
Thanks Isabela, all the best, and God bless you. By the way, thanks for the advice on how to safely use the Elderberry. Mine are wild, Red Elderberry, up on my mountain, and they showed briefly, for the second time, and got my attention this year... I have found them in four locations, and now plan to propagate them. In noticed that the birds and the black bears eat them very quickly, and realized they must have medicinal value. I have a sense that the CYANIDE in the seeds may actually be useful for cancer treatment, and note (jokingly) that I haven't seen any birds or black bears with cancer... thanks for being a good sport Isabela. (yes, not arsenic... oops).
Hello, a correction needs to be made here....elderberries Do Not contain arsenic. My husband and I grow 5 acres of black elderberries. The elderberries contain Cyanogenic glycosides (CNGs)....let me quote from the journal Molecules: "CNGs are naturally occurring plant molecules which consist of an aglycone and a sugar moiety. Hydrogen cyanide (HCN) is released from these compounds following enzymatic hydrolysis causing potential toxicity issues." However, once the berries are harvested and de-stemmed and cooked at 160 degrees for about 20 minutes the HCN is neutralized. We harvest the berries, de-stem them (with a machine) and juice them and freeze the juice which is cooked later. It is not advised to eat the raw berries. The seeds should be strained out of the juice before or after they are cooked. Probably not good to ingest all that seed material, might be problematic for people with gut issues like diverticulitis.
Sorry Isabela, I did mean to say cyanide, not arsenic. My brain is not working right since I gave myself a concussion in May 2025. You are entirely correct, please accept my apologies, to you and all the folks I've inadvertently misinformed. Perhaps I should get more sleep. Thank you for your sharp eye, kind correction, and watching out for the truth. Much appreciated. (I apologized to my wife also... she did say cyanide, not arsenic... she also insisted on that CT SCAN the day after the concussion... she said she knew something was "not right" when I told her I had knocked myself out in the garden on the bucket of the excavator... the day before, and forgot to tell her about it.) Thanks for covering my 'six'.
Isabela, We have some elderberries on our property . . .
any suggestions for the better variants of elderberries for making the juice? and,
source on the de-stemming machine you use?
Hi, we grow Bob Gordon, Marge, Pocahontas and Ranch. We originally got our plants from Indiana Berry co. We propagate them ourselves now. They are very easy to propagate in the Spring. We take cuttings from the dormant stems and put them in moist soil in pots. They root easily. Our de-stemmer came from
Buehler's near Springfield Missouri: buehlerfarms.com
The de-stemmer wasn't inexpensive, but if you search around you may be able to find one cheaper. If you freeze the berries first in bags it can be easier to remove them from the stems. If you are only doing small amounts of berries you probably don't really need a de-stemmer. Elderberries are totally worth having on your property. The flowers are great for the pollinators and are also usable
for tea and other things. Of course you wouldn't want to harvest all of the flowers because then you'd have no berries. All around a great plant!
In central Europe we fry the elderberry flowers in batter. Delish!
Thanks Isabela for all the detail.
I really appreciate it!
Has anyone inquired about injecting DMSO?
Hi Deb, yes, there has been mention of injecting DMSO under controlled conditions. (I have to be careful, I am still apparently under the effects of a concussion). It was Dr. Stanley Jacob, I believe who mentioned it. Here is a snippet from Google:
What is the use of DMSO injection?
DMSO is used either alone or in combination with a drug called idoxuridine to treat pain associated with shingles (herpes zoster infection). Intravenously, DMSO is used to lower abnormally high blood pressure in the brain.
I am unable to recall all of the applications that were mentioned, but if you Google Dr. Stanley Jacob, there is a wealth of information available. All the best, David.
Thank you David
Another testimonial - my 8lb cat recently sprained her hind paw and a had a minor abrasion on it as diagnosed by xray. I applied 50%dmso directly to the paw twice a day for 3 days while also giving her two drops of comfrey leaf tincture in her food twice a day for 5 days. She showed immediate improvement in one day and her limp was completely gone by day 2.
Just finished watching that old "60 Minutes" episode. Wow. The FDA has been protecting Pharma for a long, long time. #LatherRinseRepeat
Thank you, thank you, thank you, for your impeccable work.
DMSO is an enemy of The big Pharma protocols for drugs and injections. DMSO in plastic bottles will probably leach out Bis Phenyl A , an estrogen interrupter that is resident in plastic bottles wall surface. through the molding process of the bottle. It is interesting to note that DMSO is excreted through the kidneys and is not impacting hepatic function. Most of the prescription drugs that are consumed today. do just the opposite.
I have found using a topical form of a pain reliever in the form of a gel and mixing it in equal amounts with pure DMSO allows me to sleep all night .
It is a blessing. The only question that I have is that the half life of DMSO is 2 to 3 days.. therefore is there a risk of overdosing on DMSO and what are the consequences?
In the pharacokinetic studied they have not found regular DMSO use causes it to reach excessive levels in the body. Conversely it's also unlikely anyone will ever get near a toxic dose because it's LD50 is so high (e.g., the prisoner study covered their entire body with DMSO multiple times a day for 90 days and there were no issues).
Keep in glass container and do not put in fridge.. it will crystalize.
Other MWD articles suggest not taking it on the weekends, then take over the week.
Hey Thomas, can you provide more details . . . which pain reliever in form of a gel?
So, you sleep ALL through without waking? Fantastic.
I go to sleep easy, but have hard time staying that way.
I buy Voltaren gel from Costco under their generic brand! Then I buy 99% DMSO @Amazon and mix them together in equal quantities. I think it’s working for me rather than taking Voltaren by mouth and having it spread through the whole body.
What about the inactive ingredients in the gel? I see Fragrance, Polyoxyl 20 Cetostearyl Ether, Propylene, and Strong Ammonia Solution listed, among others. No negative reaction from these being transported into the body along with the diclofenac?
No rash etc. I guess they are there to allow absorption through the skin.
DMSO is metabolized to DMSO2 which appears in the urine. AFAIK there isn't an indicator for that yet (like with pH indicator) but that would be feasible, with color shades for concentration. When IR spectroscopy is available that also would work well to get to know the range for safe level as the absorption spectrum of dimethylsulfone is specific.
Does that mean DMSO attaches to a Oxygen molecule.
To an oxygen atom is the net effect but as a rule biochemical processes are more complicated than that.
Oh, thanks for the reminder. I previously took it orally and found it kept me awake. I've been putting it on my scalp at night now and that's probably why I'm not sleeping well.
Sue, do you put the DMSO alone on your scalp or combined with something else? Once a week, I mix DMSO with a hair oil that is supposed to promote growth, but I've not been doing it very long. Do you notice any hair changes with the scalp application, such as greater growth or change in hair color? Thank you.
interesting. Your experience sounds opposite to that related by Thomas, above.
Me too.
Almost 4 weeks ago, I went to get on my daughter's treadmill. She usually helped me. Well, I hit the wrong button and it went so fast that I wound up on the floor. I did not break any bones, but my ankles and top of my thigh got scraped up pretty bad. It has been rather painful and I should have asked my daughter to use DMSO. I am healing, but I think that I would have healed faster, if she had used it and would not have been in so much pain. She used all kinds of other things like colloidal silver, fresh aloe vera from a plant, etc. I had no desire to go to ER and be treated. A neighbor across the street went there for a leg problem. Something went wrong and. he had to have his leg amputated.
Very impressive!!!! and overwhelming. However, I bet classically trained western physicians would be more overwhelmed than I am!
I wish to add one factor, a biophysics phenomenon best illustrated by a UV light shined on the body. I apologize up front that this is longer than I would have wanted because it brings many concepts together: A UV light projects quanta of high energy that are absorbed by the body and create an increasing concentration of OH• (hydroxyl radical) in the body. This is quite similar to the biochemistry described as "metabolic syndrome". For the past 20 years, I have studied this energy as a form of energetic pollution that is carried by the air and is in equilibrium with the human body. Car engines produce massive amounts of this, which is one of the reasons why people in cities tend to have high levels of chronic metabolic disorders than those far away from major roadways. I have developed a variety of devices that can absorb this "free radical" energy from air, magnetic fields, and copper wires. (EMF sensitivities). I also have devices that draw it from the human body. The result is a gradual reduction of oxidative end products like cataracts.
OK. On to DMSO. Based on your articles I purchased a jar of 100% DMSO gel. I was amazed at the burning sensation of my skin. (a new phenomenon to study!!!) I discovered that younger people have less of that burning than us older people, suggesting that this phenomenon accumulates with aging. Was this related to that energetic pollution I had been studying?
I applied DMSO to a small patch of stiff muscle and waited for the burn to show up. When it did, I applied one of my electromagnetic devices (that vacuums out this ionizing energy) to the center of the patch. The sensation immediately shifted to a more comfortable tingling, and to my amazement, lasted 1/2 hour or more. To me, this meant that the DMSO was dissolving old deposits of free radical end products like AGEs and releasing the quanta of high energy stored in the bonds of the free radical end products. It seemed this energetic pollution was flowing to my device from an expanding area of the body as the DMSO penetrated through the body dissolving free radical end products in it's path. This suggested to me the possibility that such a combination of DMSO and extraction of quanta of oxidizing energy might be a form of rejuvenation.
Then someone introduced me to the little H2 infused water generator bottles available for $30 on Amazon. As I studied them, they work by having H2 gas combine with OH• (hydroxyl radical) which forms water molecules within a rich mix of aqueous electrolytes, converting that oxidizing energy to heat energy dissipating harmlessly into the body. I found that, if I drank a few ounces of the H2 infused water, waited 1/2 to 1 hour, then applied the 100% DMSO, I got absolutely no burning. A Grok study showed me that, by greatly reducing the hydroxyl with the H2 water, I was initiating a cascade of reduced free radical levels of lower oxidizing potentials in my body as well.
Based on this I propose that DMSO combined with antioxidants might work better in reducing inflammation because DMSO alone releases the high energy potentials from dissolved free radical end products back into the body contributing to the pool of oxidative agents like hydroxyl which then just re-form new free radical end products in other parts of the body.
For those who don't get skin burning from DMSO, this might seem unimportant, but for us old people with a lifetime of accumulation of free radical end products like AGEs, this combination of DMSO with H2 water or perhaps another form of hydroxyl level antioxidant might provide a major reversal of one of the forms of aging.
That is really interesting. Thank you for sharing.
Thanks for this. I noticed that after bathing in a chlorine dioxide solution several times, I get far, far less burning than I used to when I apply 100% dmso to my skin.
Thanks for sharing your observation and hypothesis. Two questions:
1. Where would hydroxy radical be deposited in the body?
2. Would you mind sharing some of the devices that you use? Like hydrogen water generator and some that you have invented (or similar ones).
Thank you!
Hydroxyl radical reacts with almost anything, so I would think its end products can be anywhere you look. 2a. For Hydrogen Water Bottle, type Hydrogen water bottle into amazon. for my devices go to chi.us
I rolled full strength DMSO on my face. It really burned but in 5 minutes the pain was gone and so was the terrible sinus congestion I was trying to treat. It did leave my skin irritated but I would do it again.
That's why I tell people to use the lower doses, but in a lot of cases it works out like you described!
I used the 70% gel on small areas of my face (I read your warning and stupidly ignored it). I was freaked out slightly when my face started swelling but I just added more aloe and it calmed down and the next day was fine. But the amazing thing was that I had noticeable mental clarity (I have constant brain fog and chronic fatigue) so that was a happy accident! I also applied it to a pimple that was completely gone the next day.
Props to you for persevering. 70% gel on my face is about all I can stabd for the first 10 minutes. But to clear terrible sinus congestion, it would be worth it.
Is your sinus congestion from a cold or allergeries? Mine is just because I'm congested. I've tried everything from xylitol sprays to steroid sprays to flushing with NS to oral sudafed (the strong one) to antihistamines. I hesitated to use the DMSO because what I read was for sinus issues. PS I was diagnosed with a deviated septum and had a septoplasty over 3 months ago, well, I'm still congested!
Wow! This article is so timely for me! I'm at the end of a "course" of Lion's Mane which I use in 3-4 month stints for Parkinson's - after which time it stops being effective. At this point I was not sure what "experiment" I was going to try next - but with this information I'm inspired to try mixing DMSO and Lion's Mane. DMSO alone has been effective for pain, muscle fatigue. We will just have to see what this combo turns up. Thank you for your amazing contribution to humanity!
https://www.medicalnewstoday.com/articles/magnesium-threonate#benefits
https://journeywithparkinsons.com/2020/03/05/importance-of-magnesium-in-the-brain-and-magnesium-threonate-is-neuroprotective-in-a-mouse-model-of-parkinsons/
I could see that helping. Would love to know your experience (although it's also possible the DMOS alone with).
@makismd on X has posts about ivermectin/fendbendazole curing Parkinson’s . Just type it in the search bar when you click on @makisMd
Awesome! Keep us posted. :-)
SIBO yogurt is what Dr Davis (Super Gut) promotes. It's great stuff!
Thank you for all the time spent on this article, it is Invaluable!!! The possibilities are endless. I have printed it off and now can spend the time reading!
In appreciation
Thank you. Crazy part is that this is just the start.
Well I hope so! My partner is a Naturopath and our mind is blown! Keep up the good work, we appreciate you.
I've commented before on success with DMSO, but three days ago I had to put it to a much bigger test. A teeny fragment of bone is resting on the nerve near my C-4 vertebra. This situation came on fairly suddenly, and one false move takes me from discomfort to white knuckle pain that has me sobbing and gasping for breath.
After a day of this hell (which standard pharma pain meds barely touched), I suddenly remembered my DMSO. I used 10 ml of an 80/20 solution, used a dropper, applied to my skin and rubbed it in.
After about 15-20 minutes, I started to feel it work. Soon most of the pain was gone. GONE. I could walk upright, move my left arm. Anyone who has had nerve pain knows how difficult it is to get any relief at all, yet DMSO has made it possible for me to function with almost no pain as I wait for my next doc appointment (to take care of the problem for good).
The information you provide here is a public service, and you are making a huge difference in people's lives, MWD. Thank you from the bottom of my heart.
Wow, wow, wow. I have to quit 1/2 way through. What a remarkable post. I have
to sleep.
I recently started Turmeric plus curcumin in fat for pain. I decided at some point today to add DMSO. Your article gave me further resolve.
Hello Dr Linda. . . could you elaborate more? what kind of pain? planned ratios of DMSO and Turmeric?
. . . in fat?! huh?
. . . I thought Turmeric had ciurcumin IN it?
Apologies for being so tardy. Here is the article link
https://articles.mercola.com/sites/articles/archive/2025/05/30/curcumin-benefits-inflammation-brain-gut.aspx
Wonderful article. Many thanks.
I'll be passing along some of the information to a friend who suffers from Lyme disease.
I have instinctively been using DMSO alongside tallow, castor oil & CBD in pure forms. I’m happy to know these instincts were correct.
A DMSO/ luteolin mix could potentially work for grey hair.
Topical and oral administration of luteolin showed an anti-graying effect on hair without exhibiting any visible signs of toxicity in mice.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11673595/
Hm. How about disolving PABA in water and mixing with DMSO? PABA was trialed in the 40s for grey hair with success.
It’s easy to experiment. PABA alone, luteolin alone or both together with DMSO. The worst that can happen is the hair stays grey.
Copper helps
New subscriber here. This is excellent information and very much appreciated!
I have a forward curve in my neck and upper back that prevents me from raising my head, or turning it side to side. It is fairly painful. Today I applied a product from BearCat Body Care Essentials LLC
https://barecatbody.com/?se_activity_id=145831395520&syclid=d2fomunigtds73av1hi0&utm_campaign=emailmarketing_145831395520&utm_medium=email&utm_source=shopify_email
It consists of 50% DMSO, and 50% black Jamaican castor oil. I transferred it to a rollerball bottle for easier application. After applying it to my upper back and shoulders, it became warm, and within minutes the pain was gone, and I could raise my head without pain, as I have been unable to accomplish for four years
New Subscriber here. Thank you for your work and dedication to this topic, and the health of others. This is the most complete source I've found for using DMSO, and I am new to it. The dosing information and natural combinations you have here are an invaluable source. I look forward to being more self-sufficient int his area, and moving away from the medical 'treadmill'. Thank you again for your work.
Wow! I need to study this. My 98 year old father has such trouble sleeping and also has some dementia. We are going around in circles with the main stream health professionals. Meanwhile he suffers. I would love some help in using DMSO for him.
Debbie, I have had long time issues STAYING asleep and my latest and fairly workable solution includes spraying a Magnesium solution on bottom of my foot, rubbing it from that foot onto bottom of the other. I sleep pretty well with that. I used to take Benadryl tablets but found out there are some definite side effects that could be generated long term so stopped it. https://www.sevenminerals.com/products/sleep-well-magnesium-oil-spray-natural
I do the same with Magnesium oil, though I use a pretty small amount (just a spritz and then rub it in) on the back of the neck. Works especially well when I wake in the middle of the night and have trouble going back to sleep. Allows me to wake at a normal hour without any lingering grogginess, unlike Benadryl or melatonin.
So, figuring you tried this with your Dad, to no avail?
I take cannabis infused coconut oil right before bed. It kicks in after I go to sleep and wears off before I wake up and helps me sleep through the night (but not fall asleep since it takes awhile to kick in)
I make some CBD tincture with MCT oil. I use Bubba Kush CBD flower. It works as well for me as the cannabis. So if you can’t get cannabis flower, this seems to work for sleep too. I also ground at daybreak which helps with circadian rhythm. To me, this has helped tremendously.
any link for that stuff?!
I make it as it is legal in my state (one ounce of bud to 2 cups coconut oil). I only need 1/4 teaspoon to sleep through the night but my husband takes significantly more. I use this recipe but started skipping the step of freezing it because it was too much trouble and I use sunflower lecithin instead of soy: https://dudegrows.com/make-potent-cannabis-oil-aka-canna-butter/. I take the leftover buds after squeezing out as much oil as possible and make tea.https://wakeandbake.co/weed-tea/. It's hard to control dosage with the tea. I drink slightly less than half a cup and then meditate once it kicks in. I routinely hallucinate on the tea as it is super strong for me(I don't use it every night as I don't want to get up the next day!) I don't know that others would though as I have drank ayahuasca previously and I think it primed my brain for hallucination.
If you're waking up between 3 and 4 pm, try taking milk thistle before bedtime. Your liver detoxes between 1 and 3, so toxins reach a peak of being dumped out a bit later, and whatever it's disposing of is waking you up. It's like when you do a parasite cleanse you might need to take Ornithine before sleep because of all the ammonia that forms when certain parasites die. Also consider not eating any carbs for dinner or later, because your blood sugar might be spiking, which will also wake you up.
I think the light researchers that suggest that late evening-before bedtime light should be 2500K or less (amber like a fire , candle,or low wattage filament bulb) are likely correct that our wonderful 5000K work lights and bluish screens are really messing up our melatonin sleep chemistry. Fortunately and unfortunately our holistic environment has massive influence on health and restful sleep. Lack of restful sleep is destructive for cognitive functioning.
I can see the need for an Encyclopedia of DMSO remedies. So I carefully looked, there should be a DMSO mixture for arthritic joints, what other components would be in the mix? I tried castor oil and dmso, didn't seem to do much, also tried ivermectin, the ivermectin stayed a white color on the skin, never did absorb, dmso went on first. Arthritis is an infection so I would guess substances to clear infections??? Regarding prostate inflammation and enlargement, how on earth could dmso be used, other than a topical mix as in a suppository?
I am trying to put that together. That specific issue essentially is DMSO, and if not DMSO one of the combinations I listed for it here.
Yes. Please write a book. A table of content would be helpful, and as well listing of mixtures and purchase locations (at least for reputable DMSO). I'd buy it for sure!
I will buy it. The article was great, but I am overwhelmed . I also read Fischer’s book today.
Duane Hayes: What i learned back in 1986 about arthritis...remove the cause! i was in intense pain and couldn't lift my arms...I examined my diet to see what could have caused it. I saw that I had been eating bread, since a neighbor who worked in a deli started bringing me some regularly. So, I stopped the bread and within two weeks, I was pain-free and totally flexible. A few months later, I decided to find out, if removing the bread was the answer, so I started using it again. Within a couple weeks, the same intense pain in my elbows and I could not lift my arms.. So, I stopped eating bread and grains...and within a couple of weeks I was home free again. ...no more pain and I could easily lift my arms. I don't take pain medication...so I can try and remove pain naturally. There is a very good book on the subject: Dangerous Grains by James Braly M.D. and Ron Hogan, M.A. It says that over 200 diseases are caused by eating grains...from Arthritis to Schizophrenia.
Thanks so much, very accurate. I've been gluten free for 30 years, and almost completely grain free for 10 years, I just can't even digest it.
American Flour Made Her SICK, Here's How We Fixed it!
https://www.youtube.com/watch?v=ROeJd2TvOvY
American Flour Made Her SICK, Here's How We Fixed it!
https://www.youtube.com/watch?v=ROeJd2TvOvY
DMSO in combination with magnesium oil is a good combo for arthritic joints. You can find magnesium oil on Amazon. Amandha Vollmer wrote a book Healing with DMSO that has many remedies such as this. She also sells some of her remedies already mixed. I used her night cream and her scalp treatment. They are very good. You would learn a lot from the book.
Book and oil both ordered, thanks so much. When we share our knowledge, we can achieve so much.
Happy Body has a couple of creams that have MSM and CBD in them that I find help with my Rheumatoid Arthritis. I have also made some comfrey tincture that I apply with DMSO mixed with magnesium oil. I am not very good about applying it on a consistent basis.
You're very welcome, Duane. And i completely agree. Best wishes to you.
What are suggested ratios of magnesium oil and DMSO? Sorry if I missed it somewhere.
I mix mine with aloe vera.
Hey Duane, I have some experience to share with you, regarding your comments. For knees, elbows, shoulders... I have successfully, and repeatedly found using two capsules of the herb Horsetail daily helped me normalize in two weeks. A Neurosurgeon once asked me why my joints were so nice. It is slightly diuretic, and also improves A1C. Horsetail must not be taken fresh (raw) because it also contains nicotinic acid. Dried is perfectly safe. The active portion of the herb is silicic acid, the vitamin form of silicon, necessary for rebuilding connective tissue. Silicic acid is missing in Western diets mostly, I suspect... which would account for the very high rate of joint replacements. I avoided surgery on the acromion (in the shoulder) after one year of daily use, the shoulder healed completely. No notable side effects. SECOND POINT: Oral DMSO may also help the prostate, and I am guessing that the herb Stinging Nettle, combined with DMSO as a tea beverage would be very beneficial. I have used 1 tsp DMSO in 8 oz. water with no problem. I hope you find the cure you seek Duane. God bless you
Many thanks for your effort to reach out to help, we'll all improve ourselves this way.
DMSO's FDA approved version is known as Rimso, meant for instillation into the bladder. My M.O. is to get it as close to the target as possible. If that is not feasible, then internal routes are considered.
Figwort is an herb traditionally used for arthritis among other things.
"Regarding prostate inflammation and enlargement..."
You might try simply applying it externally all over the perineum.
Follow @makismd on X regarding using fendbendazole for prostate cancer
Do you have more information on arthritis being an infection and how to treat it? What about RA?
Wow, I've had so much information about this, but it's came in over many years and I don't have much to show my sources for this information. It is covered in the book, "Chronic" by Phillips and Parish. A short definition, a bacterium, or parasite, somehow invades our bodies, and where it's embedded, the infection causes a immune reaction, but this reaction goes into a auto immune reaction where our own immune system is now attacking our own cells at that location. Makes sense since only my right ankle and 4th finger and knuckle on the right hand have arthritis.
Have done that already. Might try DMSO Aloe. Arthritis is an infection, so the root cause is bacteria, parasites, lyme, etc.
Tried CD?
Actually yes, have 2 bottles and mix the 2 to produce 2 drops each to go in distilled water. Not sure it does anything.
OK, everyone responds differently. I did three three-week protocol and still do maintenance doses. Helped with arthritis in hips and lower spine, healed my shoulder injury,(although it took almost a year), helped my low stomach acid.
DMSO NOTES
Brother sprayed DMSO after applying castor oil on the perineum and improved urine flow and frequency, but also did CD enemas and ozone suppositories. DMSO alone has worked for headaches, bunions, burns cuts, scrapes. Added with magnesium to reduce muscle soreness and leg cramps. Added with ivermectin improved acne and acne scars. Tried oral but wife wont let me take it as per the odor…😂
I am almost 70. I took a fall recently when I was out getting some sun because I was reading an article on my phone instead of watching where I was going. I fell over and broke the skin on one knee (through my jeans, no big deal) but also banged up my right hand. It was really painful and I thought I would have problems for weeks. Had lots of pain in my knuckles and the first phalanges when I closed my fist or used my hand.
When I got home I rubbed DMSO cream into the back of my hand and then later used 70% DMSO liquid and rubbed it into the back of my hand and into my phalanges.
Now, a couple of days later I cannot feel any pain!
I will be carefully reading this article for other cures using DMSO.
Lol! That's great! I first tested DMSO on myself after I fell off my roof. Shortly after, I was a believer.
1) HAIR: what is the best combination for hair regrowth (other than finasteride)? Rosemary oil? How often to apply?
2) HRT: Have you heard of anyone using it with estradiol HRT cream (natural compounded cream)? And if so, do they have to lower their dosing? It is generally applied 2x per day indefinitely - is that disqualifying?
3) ECZEMA: used 70% gel with castor oil on my decades-old leg eczema and it healed it in one dose. (Notable that DMSO alone did not work. Had to combine with castor oil.)
Thanks for all your insights!
1) I listed them here. The most commonly used thing is either DMSO alone or DMSO with MgCl2. We've also seen certain chinese herbal formuals (I don't currently have access to) and injected exosomes be very helpful. Finasteride causes a lot of problems...
"Hair Loss and Scalp Health: MgCl₂ is often used to enhance DMSO hair restoration (e.g., with a spray of 10–15% DMSO diluted with 12% MgCl₂ is massaged into the scalp before washing or overnight). Additions like vitamin C, B12, sodium gluconate, rosemary oil or peppermint oils are occasionally included to enhance effects.
Note: thicker hair and reversed graying has been reported with DMSO, vitamin C, and L-lactic acid."
2) I haven't suggested it for estrogen, progesterone or testosterone because those already absorb with topical preparations, so DMSO is not needed and would make it much harder to ensure you were following the correct dose.
3) Thank you for sharing!
If you use estradiol , make sure you also use progesterone or it can cause cancer
Thanks for another phenomenally thorough article. A quick (albeit nitpicking) question, let's say you've applied DMSO to your joints 2-3 times a day for ten months. Then you want to try the DMSO/magnesium chloride combination, but you want to take some time off to offset any tolerance you've developed to DMSO over ten months.
Would two weeks be an appropriate waiting period for this purpose, or would a longer period (such as a month) be better? Thanks for any reply.
I really don't know, but my guess would be 1-4 weeks will be fine.
The main issue with tolerance is if it's for chronic pain and done every day.
All right thanks
"to offset any tolerance you've developed to DMSO..."
Can one develop a tolerance to DMSO?
I don't think I've ever heard of that.
Other MWD articles suggest not taking it over weekends, taking it the rest of the week.
Yes as Mouzer mentioned, the doctor wrote the following (in the June 21 article entitled "Therapeutic DMSO Combinations Revolutionize Medicine"): "With both topical and oral DMSO, people generally find that as time goes on, their tolerance to it improves. Conversely, if it’s used too frequently, a tolerance can develop, so it’s generally advised not to take it 1-2 days a week."
Personally I plan on hitting my wrist injury 2-3 times per day with DMSO/magnesium chloride for at least four months before reducing the frequency. Since I already used DMSO daily for ten months straight, I was looking for a ballpark hunch on how long I should wait to overcome any tolerance that developed.
What does the magnesium chloride do
The magnesium chloride improves the effectiveness of DMSO for some people in regards to treating scars, wounds, musculoskeletal issues, and other conditions.
Edit: You can find more details about magnesium chloride in this article.
For decades, I experienced mysterious, intermittent left eye pain, that could only be relieved by immobilising the eye, and sometimes only by also mobilising myself in an upright position. The pain contributed to regular severe sleep disruption.
Differential diagnosis was sinusitis, migraine, or some seemingly undiagnosable eye problem. Attempts to resolve included ophthalmologists, ENT, sinus surgery, analgesics, antihistamines, decongestants, migraine meds and eye drops.
In 2018, I started with an integrated medicine doctor and within short time, migraines, and sinus problems resolved. Still the mysterious eye pain.
2024 saw me cycle through three practitioners at a large, major eye specialty clinic. All they could offer was a diagnosis of dry eye, lubrication, steroids, and antibiotics. Finally, I got to visit them on a “bad day“ and they could see evidence of a past trauma in the eye with an oval shape. They only cause of that trauma that I could think of was a 1974 incident where a piece of glass from a broken fluorescent tube was lodged in my left eye for a couple of days. Their final solution this year was ongoing antibiotic drops and review in three months! No way! They didn't investigate DMSO when I offered AMD's info.
Three months ago, I started with DMSO at 20% in an isotonic saline, morning and evening, along with preservative free lubricating drops, I was getting the best pain management ever! Sleep improved.
I reduced this to once a day and when needed for pain relief. The lubricating eye drops were "semi-natural" according to Chat GPT. A Schirmer Test this week showed tear production in the left eye at 7. Previous high was 4. The right eye had always been above 10 which is considered healthy.
I have just started on more natural Oculocin eye drops(propolis, aloe vera, chamomile) co-administered with DMSO. I'll report back in a few months ! Thank You AMD!
There are a lot of medical specialities which would no longer be financially viable if DMSO entered mainstream use.
Go to a retina specialist to see if some is still in there maybe
This is absolutely incredible! Thank you SO much. What a resource!
This was the main thing I was working on for the last 3 months!
I am astounded at the research you've been able to compile. Not enough words to express my thanks.
Excellent. And, very much appreciated.
I'm trying to use it for a sudden scalp issue, extreme itching. But haven't found much detail about how to use it on your scalp so just using trial and error. Any advice?
And it sounds here like it would primarily be internal for treating lymel? Breaking down biofilms sounds great in theory, but usually breaking them down causes more herx symptoms.
1) Use a low concentration and then increase. Head is more sensitive.
2) With Lyme, it's normally internal. Like many other lyme things, you have to start with a low dose and work up to your tolerance. DMSO can help with herxing, as can zeta aid or lymphatic work, but most important thing is just not to dose too high especially at the start.
Might go without hair products for awhile. Especially if using DMSO. Many have no business being applied to the scalp. Several skin issues improve when chemicals are removed. Remember, the skin is reflective of the internal environment, and its a signal that something is awry. Dr. Hanes Ely had a very interesting theory on this.
Perhaps try Borax shampoo. The 20 Mule Team product from the laundry aisle. Re-use an old squeeze bottle, put in a few tablespoons of Borax, fill with hot water and shake a few times as it cools. It's okay if some powder is left unmixed. Apply to wet hair - it only lathers if the hair is dirty/has been a few days since shampooing. To rinse out, use a dilute vinegar rinse or citric acid (about 1/2 teaspoon in a cup of water - easy to keep a container in the shower to mix). May report hair is more curly after this!
Thank you. Can you explain the purpose of this? Is the Borax to clean the hair without chemicals, or because it has its own properties (like I know it is antifungal.) Vinegar is supposed to calm it, I believe. I did try it originally and it didn't work.
Borax removes buildup (from oil secretions, hair gel, etc.). Our scalps got in trouble when Hurricane Helene knocked out our water-to-the-house for a couple of months and shampoos were delayed way beyond the usual shampoo routine. Borax - more often than the once-a-week-Helene shampoo schedule - has cleared up various issues like buildup on the scalp. It's inexpensive! No worries about petrochemicals or artificial ingredients.
Thanks for clarifying (no pun intended!) My problem isn't buildup.
Last year I suffered terribly from scalp itching and eventually narrowed it down to drinking tap water (I am in the UK). Moving onto bottled water stopped the itching completely. I now use a water filter (just in a jug) which also seems to work really well. We have very hard water and a high nitrate concentration locally. My daughter also gets eczema from drinking our local tap water.
That's fascinating although I only drink RO water. But I suppose I could be getting nitrates elsewhere.
Scalp psoriasis?
Could be. Not diagnosed yet (waiting for dermatologist appointment) but I have an immune deficiency and immune deregulation, so it's possible.
Amahnda Vollmer published a book on DMSO with a scalp treatment with DMSO and some other ingredients. I don't think it would hurt to just make a 50% dilution with distilled water and spritz that onto your scalp. With eczema and psoriasis it is all about watching your sugar and refined carbs. But there is a fungal component too which DMSO will help kill off.
Just a warning: A MidWestern Doctor has advised not to use DMSO on dyed hair, just in case any residue is drawn into the body.
Consider the possibility of a low-grade histamine reaction or related mast cell activation MCAS. My scalp itched for years until I accidentally discovered MCAS was happening. Quercetin made the difference.
I do have MCAS and take a number of things for it (quercetin, perimine, etc.) Chat GPT just went through my supplement list and suggested ones to take out that might aggravate mast cells. But I will say this scalp thing came on instantly and has been constant for 3 months. Different than most MCAS which comes and goes.
I wish you all the best in getting relief!
I did early on. Also lemon juice, olive oil, salt scrubs, etc. Nothing worked. I was pretty convinced it was a fungus and my doctor gave me prescription antifungal shampoo. Which seemed to work at first but then made it worse over time. Now I've gone back to organic products with anti-inflammatory ingredients, also experimenting with DMSO and silver, and with essential oils. Hydrocortisone cream works. But I have very thick hair and it's really hard to get product onto my scalp instead of in my hair.
Have you tried high dose biotin? If it's seb dermatitis it could cure it. 40 mg (not mcg) for three months, then decrease dose for maintenance. Completely nontoxic, they give 200 mg to babies.
Following this thread as my son has been struggling for two years with a very stubborn scalp issue. I suspect folliculitis, but rhe doctor said the culture came back negative. It almost resolved after a round of antibiotics for another issue he had, but it returned in force. I've tried homeopathy, ACV, colloidal silver, changing to all organic shampoo, honey. I sent him to camp 2 weeks ago with a spray bottle of 50% DMSO combined with Lugols and colloidal silver. I hope he has had some success with it!
Try liquid coconut oil, rub into scalp, leave for an hour or so, wash out. Don't heat up solid coconut oil to get a liquid because it will re-solidify in your drains. Do every 2 or 3 weeks. A very soothing and healing natural scalp treatment is here: https://www.youtube.com/watch?v=jTI8ki67BK8
I need to know if DMSO is contraindicated for someone on blood thinners, specifically Eliquis. My 89 y.o. dad wants to use DMSO for various things, but I'm afraid to recommend it until I can answer that question. If the answer is nuanced we'd find a doctor for a personal consult but then...where to find such a doctor who would have the...authority, audacity...whatever, to find an alternative to Eliquis (if that's what was needed to be able to take advantage of DMSO)?
The observation within the DMSO community and the doctors I know is that it is not.
However, I have read 2-3 reports from readers who said they started having periodic nose bleeds on DMSO. Given all of this, the most prudent course is to start with a lower dose, monitor coagulation parameters (which is often done for anticoagulants anyways) and then gradually raise the DMSO dose.
Ok, just to be clear, is what you just said applicable to all methods of use, or just topical (concentrations and frequencies of application)?
Why is he on it? DMSO has anticoagulant properties and it could potentiate the Apixiban, however DMSO works on many fundamental issues that cause the need for blood thinners. Would have to be done very carefully. AMD has shed light on some of these issues, which may be correctable, specifically blood sludging, zeta potential and arrhythmias.
Yes, very good. So, he's got a history of a-fib, which I don't know if that is considered cured or not, now that he has a pacemaker. But the reason they keep him on the Eliquis now is because of his heart valve clip which is supposed to reduce some of the excessive backflow. Supposedly that device can generate clots. The "very carefully" part is why I would much prefer to find someone we can consult with who has a complete understanding of all the issues involved, as well as the...whatever it takes to go against what I would assume to be the conventional wisdom, or standard of practice, that the blood thinners (especially the ones that make someone some money) are what are keeping him from stroking out. Plus, as you might see, my own cynicism of conventional medicine is going to keep me from seeing things clearly as well. I've just been reading so much evidence of misconduct and deception there lately, that I'm almost inclined to do exactly the opposite of what they say is the truth, assuming THAT must be the truth. And then along comes DMSO (again, I suppose) and I'm maybe TOO ready to trust it as a cure-all.
I believe Dr Pierre Kory is now doing DMSO consults at his clinic.
Ok thanks, I've already found some other possibilities, but none confirmed yet, so I will add that to my list.
PS: I agree, the medical system is nearly complete bullshit. And I was skeptical of DMSO at first. That is until I tried it on myself, my wife and then my patients with amazing results.
So, not cured, but managed afib. He's on the Apixaban due to the risk of a thrombous, both from the fib and the clip. The clip you referred to is typically treated with 6-12 months of aspirin and plavix. Unless the interventionalist does Apixaban for unique clinical insight (cards is probably viewing this like an artificial valve which stimulate clotting). To my knowledge, I am not aware of an interaction with topical DMSO and Apixaban. The same is true with oral MSM which is the processed version of DMSO (essentially). Although there aren't a lot of docs out there using DMSO, let me know where you live and I might be able to put you in touch with someone. At your dad's age, regardless of weight or renal function, if he were my patient, I'd have him on 2.5mg Apixaban twice daily and if he wanted to use it orally, I'd check an anti-Xa lab exactly 4 hours after his first dose of the day. Not much you can do about the clip, but it makes sense to read up on Zeta potential and try to find a doc well versed in these approaches.
I sent you a direct message. Hope I did that right.
Feel free to recommend any Docs in TX using DMSO protocols, for patients.
Have family members who would prefer medical guidance due to their current meds. Thank you!
Me Jane, I just found out last week that my D.O. got DMSO in for IV's. Gonino Center for Healing, Heath, TX. Maybe this will help you, I don't have anymore info other than the fact he has it and is using it with his patients.
What part of Texas?
Did you see my DM? thx.
Sent message.
I'm curious also.
Do you know when you print this out it's 50 pages?
I spent 3 months on this because I wanted it to be thorough!
I don't know if thorough is the correct word, maybe "of epic magnitude"
To be more precise, I really just want to give this field the best shot it has to succeed and become something people regularly do, so I want to give it a really good start to grow/sprout from, which meant I couldn't cut any corners on it. I also find all of this absolutely fascinating which is why I tried to track down every single thing in existence about it.
Well done Doctor. This is a terrific resource. Many thank yous.
Perhaps magnum opus is applicable?
The phrase I was searching for
Doc, you always are. Thank you!
I have a binder full of AMD articles...
I'm trying to figure out how to print them. Impossible from Substack - how did you do it?
I would like to print it to save my poor eyes - i can't look at the screen too long. But I'm finding it almost impossible to do. Could you tell me please how you managed to print the article? Thank you.
I have a hemifacial twitch (for the last 10 years) that has spread from the right eye to the nasal labia area and now the chin (seems to be the trigeminal nerve). I have tried many natural treatments from Acupuncture, Chiropractic. and massage without much success. I currently have been using botox around my eye to slow the twitching (particularly bad when I lay down and try and sleep) but cannot use it in my chin. The neurologist wanted to do brain surgery as they thought they saw a nerve that was caught on the edge of a bone, but I will not consider that nor medications like Gabapentin. Is it your opinion DMSO could help and if so, what protocol would I use?
Shelly, I also have hemifacial spasms and been getting botox. I'd love to know if you find dmso or other things to help. Thanks. Elaine
Hi Elaine, I decided to take 1 tsp of 75% DMSO internally to see if it can help. I have only taken it for 5 days and have already seen a positive reaction to my arthritis in my knees and hips and a slight slowing of the twitching in my chin area. I still have heavy Botox in my eye area so I can’t tell yet. I won’t know until the current Botox wears off but the other improvements are so welcomed!
Shelly, I haven't tried that. I do have botox but it only helps a little bit. It's hard to find someone that's really good without looking weird! Are you a member of the Hemifacial spasms group on FB? According to them the only cure is surgery, but not always. I'm 80 so not sure if want to go thru that. If it's a nerve that's compressed I'm not sure how DMSO will help.
Hi Elaine, I am 70 years old and will not do the surgery. I do not do Facebook so am not part of that group. DMSO has proven to regenerate cells and reconnect neuropathways so I am willing to try and see...if it doesn't help, nothing has been lost and it is definitely helping my arthritis, so if that is possible (knees were bone on bone at last xray) then who knows what it can do for the hemifacial twitch. I have also seen DMSO heal wounds very quickly so if the nerve covering has disappeared due to the compression, perhaps it could help that...don't really know but I am willing to wait it out for a bit. Good luck and I will keep you informed if it does help!
Thanks Shelley. Just wondering - do you smell like garlic from taking it? I'm going to try it. Also, I think the nerve is compressed and that is why it's twitching. Then, ultimately the covering wears away. I'm on that list just to obtain info and experiences of other people. Not all opt for surgery as it's a serious one. I mainly just read.
Newbie here! What source do you recommend purchasing dmso? Thanks in advance.
Thank you once again for all your work on this topic! A combo I've been using, just because it made sense to me to try, is DMSO and Dr. Christopher's Bone & Tissue ointment. The later I've been using for much of my life to heal everything from skin wounds to broken bones. It's a salve with comfrey and other herbs. Adding DMSO by just applying some to the skin area I'm working on, and then rubbing the Bone & Tissue into the same area seems to increase it's effectiveness. As in skin heals even faster than I have been used to over the years using the same salve. I've used anything from 20% to 100% DMSO for this depending on if applying to something more sensitive like the face or less sensitive like the legs/feet. The Bone & Tissue salve also seems to counter any tingly/burny feeling the DMSO can create by it's self as I will feel that if using only DMSO, but not at all if applying the salve immediately afterwards.
I've also had the same experience combining it with other herbs like a calendula hydrosol. If applying DMSO to my face (in a 20% solution) I can still get some tingling that's not bad, but not really comfortable. But if I mist the hydrosol over the skin right after applying DMSO, that doesn't happen at all. I assume it also might help increase the skin benefits of calendula but I can't say I have anything measurable to report on that.
Dearest Midwestern Doc, I have a son who was in the Marines, he has chronic back pain and migraines, and developed Type 1 Diabetes at 27 years old. Nothing has helped him. I told him about DMSO and he read that it’s a problem for Type 1 diabetics. Can you advise what kind of complications and if he should avoid trying DMSO without medical supervision?
Type 1 diabetes issues anyone out there?
Thank you for the great article. I have been trying DMSO for a while to help with general well being.
Some experiences:
I struggle with fatigue/burnout and often feel my the back of my neck area tenses up easily. I have had some success by putting DMSO on that area, feeling that some "flow" is returned. My inspiration for this was from other articles where you mentioned the vagus nerve often getting compressed around here and the need for good circulation to and from the head, not least for sleep.
I also had the idea to put DMSO around the kidney/adrenal area on the back (very roughly), to see if it somehow could help support the adrenals. Sometimes I can feel like a constriction in them when overexerted or stressed. Perhaps the DMSO helps create flow around here too, because it does seem to have some effect and I haven't felt that constriction as much afterwards.
So overall some good effects. Had effects wane a little after a while, but trying to find the right amounts and ways for me.
Questions:
The only downside seems to be body odor. I don't notice it myself, but others complain. Seems to kick in fast and last pretty long for me, at least if I try to take it orally. Are there any ways to mitigate it?
Other things that have helped me are lithium orotate and KSM66, to name a few.
After reading this article I'm very interested in trying DMSO combinations. I just wonder about mixing things. Let's say you have a supplement you'd like to try with DMSO - can you empty capsules in concentrated DMSO at let it sit for a while, then dilute it to say 50-70%? After that apply it topically? Guess I'm wondering about how much to use of each when making a mixture.
I have used methylene blue at 15 mg per day to restore my immune system after it was crushed by the Johnson & Johnson COVID-19 vaccine. This process took about 3 1/2 months. That was a in 2021. I have been taking methylene blue at the same dosage every day since that time. Recently,thanks to the posts A Midwestern Doctor, Recently,I have been drinking 3/4 of an ounce of 99.995% pure DMSO liquid along with the methylene blue. The result is that very little methylene blue appears in my urine! I believe this is because the DMSO is helping methylene blue penetrate my body’s cells more efficiently!
I've been experimenting with DMSO for a full year now. Mostly topical application. I started with 1:1 mix of DMSO in high-quality olive oil, gradually worked up to 5:1. It knocks out muscle pain and bruising like magic.
The most striking result was a hip joint that was steadily becoming more painful - I was considering asking for surgery. (I'm 70.) I applied the DMSO-oil stuff 2x day for a couple of months, then also started eating collagen powder with my breakfast (5 g day). After 6 months, no more pain at all, just a hint of stiffness after sitting for a long time. So I've gone down to 2x week (still taking the collagen every day). Pretty cool experiment!
I'm also using it for varicose veins, and after a year of 2x day (with one day a week off), they are only slightly improved. But considering I've had this condition for 50 years (!), I'm prepared to be patient. Oddly, I've noticed that the progress comes in waves, and the 1-day break seems to contribute to that, not sure why.
More recently, I've started trying to cure my chronic rhinitis by swabbing it 1x day in my nostrils and soft palate (so that it trickles down my throat). I put up with a brief burning in my nose, and an awful taste, but it seems to be working.
I thought I was being adventurous, but this article has so many more options I see I've barely scratched the surface!
PS - forgot to mention, this mixture also cured a TMJ problem that was deteriorating. This was originally why I first bought the DMSO.
And I do mean "cured" - my jaw went from a painful locking habit on one side (often while I was asleep - very disturbing!), and pain when biting into food, to totally normal functioning again.
That took around 6 months, applying the DMSO 2x day to the joint and along the neck tendon near it (behind the ear). Somehow they seemed to work together.
Please, one question, for persistent migraines, the combination of DMSO with castor oíl and cayenne pepper is topical or oral?
that one was topical
Dear Sage MWD,
I have been fascinated by your posts and I'm delighted to tell you that the last three weeks I have been using 50-50 99% DMSO with normal saline with 12% magnesium chloride in a nebuliser for five minutes each day. The results have been spectacular and I have stopped using my Ventolin puffer which I was using up to 12 times a day. It is really an extraordinary result. As a physiotherapist I am gobsmacked. I would like to include glutathione but my compounding chemist is unwilling to suggest a dosage to be added to my combination above. Can you please suggest one, for which I would be eternally grateful
1) Read the nebulized glutathione section here:
https://www.midwesterndoctor.com/p/dmso-heals-the-lungs-and-cures-chronic-35a
2) In the case of asthma, we haven't use glutathione so I'm not sure if it would have any value in your situation.
Maybe I’ve overlooked this information, but how often is dmso used? I just got a 70/30 to start and used it the first time yesterday. Stiff neck and low back pain are definitely improved. Applied again this moving I still have soreness even though overall better, but how much is too much? I don’t want to go overboard, but honestly, this is the best I’ve felt without nsaids for years. Is twice a day normal?
There aren't clear guidelines. It's ultimately whatever gives the best response for you and you have to experiment to see what that is.
Thank you so much for your reply. And thank you for all the work you are doing with this Substack. You are truly changing lives. God bless you, Doctor.
Wow! Thank you! Like drinking from a firehose!
Quick question.....My nebulizer bowl is plastic. Do we think it's safe to nebulize DMSO in it?
If DMSO is at a lower concentration and you've pre-cleaned it with concentrated DMSO (to extract the easily extractable chemicals).
Wow. Grateful for this compilation.
I used essential oils of turmeric and frankincense one drop each combined with DMSO gel when I started treating my knee inflammation and swelling (from old ski injuries and minescectomy) with excellent and fast results, after your first series of articles on DMSO.
This has opened the floodgates of my imagination for a number of future combinations to try.
Thank you every time!
Excellent article! Hey Doc, does purifying DMSO liquid to be odorless affect its effectiveness?
It has been mentioned that DMSO can treat nerve pain. From a hip osteotomy in 1984 the femoral artery was ruptured and pressed on femoral nerve. Artery repaired but left me with severe pain/injury of the nerve. I have not so good circulation in my leg all this time later with still some nerve pain. How best to treat this with DMSO? I posed the question in the comments earlier about taking DMSO internally with hip implants. Will this cause complications?
I have another question on DMSO. My brother has some kind of severe fibrosis in his lungs. Can barely walk to the mailbox. I saw the video of the guy with COPD that put DMSO in his inhaler SOMEHOW. But it doesn't describe exactly how to do it. Does anyone know exactly what the procedure is for this? Like, HOW do you do it?
https://www.midwesterndoctor.com/p/dmso-heals-the-lungs-and-cures-chronic-35a
I'm reading the comments and the article, but my problem is finding exactly how to mix things. I have a rotator cuff problem in my left shoulder (already had surgery on the right shoulder). I'm mixing 50% DMSO and 50% magnesium oil, put it on the shoulder every night. Seems to be helping a little. I'm reading here about MSM / DMSO. How about just putting a glucosamine/chondroitin/MSM pill contents into the mixture? OR I could buy bulk supplements MSM powder.
Everything I know is here (including the MSM mixture). If you want to try things beyond that you have to experiment.
Has anyone here experimented with combining DMSO with peptides? For example BPC-157 is on the upper edge of the size DMSO should be able to transport through the skin. I am thinking about topical DMSO/ peptide combinations as an alternative to subcutaneous injections.
I have heard a lot of people float this idea but have not found anyone who tried it.
I just saw a company that is marketing a sports recovery cream that contains DMSO, BPC 157, TB 500 and MSM in organic aloe vera gel. Interesting to see people formulating.
Great idea! My husband is going to try it so he can surf again. He broke his hand and it’s just so painful.
Mixing DMSO with glycine and NAC and/ or with R lipoic acid and acetyl l carnitine could be used to treat old age.
https://pubmed.ncbi.nlm.nih.gov/35975308/
https://www.pnas.org/doi/full/10.1073/pnas.261708898
Hi! First of all thank you so much for this. Thanks to you, I’ve been using DMSO to shrink large varicose veins on my legs - while they’re still present, they’re much smaller, softer, and a sensation of “thickness” that was present before is no longer there! I’ll share a before and after once they’re gone or almost gone.
A few questions for you. Do you see any potential benefits or detriments to taking DMSO orally while doing an extended water fast (eg 48-72 hours)? My initial thinking is it would help with healing while the body has more capacity from having a break from demanding metabolic activities from digesting.
When measuring out DMSO for oral consumption, is it ok to use stainless steel measuring spoons? I’m fairly paranoid about inadvertently getting anything harmful into my system from all the warnings.
For applying herbs and roots (eg ginger and turmeric), would you recommend using a powder, juicing fresh roots, or buying a tincture with an extract ?
Many thanks!
1) It's advised to take beforehand, not sure if it's good bad or neutral during the fast. My guess would be if you are less sensitive, it's good (bc you will do a deeper detox) whereas if you are more sensitive, its too much).
2) Yes that's fine.
3) DMSO will extract the herb, so you can mix a fresh herb or a powder with it and let it soak for a day.
thank you!
Definitely agree that this is the most comprehensive article yet! Thank you very much for aal that you do and contribute AMD! I was wondering about the following. In March of this year I underwent stem cell therapy on both my knees for osteoarthritis Grade IV. So far, it has worked wonders, i can walk stars without any pain and can go on a brisk walk of 1 hour on flat, frim terrain. Every night I have been rubbing Andiroba and its sister oil Copaiba on them, and it seems to be enhancing the work the stem cells have been doing, lessening inflammation and promoting cartilage healing. I was wondering, haven't experimented yet, if applying a layer of 70% DMSO on top of the oil blend would be safe. Would you please be able to give some advice on this? Much appreciated, many thanks. L.C.
I am not familiar with those oils
I am curious since DMSO is also a substance transporter, is it best used with purified water and on an empty stomach? I realize the article says 1 tsp with water slowly after a meal but what if any toxins in the food such as hormones or antibiotics in meat or glyphosate from farms? Am I overly concerned?
This hasn't been an issue for people, but ideally:
•mix with purified water.
•consume an hour or two away from anything potentially toxic. This is more in regards to pharmaceuticals than junk food.
Thank you.
Overly concerned, but good thinking. Its wise to consider this. I probably wouldn't want Mcdonald's running rampant through my system, potentiated by DMSO.
Also, my husband has chronic sinus infection... he uses a nasal spray daily. Is DMSO something that could help here? He would like to be less dependent on that spray...
Ellen, has he tried "Snoot!"?
It's a commercially available Chlorine Dioxide nasal spray, and very effective.
I second this! Its a great way to introduce people to oxidative therapies.
Just ordered it! TY!
Yes.
When I had a sinus infection I rubbed it directly onto my face. It was 100% strength and it did leave me with skin irritation but my sinus pain was gone in minutes.
Wow that's great to hear!
Some folks find relief with a 10-20% DMSO solution first, followed by CDS and/or glutathione, netipots, xylitol. Some suggest ozone held in the sinuses.
I've used DMSO + colloidal silver and that works great. Snoot is good too.
Same here. Problem is how to get medication way up into the sinus labyrinth. I use a nebulizer that atomizes the medication, still not sure it goes all the way into the sinus parts.
Nebulizer is the way.
Can you comment on how to use DMSO to get rid of toenail fungus? That would be SO great!! Thank you for this post!
It's in here.
That was covered throughout this article and to a lesser extent in this one:
https://www.midwesterndoctor.com/p/dmso-transforms-the-treatment-of
Drinking H2O2 can be quite helpful for fungal infections but that is too strong and can damage the intestines.
Doc writes in this article..."when drinking H2O2 use 10-20 drops of 3% in a glass of water with DMSO". Use 1-2 times/day AWAY from meals ( 30 minutes before or 3 hours after meals).
Might anyone know why, having put DMSO on my gums one time, my onmly tooth with a filling is sensitive?
Secondly, is there any info on how DMSO may affect (healthy) lipids?
Thank you
An idea for skin things... 50% DMSO + 50% H2O2 (hydrogen peroxide 3%).
Dear Dr.
I am a paid subscriber and love your research!
Could DMSO help eradicate a small squamous cell carcinoma on my forehead?
My dermatologist set me up for Mohs surgery in 2 days.
Thank you!
What about using DMSO orally to reduce BPH and nighttime urination issues. Is there any dosage protocol that has been shown helpful?
"DMSO: A Mixed-Competitive Inhibitor of Human Acetylcholinesterase"
The above is the title of a PubMed study. I wanted to ask if this means that DMSO has anticholinergic effects-- the same as anticholinergic drugs that older people are cautioned against taking because of possible cognitive downsides, i.e., on memory and risk of dementia.
I have questions regarding the use of dmso. I have purchased the product but need instructions for the use of it with saline and the proper nebulizer.
Any recommendations for dmso mixture for mother in law with resistant infection after knee replacement surgery that didn't go well? She's 82.5 years old, in incredible pain and the doctor's haven't been able to rid of the infection even after a second surgery to help "clean out" the knee and infection!
I've had a chest problem since 2016.
Due to the "advanced" medicine in my home country of Macedonia and my weight at the time, no doctor took an X-ray, let alone a CT scan.
In the end, I got an X-ray on my own, and the result was emphysema. Officially, I was told there’s no help for me, so I started looking into unofficial options to see what’s out there.
I engaged GROK from X, and it started finding some things.
To keep it short, I’ll write what I’ve been using with no effect—maybe I’m not dosing correctly.
If anyone wants to help, please do, because I’m at the end of my rope. I nebulize 3 ml of DMSO (50/50 ratio) twice a day.
I nebulize 1 ml of liposomal glutathione (containing 55 mg glutathione) twice a day.
I nebulize 15-20 drops of propolis once a day.
And sometimes I nebulize 3% hydrogen peroxide diluted in a 2 ml hydrogen to 10 ml water ratio.
I've had a chest problem since 2016.
Due to the "advanced" medicine in my home country of Macedonia and my weight at the time, no doctor took an X-ray, let alone a CT scan.
In the end, I got an X-ray on my own, and the result was emphysema. Officially, I was told there’s no help for me, so I started looking into unofficial options to see what’s out there.
I engaged GROK from X, and it started finding some things.
To keep it short, I’ll write what I’ve been using with no effect—maybe I’m not dosing correctly.
If anyone wants to help, please do, because I’m at the end of my rope. I nebulize 3 ml of DMSO (50/50 ratio) twice a day.
I nebulize 1 ml of liposomal glutathione (containing 55 mg glutathione) twice a day.
I nebulize 15-20 drops of propolis once a day.
And sometimes I nebulize 3% hydrogen peroxide diluted in a 2 ml hydrogen to 10 ml water ratio.
I started reading the DMSO articles in 2024. I purchased some from the DMSO Store and have had a couple experiences using it. While nursing I got mastitis, and it didn’t work topically. I had to resort to antibiotics, unfortunately. However, I did use it to effectively eliminate an inflamed alopecia spot on my scalp. First time with full hair regrowth without the use of injected kenalog!
Am I missing something? I cannot seem to find the recommended brand to buy ? Everytime I click on a link it brings me to another article
I have 100% solution. Would it be better to start with 70%?
Also, I take a lot of supplements. Are there supplements that DMSO should be taken at a different time of day from them?
Thank you for what you do!
For using in the eyes it says 3% isotonic solution. Does that mean 3% dmso mixed with the rest being normal saline? Not sure how to achieve this 3% solution. Could someone please help me?
Yes. 3 parts pure DMSO, 97 parts saline.
Thank you very much!
I’m struggling to know how to make the eye drops for cataracts. Can someone please explain it to me? Thank you so much.
I really appreciate the amount of detailed information here! I'm just learning about DMSO and this is super helpful! Any information on using DMSO to heal (or shrink) uterine fibroid?
AMD could you review this article re the risks of DMSO please? https://orthomolecular.activehosted.com/index.php?action=social&chash=eba0dc302bcd9a273f8bbb72be3a687b.413&s=c6452938e33bb04f33c94a00f13724bf The Double-Edged Sword of DMSO: Healing Agent or Mitochondrial Damager?
1) He's citing in vitro studies not animal ones where it was held a high concentration for a prolonged period.
2) In the body it rapidly diffuses and is at much much lower concentrations.
3) Many studies show the opposite.
4) People on DMSO report an improvement of fatigue not worsening.
5) DMSO has been repeatedly shown to protect the mitochondria from stress and maintain their function when their environment is compromised.
This just came across my desk. I wonder if AMD has seen it yet?
https://orthomolecular.activehosted.com/index.php?action=social&chash=eba0dc302bcd9a273f8bbb72be3a687b.413&s=b19dc9065897f1ff17a0617fe3ac53b1
It rapidly dillutes once put into the body
Hi, I have just subscribed, live in the UK. The DMSO products recommended via links are not available to me due to location. Can you advise me of any UK suppliers that are reputable please?
I do not know the UK suppliers, but the top rated ones are probably fine.
I will do some research, thanks
I notice that you recommend Medicine Girl's substack. She seems to be against DMSO-she has an article "Disasterous DMSO" on her substack. Do you have any comment on her stand against DMSO?
Where did I recommend her (if I am I would like to cancel it)? I think her info is highly erroneous. She essentially posts that every natural therapy people benefit from is deadly poison, attacks everyone who supports them as a pharmaceutical lackey, and then posts a lot of erroneous and incomplete information to justify her position.
We've tried to reason with her on a few topics and concluded she was either refusing to change her position because she wants traffic by creating controversy or because she is being paid off to torch off-patent therapies (I lean to the former, a lot of others lean to the latter).
Regarding her stance on DMSO, it fits the pattern of what she's done an other therapies. Most of the article was incorrect or extremely misleading, she refused to correct anything when given information (either now or on previous versions of it) and while most of the commenters had very positive experiences and no issues, she told all of them their experiences for one reason or another didn't count.
I hope someone can help me. I am having an allergic reaction to a combination I used and nothing I try helps the hives and intense itching.
Day 1: I fell and twisted my ankle and left knee very badly, also strained my right knee (I have arthritis in both knees.) I rubbed the foot, ankle, leg, and knee with Herbal Mana Frankincense DMSO Gel, and also rubbed the right leg and knee. I was amazed to get relief. I continued that protocol morning and evening until Day 3. On Day 3, there was significant bruising and swelling on the left foot, although no pain, just mild soreness. On the evening of Day 3, I showered, and applied Arnicare Cream, waited 10-15 minutes, and applied the Herbal Mana gel on top of it.
By the evening of Day 4, I developed hives and itching on both legs where I had applied the Arnica Cream and Herbal Mana Frankincense DMSO Gel. Benadryl gave me no relief. I started Zyrtec and Pepsid. Also 1 gram of Vitamin C every 2-3 hours.
Days 5-10: The whelps and rash were only on the areas where the cream/gel were applied and did begin to diminish, but the intense itching did not. I've used aloe vera gel from a plant, benadryl cream, cortisone cream, witch hazel, coconut oil (not all at the same time). Nothing has given any relief.
Day 11: Whelps began to appear on the upper abdomen and inside lower arms, then around my neck and chin. Itching is intense. Had taken Zyrtec in the am, took 50 mg Benadryl at bedtime. No relief.
Day 12 (today): This morning, whelps are developing on my face.
I have been afraid to use DMSO again, although I feel that the culprit must have been the inactive ingredients in the Arnica cream. I do have a bottle of DMSO pure pharma grade 99.995% from the DMSOSTORE and have gotten distilled water. Would I dare try drinking a weak dilution or rubbing it on the hives?
I am able to walk without pain, although the left foot and ankle are still swollen and may be bruised under the red rash.
What you are describing sounds like you had an allergic reaction to arnica (which is known to happen to some people) and DMSO may have enhanced that by bringing it into the body.
Main priority is to completely avoid any arnica products, stop the topical things, and to be on the watch for if it seems like the allergic reaction is spreading to the throat (as at that point, you will need steroids to prevent an anaphylactic reaction). Given that it's spread to your face, that is a possibility, so I would try to see a doctor as soon as you can rather than once you start to notice swelling around your throat.
There are a variety of home remedies which can help with the itching (ie. standard process Antronex, cooling the affected areas), but I would advise seeking out medical help to avoid the risk of anaphylaxis.
I hope someone can help me. I am having an allergic reaction to a combination I used and nothing I try helps the hives and intense itching.
Day 1: I fell and twisted my ankle and left knee very badly, also strained my right knee (I have arthritis in both knees.) I rubbed the foot, ankle, leg, and knee with Herbal Mana Frankincense DMSO Gel, and also rubbed the right leg and knee. I was amazed to get relief. I continued that protocol morning and evening until Day 3. On Day 3, there was significant bruising and swelling on the left foot, although no pain, just mild soreness. On the evening of Day 3, I showered, and applied Arnicare Cream, waited 10-15 minutes, and applied the Herbal Mana gel on top of it.
By the evening of Day 4, I developed hives and itching on both legs where I had applied the Arnica Cream and Herbal Mana Frankincense DMSO Gel. Benadryl gave me no relief. I started Zyrtec and Pepsid. Also 1 gram of Vitamin C every 2-3 hours.
Days 5-10: The whelps and rash were only on the areas where the cream/gel were applied and did begin to diminish, but the intense itching did not. I've used aloe vera gel from a plant, benadryl cream, cortisone cream, witch hazel, coconut oil (not all at the same time). Nothing has given any relief.
Day 11: Whelps began to appear on the upper abdomen and inside lower arms, then around my neck and chin. Itching is intense. Had taken Zyrtec in the am, took 50 mg Benadryl at bedtime. No relief.
Day 12 (today): This morning, whelps are developing on my face.
I have been afraid to use DMSO again, although I feel that the culprit must have been the inactive ingredients in the Arnica cream. I do have a bottle of DMSO pure pharma grade 99.995% from the DMSOSTORE and have gotten distilled water. Would I dare try drinking a weak dilution or rubbing it on the hives?
I am able to walk without pain in the left foot and ankle, although it is still swollen and I suppose bruised (the red from the hives/rash covers the bruise.)
Thank you for all your research and time. You are a gift to us all 🙏
I do have a question that I have not come across an answer for yet.... can DMSO be ingested or even applied topically if I have an implant, or a metal screw or a plastic mirena etc??
Doc, you and Dr. Mercola have expounded on the many uses of DMSO and I was impressed enough to buy some; however, I read another SUBSTACK article explaining that DMSO is a waste product of the paper industry and a solvent. The MSDS lists it as a hazardous material. Can you address the possible risks of it? I want to be fully informed.
She keeps posting that to get traffic. It's highly inaccurate, but each time we try to explain (along with dozens of readers who have tried as well) the specific points, she says we are brainwashed by the medical field and don't understand what we are talking about since anything else cost her views and refuses to correct anything (along with telling everyone who says DMSO helped them a lot and had no side effect that their experience, for one reason or another, doesn't count).
Her brand essentially is saying commonly used natural therapies are actually toxic and you need to just do detoxs and elimination diets. When I looked at her arguments, I realized that she was juxtaposing common issues with other pharmaceuticals onto DMSO (which is a common thing people do, as due to it being hard to fully understand a subject, they always juxtapose their pre-existing knowledge base onto it).
Regarding the deaths, the points she's omitting is that in all but one of them, another product was involved, as on FAERS if someone has a lethal reaction to a drug, they list all the other things they were taking as well, and in those cases, it was more likely culprit of death, and in many cases, they were being given intravenously (where a higher risk of death, particularly the onyx cases where the DMSO polymer mixture was being used to patch an otherwise fatal internal bleed and hence was a high risk situation). When I wrote the safety article, amongst other things I read through all the FAERS reports and explained them, no one else has done that. Conversely, most medications have thousands of deaths in FAERS, many of which can be directly attributed to the drug. The fact that over roughly 40 years 21 deaths are in there almost none of which can be attributed to DMSO is an insane safety profile. The primary drug DMSO replaces (NSAIDS like ibuprofen) are well recognized to kill hundreds of people each day, and their toxicity is rarely discussed.
In short read these two article, critically compare them to hers and then make your own decision:
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety
https://www.midwesterndoctor.com/p/the-fdas-war-against-dmso-and-america
Thank you for this amazing resource! This will help so many people.
I would like to try DMSO as an eye treatment and experiment to see if it can reverse presbyopia.
Has anyone used DMSO in their eyes after Lasik surgery? I had Lasik surgery about 15 years ago and was curious if I can still use DMSO eyedrops in my eyes (diluted of course).
I'm intrigued with the possibility of combining DMSO with laetrile. An on-line search suggested that the maximum safe dose of laetrile is .37 mg/kg body weight. I weigh 73.5 kg, so using this formula my max safe dose is about 27 mg. One can buy derivatives of apricot seed capsules on-line, but they typically contain 500 mg of apricot extract. How would one reconcile this?
Also, how do I locate replies that are posted?
Berberine has been shown to be an incredible cancer therapy targeting multiple pathways. But bioavailability is challenging. Could it work with DMSO, perhaps topically?
Hi! Back is now essentially pain free after about 2 months of regular use. Was using a 70/30 DMSO and aloe vera gel mixture on hip, si joint and hamstring injury. Was using with magnesium oil, peppermint, lidocaine cream, & arnica. More recently, an 80% solution with peppermint oil has also been great and it dries much faster than the two with no residue. However, we are finding that my clothes are carrying the scent after laundering. I usually try to make sure I'm dry before putting on clothes but am wondering if there is a residue causing the issue. What detergents are working for others to get rid of the smell? My husband is complaining and I don't want to give up my pain relief!
An idea: Vinegar is very good to remove residues, and as a presoak.
Fill washer with water, hypoallergenic laundry soap, 1-2 cups vinegar (5% acetic acid), let soak for a while, 15-30 minutes. run wash cycle. When filling for rinse add 1-2 cups vinegar. I run 2nd rinse cycle, add 1-2 cups vinegar, done.
I can't help but wonder if Dr. Mercola and the "Midwestern Doctor" aren't one and the same. I'd been suffering from "arthritis" in left hip. From my reading, DMSO doesn't seem to be reliably effective in the case of that large joint or much of anything below the waist. But. I've been applying DMSO full strength in addition to physical therapy and feel like I've gotten some relief! At least one of my children tell me that the "placebo effect" can be quite powerfull. Whatever!
I wish I could make more of a commitment than "monthly" I'd begun following Dr. Mercola at end of 2019. I was particularly enhusiastic about his insights after he was on the Governments short list of disinformation providers. I fell out while he continued to speak in terms of viruses. I read Virus Mania in 2020. I also support Westin Price and the Baileys. I think it must be difficult when one is in business as Dr. Mercola clearly is to change one's position on "Germ Theory." This is why , I can't help but wonder if Joseph isn't "The Midwestern Doctor" I guess this would be like unmasking "Batman." I folowed the "Root Cause Protocol" after being introduced to it by Dr. Mercola; until
looking into their un supported suggestion to look into bio magnetism. Ied me to study it and found the diagnosis revolved around treatment of various named "virus" and "parasites" I am on board with magnetic therapies to the extent that thay encourage blood oxygenation and thus ph and resulting blood alkalinity. Too much to say here! I also appreciate Mercola's advice on EMF exposure and am a longtime student of Victor Schauberg and structured water. Bravo!
What has the DMSO community found for treating the neuro-autoimmune injuries associated with vaccines (ex: Guillain-Barre, CIDP, etc.)?
I cannot find the post that shows how to use DMSO and in what mixture for various ailments, and where to get it. Please help
Any risk of taken 40 ml diluted in 500 filtered water 70% DMSO. By accident it was taken
Good morning, I'm an Italian reader from Verona. I'd like to know if DMSO increases zeta potential. Thank you.
In my case, without any prior knowledge of this wonderful paper, yet with some input from the ongoing stream of useful papers from AMD, I have followed the discovery of Dr Paul Makis, the discoverer of his 80% successful cure for Sepsis, intravenous vitamin C combined with Thiamine, (vitamin B1) and hydrocortisone, I had already made a solution of 50% DMSO with distilled water, and then added 100g of vitamin C, later increased to 200g, and then as I had a small quantity, 10g, of Vitamin B1, I added that as well. The use of which has produced some very interesting results. As of now the bottle has to be shaken to distribute the contents, and I am going to continue to take a teaspoon every day diluted in a glass of water.
Again, having also discovered the video conversation; Dr Adis - The Antidote, I am already using Nicotine patches, but now wonder if the addition of a similar dose of Nicotine would make the nicotine patches redundant. There are so many possibilities, and we can be sure that a new industry will arise from our expeditions into the associated original thought progress.
DMSO use having had replacement lenses fitted to treat cataracts. Would topical, nebuliser or systemic use affect the plastic lenses? I have auto immune issues I’m trying to treat.
Can anyone please tell me where I can purchase DMSO that is pharmaceutical grade enough for nebulizer and oral routes? I’ve heard most of it listed on Amazon is junk. Thank you.
TT, AMD recommends dmsostore.com.
My experience
- AZ - Aloe/DMSO cream (70/30) - works as described - no side effects
Used on my sore shoulder.
- DMSO store - Aloe/DMSO gel - no warming effect and causes my skin to itch.
- AZ- Liquid DMSO - 1tsp/day with filtered water ( did not know about DMSO store at time)
-- Pro - my hair got softer , my weight stabilized (not overweight), skin felt better softer.
-- Cons - I developed joint pain at the top of my legs, quit the DMSO liquid
(apparently what I bought was supposed to be Pharma grade but it may not be based on other comments I read)
Pain is diminishing after stopping.
I am wondering if the DMSO liquid "released heavy metals" already in my body as my symptoms do coincide with heavy metal toxicity.
Still researching on that topic.
Hey sub cat. Thanks a lot for your reply. I’ll check out the info. Is “AZ” an online store name?
AZ = amazon ... sorry for the late reply..
I'll ask here, and if not seen or nobody able to answer, will post again on the next article on DMSO. Thanks. Evidently the clots from the shot do not break down enough and would not show up on a D-dimer test. Three questions please: other than live blood analysis (if that does show the clots), and an esoteric TEG test, how would one know that they are in the body? How to break them down (is Nattokinase effective)? And will applying DMSO to the carotids still work for someone who has a stroke from a spiked clot??? Thank you AMD and/or to whomever can answer.
neprinol afd is the best solution we've found so far
Wow. You saw it. Thank you. Is neprinol afd to break down the clot or to use apply to carotids if someone has a spike induced stroke instead of DMSO?
Gradually break down the clots.
I am recommending Neprinol AFD to friends who have had strokes. (and to anyone who will listen) Is it accurate to say that regular anticoagulants and tPa do not break down spike induced clots???
TPA might but that is not something that would ever be used in that context (it's more for things like if you have a stroke and show up at the ER)
Yikes. You saw my question again. I oughta buy a lottery ticket and split it with you : ). Thank you.
Bless you!
Where is there info on using dmso for pets, specifically cats? My cat just developed asthma and I understand it's great for humans. What about cats? He's an 18 lb mixed Maine Coon and he won't take anything orally. Clipping his nails takes two strong people, lol! Thank you!
Question:
Can I use procaine or lidocaine together with DMSO for subcutaneous paravertebral injection against/for spondylosis and hip dysplasia?
My 10 year old MaliDutchi has existing or developing spondylosis all over her lumbar area.
I would be most grateful as well if someone can point me some literature as well. 🙏
That is discussed in the previous article.
https://www.midwesterndoctor.com/p/therapeutic-dmso-combinations-revolutionize
Ad no 2, I found these"
https://www.calpaclab.com/dmso-safe-acrodisc-syringe-filter-with-nylon-membrane-0-2-um-pore-size-25-mm-diameter-sterile-pack-of-50/pall-4433?srsltid=AfmBOooPKIKovpQ2oadDKf7pQpRBzXFofs163_8ApsnCS80EvlaQIG7E
In case someone is looking to do something similar.
Yes. I read that. That is the main reason I am interested 😉
1. I am wondering is a combi injection of procaine and DMSO more painful than procaine alone?
2. would this fit your wording "run it through 0.22 μm filters with DMSO compatible housings": https://www.amazon.com/Diameter-Hydrophilic-Filtration-Non-sterile-COBETTER/dp/B0B7BLCYXY ?
Thanks.
Another excellent article. Thank you you.
You mention the use of Prostatilen for treatment of BPH. Where can I get the 30 mg one that you recommended from? Is there anyone out there who has used this and has some experience?
I cannot thank you enough for your incredible research. A good friend who has suffered for decades with an autoimmune condition finally relented a few months ago and is now on Enbrel and Methotrexate. Would she need to stop these drugs before trying DMSO? I've seen your research that DMSO can be used diluted on its own or in combination as an efficacy enhancement with lesser doses of other drugs, so I'm not sure how to help her navigate this. It's so difficult when the doctors and specialists have no clue (and don't want to have a clue!) about DMSO.
In the section on DMSO in Veterinary Practice specifically severe dermatitis involving feet and nail beds are there articles I can get links to. I’ve tried following the links in the references but it’s not getting me anywhere. I’ve just started the treatment this morning by mixing in equal parts DMSO + Nitrofurazone & Nystatin. I was hoping for more specifics from that particular reference of 9 cases. We’ve had very little improvement early on with typical vet treatments and his condition seems worse. When reading blogs people repeatedly saying the same that they try everything but no results. If there is any more information please share.
Does anyone have the protocol for using DMSO for hair replacement? I read the articles but I don’t really see a protocol.
Doc, I understand that DMSO absorbs through all seven layers of the skin, and carries other substances with it into the bloodstream. My question is, does it penetrate the cell walls and enter the cells? I have very high serum B12, but low Intracellular B12. I have been searching for a way to get B12 into my blood cells. Can DMSO possibly be the answer?
I do have one coy of each (677, 1298) MTHFR genetic SNP. My father had pernicious anemia. I have neuropathy so severe that most of my body, including inside my mouth, are completely numb. I believe this is a B12 issue. Has anyone ever considered injecting DMSO? I am taking it internally, but it bothers my stomach somewhat.
In the book “The 85% Solution: MTHFR is Overpowering Our Medical System- - Chances Are, You Have It Too”, by Dan Purser MD, in chapter 3, it states:
“You can become toxic with high folate or high B12 levels, i.e. your body will have problems converting inactive forms of folate and B12 to the active forms. So the inactive folate or B12 will simply build up in your serum, also inhibiting the active forms.”
Your thoughts about this would be greatly appreciated
I just wanted to share my experience in support of this article.
For over a year, I dealt with what appeared to be eczema on the inside of my right ankle; about a two-inch square patch. The itching was relentless. It would keep me from falling asleep, wake me in the middle of the night, and drive me to scratch just to find some relief.
I tried everything: prescriptions, over-the-counter creams, and natural remedies. Nothing worked. No doctor I spoke to could offer a solution that made any real difference.
Then I found the undiluted DMSO roll-on from the DMSO Store. I applied it two or three times a day for about a month. The itching started to reduce, and after another month, the rash completely disappeared. The skin in that area looked a bit like a prune for a while, but the itch was gone!
I’m incredibly grateful. Thank you, Midwestern Doctor, for spreading this knowledge. DMSO changed my life.
Great article! 👍 Thank you Doc! If DMSO helps cure athletes foot, can it also be used to treat toenail fungus? Has anyone have experience with it? 🙏
I consider myself to be well-read on health but since finding 'aMD' via the Vigilant Fox. I am so humbled.
My experience with DMSO so far.
- ordered 70/30 (with Aloe) and had limited but positive results treating a damaged rotator cuff. I absolutely love the vivid dreams. Been using it over 1 week.
- ordered the liquid 99% and tried in my morning coffee with heavy cream, results an 'explosion' but I have no gall bladder.
- I moved to ~ 1 tsp with water and water as a chaser.. omg that stuff is really strong !!
- day 2 moved to 1 in the morning and 1 about noon.
- Edit: now doing only 1 tsp with water chaser.
I am noticing a big improvement with my shoulder. I am still going for an MRI to see if surgery is needed but based on my past 3-4 days I am thinking not.
My regiment is cream on my shoulder and 1 tsp/day. As 'aMD' has stated Everyone is different so start slowly and adjust. I am so thankful that I am in the 80% and pray for those in the 20% find a solution.
To close, in my experience with a clean diet and good health DMSO has been a very positive experience for me, I do not take any meds other than NP Thyroid.
Peace be with you in your journey.
cant find "aMD" substack. can you give more detail on this person?
T Jay - aMD is my abbreviation for "A Midwestern Doctor".
I haven’t had time to read this article yet, but I saw something earlier today where they said I’d be very careful with DMSO because whatever contaminates, residue on your skin will absorb right into your bloodstream.
A dear friend has severe trigeminal neuralgia, as well as either the glossopharyngeal or vagus nerve neuralgia (it is extremely painful to swallow and it IS a cranial nerve). Because of the pain of these two nerves, and a lack of a good diagnoses (the trigeminal nerve problem was diagnosed but not the other nerve) she didn’t talk much at all and barely ate — because it was so painful. She ended up losing a lot of weight, and having a heart attack (the dr thinks it was because she wasn’t eating). After going to the hospital for the heart attack, a visiting neurologist was consulted, and this neurologist gave her the proper diagnosis, and she was prescribed two medications. She has to take the two medications, in higher doses to control the pain and be able to speak and eat. These medications (one of which is gabapentin) at the doses that control the pain, make her really tired, so that she only has a 1/2 day in her to do anything. This has effectively disabled her. I mentioned to her to read up on DMSO, and provided her with two of your articles (chronic pain and Injuries, and The FDA’s war against DMSO & America), and the only book I can find, DMSO Nature’s Healer. She said she was open to looking into using it after reading the articles & book and asked a nurse friend of hers about it. The nurse friend was (shockingly) excited and pro-DMSO, but, mentioned that since my friend has a heart stent, that DMSO and the heart stent do not mix, something about DMSO interfering with the stent (?). Does anyone know anything about this?
Amazing work! Thank you so much AMD. I've taken many good notes and will no doubt re-read this article many times. I've been experimenting - using DMSO on my knee along with MCT oil before walking makes the walk so much better. My hope is that the torn meniscus is somehow reforming. And if not, it feels like it is. Also starting to take internally and now... well now I have so many more things I want to try.
DMSO has been very helpful for me in dealing with several minor musculoskeletal issues over the past 8 months or so. It also seemed to have the effect of an increasing my overall general health…I seem to just simply feel better when I apply it. Feeling better to me has been even more valuable than the help with the musculoskeletal help even though they are probably one and the same. That being said, my wife and daughters complain about my odor. They say I smell like slightly sour milk. I have smelled this now and I agree that it is a bad smell. Any suggestions from anyone? Does this go away? Is it highlighting an underlying issue? Is there a way to mitigate it?
I would like to use this to help my husband who has both psoriatic arthritis (currently taking Cosentyx).Every joint in his body is hurting. In addition he has smoldering myeloma and anemia. I just don’t know how to use this to help him. I wish there were doctors around here that would help me learn to incorporate this into his care. I have a bottle on the shelf and have cut it with water 50/50 to rub on knees and feet. I never feel I know what I’m doing for sure. Any guidance appreciated.
Is DMSO safe for dogs? What wpuld be the recommended dilution for dental? My senior dog has had dental issues, gum disease, bad teeth. If safe I am considering diluting and try swabbing his gums.
I have been using topical DMSO for approximately 1yr now and tried the oral version this week. It seemed to do wonders for me by the 3rd day of taking it for my neck and back issues ( 2 tsp per day) but says I smell horrific. I have not had that issue with topical 70% DMSO and am wondering if there is any way to negate the odor I am emanating. My wife says I smell of creamed corn...lol...I can't smell it all on me. Any help would be appreciated because I had not felt as good as I did after a couple of days on DMSO in years.
Doctor, thank you for your wonderful help. Could an application of 70% plus 30% DMSO solution wiped over a 22 yr old friend's body beforehand be protective if he has a MRI (to ascertain if he has Multiple Sclerosis)? The 22 yr old has a sore back. There was a shadow on his back X-Ray and the doctor said he should have a MRI. Friends of mine became electrosensitive after MRIs with the dye, one friend does not recommend a MRI but the problem is the 22 year old wants a diagnosis (before going on a strict diet - the young sometimes hope to avoid such 'sacrifices'). I watched the documentary 'Living Proof' https://www.youtube.com/watch?v=Y56q_xkhSQg I wondered if a MRI without dye might still be able to show up CCSVI if it is there?
Thank you so much for these articles. Can you suggest a combination that you would recommend for Mast Cell Activation Syndrome in someone with MS , the MCAS observed as a consequence of to use a term “ The Elephant in the Room” that likely should not have been taken by someone with an Autoimmune Disorder. Currently the family member is using DMSO orally with Methylene blue and an improvement is observed with the brain fog aspect. But perhaps there is a better or different combination to avoid highly unpleasant and exhausting “ histamine dumps” as a consequence of any number of normal day to day activities including eating where it becomes a very bad idea to deny the body important food groups just to avoid these episodes. Any helpful suggestions gratefully received. Thank you for all your work.
I’ve heard you mention MSM as a byproduct of DMSO and some people are using it instead of DMSO. What is your experience with MSM and it’s effectiveness in these combinations? Is it possible to substitute MSM for DMSO in these remedies?My family cannot deal with the odour produced by DMSO so I am looking for alternatives.
What are your thoughts on women using DMSO topically on their face (with a carrier oil) if they have Botox or fillers?
Thank you so very much for all the hard work you’ve put into this series. Your efforts to get information about DMSO to the public is truly life-changing.
A few days before you published this article, I was trying to figure out how to manage pain from a strained hip muscle. Oral DMSO knocked it completely, but I don’t take it on work days due to the odor (my colleagues keep commenting that they “smell Onyx”). I tried hemp seed oil (purchased from Charles Warren Presents) with good relief, and 70% DMSO in aloe vera gel with better relief. I decided to try them together, and after 2 applications 12 hours apart, I had total pain relief. I applied the combination one more time after 12 hours for good measure, but have not needed it since. I didn’t notice hemp seed oil mentioned in your article so I thought I’d share my experience (though you do reference CBD).
Thank you again, from the bottom of my heart. I have made many lifestyle changes based on your articles and am feeling revitalized and rejuvenated at 60!
I have a question about how to use DMSO for my 17 year old son's acne. We have tried many things. Right now he is using a natural daily regimen which includes a rice flour scrub & topical herb based valves. I really want to help him. Where can I purchase DMSO? How should I administer to him? orally? Topically? What should I mix or dilute with? Thanks in advance for some instructions
my daughter has had good luck using CDS with DMSO. CDS first, when dry apply DMSO. she then does red light.
A lot of this is from ~AMD, other sources and some from friends and relatives….
Purchasing Topical Ivermectin Cream In 1 of 2 Ways:
1. Doctor Rx Prescription for 1% cream...pharmacy filled & purchased after doctor visit or diagnosis.
2. Over-the-counter private purchase of 1.87% cream at any veterinary, pet, or farm supply store for immediate use. Most creams & pastes sell for under $10 & are ready for immediate use without a doctor visit, copay, or pharmacy visit.
Purchase Ivermectin paste:
https://www.tractorsupply.com/tsc/product/durvet-ivermecti or farm fleet, fleet farm, etc…..
Acne: Ivermectin & DMSO
Dosage For Over The Counter Private Purchase:
Twice per day, massage in a pea-sized/pencil eraser-sized amount onto the affected area or lesion.
Then spray DMSO or use gel on. 2X daily.
Start with 25-50% DMSO for the face
https://www.ou.edu/research/electron/bmz5364/calc-percent.html
DMSO (dimethyl sulfoxide) is a simple naturally occurring chemical
Ivermectin/DMSO Application:
1. Spray on a combination of DMSO & spread ivermectin on first then spray on DMSO(doesn’t matter which one, I would start with Ivermectin ) If needed lightly rub in with 1-2 fingers to the area needed. If you don’t need to spread it to the area needed just let it air dry. Use 30-70% DMSO, use lower for the face per user response… usually 2 -3 puffs of DMSO is enough to spread on the face.
2. Spray on 1-3x times daily, if dryness cut back, or use Aloe Vera for moisture or redness. Just wipe off and/o by wipe off with water around the eyes or other spots if tingling plus don’t get in your eyes, keep your eyes shut when spraying. Can also just put (rub on)more Aloe Vera on for tingling.
Spray on the forehead and cheeks, or only the problem areas….
Always clean your face & hands with organic soap, use only one or 1 2 clean fingers (because of the DMSO) to lightly spread and rub into the skin) Let air dry, and wait for 15-20 minutes before applying makeup, etc….
Rinse finger(s) off with water and wipe with a towel after spreading DMSO to the area needed, to keep the smell of DMSO to a minimum.
It may take several months with stubborn acne to see moderate results…..
—————————
Other ACNE TXS
NOTE: Alternate various combinations best suited to your situation and what works best for you or the patient. Try different ones until you find one that works best.
* 10% topical Ozonated Glycerin(OG)
* Castor oil is supposed to be great for acne. Use castor oil and DMSO in the morning and try the below for the night if you have dry skin. Castor oil: https://www.stylecraze.com/articles/simple-steps-to-use-castor-oil-to-treat-acne/#gref
The problem with most beauty products is that they strip the oil out of your skin. Each time your skin is robbed of oil, it compensates for the lack of moisture by producing more oil which leads to oily and inflamed skin that triggers acne. Don’t be afraid of applying oil to your skin. The essential fatty acids that castor oil contains help in restoring the skin’s natural moisture balance. Apply castor oil gently on your face and massage in circular motions. You can even leave it overnight and wash it off in the morning.
* Ready to go premixed commercial CD: https://frontierpharm.com/collections/skin-care/products/chlorine-dioxide-acne-treatment-2oz lasts 18 months, great alternative to having to mix fresh every 5 days.
Apply first followed by DMSO. Remember CD is a very safe and effective antibiotic
* ozone cream… https://shop.puro3.com/puro3-ozonated-castor-oil/ or…https://shop.puro3.com/puro3-ozonated-olive-oil-2-or-4-oz often used alone although can be put on first followed with DMSO.
*Also can combine below product and DMSO, or just try alone, and/or can just use for minor-mild acne https://frontierpharm.com/collections/skin-care/products/chlorine-dioxide-acne-treatment-2oz
* 50% DMSO with Colloidal Silver is highly recommended for acne. Mix 40-50% DMSO with rose water or any floral distillate and Colloidal Silver in a clean glass jar. Apply using a natural cotton disk or ball to clean skin. For facial application, it’s best to use 50% DMSO or less till you see what you can tolerate. More is not better, start slow and increase.
* Hydrogen peroxide has also been used to enhance DMSO’s anti-aging properties. For the skin, it’s been reported to improve skin hydration and microcirculation when used topically, orally, or in a bath (where DMSO is applied to the skin beforehand rather than putting a lot into a bathtub). It also works quite well for acne (3% H₂O₂ followed by 30-50% DMSO sprayed on the affected area), blackheads, and pimples (apply 3% H₂O₂ followed by point applications of 70% DMSO).
Note: this combination is reported to clear acne much faster than conventional treatments, as it also addresses what is under the skin. An alternate regimen that has also worked quite well is 20-30% DMSO sprayed on, followed by CDS sprayed on, which is then allowed to dry (overnight causes a dramatic reduction in inflammatory papules and gradual clearing)~AMD
* Acne and Skin Lesions: A mix of 5% DMSO, 20% seawater, 3–5% urea, and aloe gel/almond oil (10:1) has addressed acne and neurodermitis. A gel with DMSO, lactic acid, urea, and seawater targets subsurface issues. Witch hazel is added for oily or acne-prone skin as a cleansing astringent. Note: For sensitive skin, limit DMSO to 10% and avoid synthetic hair products. Cleanse skin before application to prevent penetration of unwanted substances.~AMD
Hypochlorous acid is a completely non-irritating and incredibly potent antiseptic. It is naturally produced by white blood cells in the human body to help fight infections.
As such, I now use it instead of conventional antiseptics and for a variety of other things (e.g., when sprayed on the face with vitamin C, it’s often extremely helpful for acne). ~AMD
https://www.amazon.com/BRIOTECH-Topical-Skin-Spray-Hypochlorous/dp/B07T
Vitamin C: https://www.amazon.com/Liposomal-Vitamin-Absorption-Bioavailability-Antioxidant/dp/B09YCYKFWX/
HOCl attacks invading pathogens, breaking down the cell walls before destroying unhealthy invaders. The antimicrobial acid is lethally effective in carrying out its protective mission. (Think of it as your own internal Batman.)
“It’s your body’s natural response to bacteria, and it is very effective at its job,” says Dr. Khetarpal.
* Fight bacteria that causes clogged pores and acne
* Speed up wound healing and repair damage
* Combat inflammation and conditions such as eczema or psoriasis
The best part, though? HOCl is nontoxic and handles this hard work while being incredibly mild on your skin. That gentleness is a byproduct of it being naturally produced by your body’s immune system.
“It’s great for sensitive skin,” notes Dr. Khetarpal. “It’s not going to give you the dryness, burning or irritation of other products [such as alcohol].”
——————————-
Possible Acne Treatments
Ozonated Glycerin
Hypochlorous acid and 10% OG solution: may also be combined and should work for acne
Another possible acne treatment
DMSO & OG: (Ozonated Glycerin)
Dr. Larua says can use 10%OG & DMSO for topical application https://drlauraenfield.com/dr-enfields-video-lecture-on-ozonated-glycerin/ (last question at end of video.)
The benefits of Ozonated Glycerin are wide-ranging and impressive.
It has been shown to improve a variety of skin conditions including acne, eczema, psoriasis, age spots, irritated skin, herpes and shingles outbreaks, fungal infections, and even certain types of skin cancers.
As an antimicrobial, it offers powerful support for difficult-to-treat infections such as candida, Lyme disease, mycobacterium, and other resistant bacteria and protozoa.
In addition to fighting infections, it promotes wound healing, moisturizes and hydrates the skin, improves tone and elasticity, and supports overall detoxification.
Remarkably, it crosses the blood-brain barrier, making it a promising option for reducing neurological inflammation as well as systemic inflammation throughout the body.
It can even restore a sense of smell lost due to infection or injury, helping patients regain an important part of their quality of life.
Purchase online:
* PURO3…. Pure03 has OG available at wholesale prices for providers.
* OG is available from PURO3.com with discount code REDWOOD. I am told that PURO3 will be making their OG from our preferred glycerin source - organic USP glycerin derived from coconut oil. (I just completed a 1000 ml batch for office use. ORP is over 600 (excellent) and the peroxide test strip shows 5000 ppm, excellent according to Dr. Shiota’s teachings).~Rowen MD
* DRROWEN for SimplyO3. https://www.simplyo3.com/products/glyzine-ozonized-glycerin-ozonated-glycerin. You can get a discount with Simply O3 using this site: https://lddy.no/1fidt or at their regular site using the code.
Keep small amount of the mixtures refrigerated. 90-day 1/2 life is 90 days
Keep the bulk of unmixed OG in freezer as this will last 2 yrs.
Excellent! I have extremely severe Eczema on my face (that tracks perfectly with all my sinus passageways). My face looks like it was fried! Because of your writing, I started using 99.9% DMSO made into a cream for 70/30. IT IS THE ONLY THING THAT WIPES OUT THE ECZEMA! It has also taken care of an ankle/foot injury that was horrible (they are like new). I am just not sure when to cycle on and off. Keep up the great work!
researching using DMSO to treat forearm tendon pain that i believe is being caused by Seronegative Enthesitis. I want to try it with magnesium chloride or castor oil. I am hoping for some direction on finding a topical mag chloride product i can combine with DMSO.
I take 1.5T DMSO in a lime juice/water solution 4x/day. I have MS and am attempting to heal damage. It has been incredibly helpful for pain and energy. In May and June, separated by 2+ weeks I took 0.2mg/kg of IVM as part of an antiparasite protocol. In June and to a greater extent July my vision became a lot worse. Near vision contacts had been at -6.0 and went to -8.5. A full panel for thyroid, DM, and electrolytes were all normal so I was baffled but then read this article tonight. Could this have been due to this DMSO/IVM combination?
I also had another spot of melanoma come up on my leg (previous Mohs procedure on same legs 11/18 stage 1a) that I treated with chlorine dioxide and it seemed to improve until I had some skin breakdown. I stopped. It has healed. If it needs treatment again I’m going to use your advice and treat with DMSO and IVM topically.
Thank you so much for your work. I’ve been a reader since the first small pox article.
Blessings
Does DMSO enhance absorption of any lotion on the body or just at/near the application site?
Great research! Thank you.
My MRI shows I have fluid in my hip joint and a torn labrum. My sports med doc wants to give me 2 PRP shots. First she wants to calm it down with a cortisone shot then do the PRP a month later. She said I can go straight to the PRP, but it could be extremely painful after for a week or two since it has not calmed down. I also have L5-S1 severe disc narrowing.(Aside: Patient derived stem cells are not legal in the US and I don't want to use umbilical cord ones.) DMSO Advice? MRI DX:
There is a small effusion with mod-severe osteoarthritic changes and grade 3-4 chondrosis. A non-displaced tear is present in the anterior superior labrum from 2:00-3:00. Mid bilateral common hamstrings tendinosis is present. There is mixed fatty atrophy and intramuscular edema in the adjacent quad fem muscles and can be seen with ischiofemoral impingement. Severe disc space narrowing and disc desiccation L5-S1.Deep acetabulum..can predispose to pincer type femoral acetabulum impingement. Also, how long should I stop doing DMSO before I get any shots?
My question — for which I’m yet to find the answer anywhere — is to do with the quantity of DMSO application and frequency, both with the drops and the gel, and is that different with various ailments.
Can anyone answer that with authority?
Perhaps The Midwestern Doctor can give us an idea, or point to a post to enlighten me.
New subscriber here. Love your content!!
Does oral dosing with DMSO reduce arterial plaque? I am unable to find a local physician who will administer it IV. I am 72 with familial hyperlipidemia and very high lipoprotein A levels. A carotid ultrasound revealed the presence of minimal arterial plaque. My cholesterol is 350 without drugs. Ezetimibe reduced it to 230. I have declined statins and Repatha as both are toxic and have serious adverse effects. I'm stumped on how to treat my familial hyperlipidemia, high lipoprotein A and carotid arterial plaque. My mother and maternal grandmother both had familial hyperlipidemia and died of strokes at age 90. Does oral DMSO decrease the arterial plaque, or at least mitigate further accumulation? If so, how should I dose it?
Does oral dosing with DMSO reduce arterial plaque? I am unable to find a local physician who will administer it IV. I am 72 with familial hyperlipidemia and very high lipoprotein A levels. A carotid ultrasound revealed the presence of minimal arterial plaque. My cholesterol is 350 without drugs. Ezetimibe reduced it to 230. I have declined statins and Repatha as both are toxic and have serious adverse effects. I'm stumped on how to treat my carotid arterial plaque. My mother and maternal grandmother both had familial hyperlipidemia and died of strokes at age 90. Does oral DMSO decrease the arterial plaque, or at least mitigate further accumulation? If so, how should I dose it?
Cyclodextrin
Cyclodextrin pulls cholesterol (cell membrane, lipid droplet, crystalline, and oxycholesterol) out of the vessel wall, in a process that elaborates nitric oxide (vasodilatory and atheroprotective) and decreases release of inflammatory cytokines. Your symptoms begin to attenuate in 2-4 weeks (biochemical effects). With longer use, anatomic plaque regression can occur (as evidenced below). This molecule will save millions of lives, decrease our need for vascular procedures, and save billions of health care dollars.
Within our paradigm, that of Integrative Cardiology, the focus is risk factor reduction, not to directly reverse anatomic atherosclerosis, but rather to prevent plaque progression or plaque activation – and thus protect you from clinical events (heart attack, angina, and heart failure). Cyclodextrin will dissolve crystalline cholesterol as well as intracellular lipid droplet cholesterol.
* https://atherocare.com/products/atherocare?variant=46347681890559
* https://www.cavadex.com/science.html
* https://heartfixer.com
* Cyclodextrin.htm#Physician%20DePlaque%20Thyself!
* https://heartfixer.com
* Cyclodextrin.htm#Coronary%20Artery%20Decalcification
Treatment
Dr. James Roberts. Board-certified and university-trained in internal medicine and invasive cardiology, a Fellow of the American College of Cardiology, and has completed coursework and passed written exams in chelation therapy, oxidative medicine, bariatric medicine, and anti-aging and regenerative medicine, where he is considered an advanced fellow. Teaches the principles of integrative cardiology to physicians within integrative medicine training courses and have been involved in research on new drugs, devices, and nutraceuticals.
Right now, given the safety, low cost, and obvious efficacy of CD, my recommendation is:
1. In the setting of symptomatic atherosclerosis, 2-3 months of CD makes sense (or until symptoms resolve) followed by a maintenance program of 1-2 doses per week, with repeat 30-day programs once or twice a year.
2. In asymptomatic patients with moderate plaque (particularly if risk factor control is difficult) one month of CD twice a year can be used to make up for imperfections in our preventive program.
Keeping in mind that CD does not remove the underlying causes of atherosclerosis, ongoing risk factor reduction remains important, but with the benefits of CD, we may be able to cut back on the drugs which are most problematic to you. https://heartfixer.com/Cyclodextrin.htm#Coronary%20Artery%20Decalcification
Note: We can use change in carotid plaque and intima-media thickness (discussed elsewhere on this site) and coronary artery calcium score, as means of quantifying CD efficacy.
Very interesting...thank you. Would you recommend treatment with cyclodextrin for asymptomatic patients with familial hyperlipidemia and elevated lipoprotein A? Recent calcium score was 0 but ultrasound revealed the presence of carotid arterial plaque, albeit it minimal. The write-up you kindly provided focuses on cardiac events rather than cerebrovascular pathology causing stroke risk due to carotid arterial blockage which is the long-term concern.
MWD- I am very thankful for all your work, but in particular for this article, I am extremely interested in the Hydroxymethylfurfural (5-HMF) for CFS. One of my doctors thinks it's ME-CFS d/t the post exertional malaise and a few other symptoms. Anyways I'm desparate for some normalcy. I have already started mixing an oral solution of DMSO with honey it's supposed to have 5-HMF in it--but is it enough? Does this take a long time to take affect? I am already on selenium, boron, and magnesium, as well as other mitochondrial boosting supplements. I see the German supplement you have referenced, is this better?
Thanks in advance. I am always amazed at how you can put so many pieces of information into an article and tie them all together. Bless you.
Are there any practitioners that could help using DMSO in complex medication situation?
Are there any practitioners that can help with using DMSO in complex medical situation?
I'm interested in any input regarding where/brands of DMSO people are purchasing.
I've been using DMSO store pharmaceutical grade 99.995% but I have found myself wondering about 99% veterinary grade from reputable sources. The obvious question is what is contained in in the .995% difference. An AI analysis indicates water is likely the most frequent impurity often comprising as mush a 1% of non DMSO content. Other possibilities Dimethyl Sulfide, Dimethyl Sulfone, Mercaptans, heavy metals, residual solvents or organic impurities (including acetone, ketones, acids, bases, halogen compounds-rare). If anyone has any educated input or experience using other then pharmaceutical grade I would appreciate the input.
I would also appreciate any input on healing shoulder injuries such as tears, impingement and bursitis. I’ve been researching formulations and have been using DMSO with magnesium and Castor Oil.
I was also wondering about creating mixtures using peptides such as BPC-157 (1419.54 g/mol) or GHK-Cu (~403 g/mol). Generally, molecular <500 g/mol is considered ideal for penetration but I’ve read anecdotal reports supporting trans-dermal delivery with DMSO for larger molecules. Does anyone have experience with using peptides with DMSO topically for healing these types of injuries?
https://jacoblab.com family of Stanley Jacob
Thanks for the suggestion I appreciate the resource.
Ive been using DMSO on my daughter for hidradenitis. I believe it has helped but maybe combo with something would help further. Does anyone have further suggestions on how to use for chronic skin condition HS. They are like boils that form tunnels under skin. She recently started drinking it but college starts and not sure she will be able to continue due to smell. Any suggestions would greatly be appreciated.
I searched on X and found this article:https://x.com/vigilantfox/status/1953126737497256099?s=46
Prayers!
thank you very much
Over a year ago I had an infection in my collar bone. I applied Arnica, Comfrey compresses, and castor oil with little success. Then I applied DMSO, 92% plus 8% Aloe Vera, and within hours and a few days, I noticed the swelling going down, the pain subsiding and joint movement in my shoulder vastly improving. Within 6-8 weeks, between applying the DMSO and organic Castor oil at least 3-4 times daily, I was self healed. It was a truly amazing experience. This all began with me following you, my most favourite midwestern doctor, to realize the magic that is DMSO. My husband had a small but inflamed and painful lump in his left breast. The doctors wanted him to have a mammogram. Utterly ridiculous! Instead he started applying DMSO with Castor oil and yes, within 6-8 weeks of daily topical treatment, the lump diminished, the pain was gone and even without applying the treatment, it continues to shrink. I had 2 separate friends develop lumps below their earlobes. Infections it seemed. I bought them DMSO and castor oil and you guessed it. The lumps disappeared. My appreciation for your wealth of information, freely shared your research with us is beyond words. You have made our lives all the better because of your selfless efforts to make us aware of how we can heal ourselves. thank you.
Thank you! That's a big part of why I try to focus on specific areas and go deep enough into them to provide information that will really help people rather than superficially covering a lot of topics that get easy traffic.
Hello everyone,
I need some help here. My mother is taking corticosteroids for her autoimmunity disease (doctor diagnosed her condition as atypical lupus) and she's going to change the therapy now to Myfenax (mycophene motefil) But all these therapies have very bad side effects and already had a negative impact on her body.
Can you help me find an alternative cure? Reading AMD, I found that DMSO could help by diminishing side effects. But where can I find it here in Europe? What is the dose and how to apply it in her situation? I don't have any idea and we don't have here any doctor that knows about this kind of stuff.
Any info /advice you could provide of any kind, I would be enormously grateful to you🙏
Hello everyone,
I need some help here. My mother is taking corticosteroids for her immunity disease (doctor diagnosed her condition as atypical lupus) and she's going to change the therapy now to Myfenax (mycophene motefil) But all these therapies have very bad side effects and already had a negative impact on her body.
Can you help me find an alternative cure? Reading AMD, I found that DMSO could help by diminishing side effects. But where can I find it here in Europe? What is the dose and how to apply it in her situation? I don't have any idea and we don't have here any doctor that knows about this kind of stuff.
Any info /advice you could provide of any kind, I would be enormously grateful to you🙏
Thank you very much
Has anyone had any luck with parkinsonian, corticobasal syndrome or other parkinson ++ diseases ?
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety/comment/72436114
Thanks!
Doctor, what is the best brand of DMSO I can buy for a family member with liver cirrhosis? Where can I obtain it? I think DMSO is his only hope. Thanks so much.
https://www.midwesterndoctor.com/p/how-dmso-protects-and-heals-the-internal
I've used it with various natural products hoping for amazing results in hundreds of people and I must say it's a bit of a nothing burger. It seems to be excellent in acute C-fiber injury though. In muscle spasms, arthritis, nerve impingements and ligamentous/cartilage pain, acute or chronic pain, nothing's happened. Hundreds of individual cases.Only topical to be sure, but I can't risk internal applications and the articles suggest topical has a lot of utility. My attention is turning towards assessing effects on long-term outcomes for reinjury
Hi MWD,
I've been dealing with what was diagnosed as severe allergic contact dermatitis for maybe seven weeks now. The dermatologist thinks it’s a poison ivy type exposure. (I’m not entirely sure if the diagnosis is correct though top AI models agree with her.) I’m on my second course of oral prednisone.
(I’m trying an new approach to cleaning my skin today since I suspect I still have oil residue on/under my skin and when I weep fluid, I’m spreading the oil and rash.)
1) I’m concerned that using DMSO will potentially bring the urushiol oil deeper into the body. Amandha Vollmer warns against using it in this case in her book. Any thoughts on that?
2) Any concerns with using DMSO at the same time as oral prednisone?
3) Given I have a systemic inflammation going on, maybe applying DMSO to carry anti-inflammatory substances to body in an non-affected area?
4) Any suggestions you have in general with or without DMSO will be deeply appreciated. It’s been very difficult.
Thanks
1) I've had two people who had a very good response for poison ivy:
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety/comment/72409302
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety/comment/135933078
However I've not personally used it for that.
2) It will increase the potency so a lower dose can be used. This typically comes up in longterm usage rather than short term.
In my own experience, washing urushiol off, repeatedly, and laundering well any clothes that have come in contact with the oil is crucial.
Could you please point us at a "how to" protocol page for both topical application and ingestion (eg drinking a dilute solution). For general ailments. I've lost track and need guidance.
That is in this article under this section:
DMSO dosing
Thank you, I had not had time to go through it all.
It would be useful to have a standalone "how to" guide as well. You are so prolific that it can be hard to track and remember.
The good doc promised to do it after the series is done. :-)
One portion of this remarkably comprehensive piece was of particular interest to me: "Note: DMSO will leach many plastics at concentrations above 20%. For this reason, 15% or lower is often advised for situations where it has to come into direct contact with them. Conversely, when DMSO is mixed with water, it will temporarily heat up. This is a natural dissolution reaction between the two which has nothing to do with anything being leached." I have been wanting to nebulize DMSO for some time, but have held back due to concerns about contact with plastics. There are several plastics which are apparently safe to use, but no manufacturer of nebulizer supplies has responded to my inquiries about their products. I would likely be using only a few drops of DMSO in, say, 10-15 ml of saline. Based on the quote above, am I correct in assuming it would be safe no matter what the type of plastic cup? (I would dedicate one cup purely for this treatment, so there would be no concerns about contamination from other medications.)
Most likely
My Golden Retriever has a Mast Cell Tumor at the base if her tail near her body. I have been applying a 70% solution 3X day externally to the tail and giving her the Tucker IV solution, (Hematoxylin /DMSO) orally, 5 ml, 6X throughout a day. Could I give her an injection of the Tucker solution at the tumor site? In addition 2mg of prednisone is given to keep the swelling down.
Elle is otherwise healthy and getting quality food and essential vitamins and iodine.
The Vets want to remove her tail, not a option for me.
Any guidance would be appreciated, I know you are super busy. Vern Boltz
My Golden Retriever has a mast cell tumor at the base of her tail. I have been applying 70% DMSO
externally #X a day, and been giving her the Tucker IV Hematoxylin dose orally, 5 ml orally for about 6X a day. Could I give her an injection of this solution at the tumor site. The Vets want to amputate her tail and the tumor is very close to her body. I know you are very busy, but if you have any ideas, it would be very much appreciated. I am giving all the proper High Quality Vitamins and Iodine as well. Thanks, Vern Boltz
Dr. Grindle found injecting it into human tumors didn't work, but there is otherwise very little data in this area. However injecting into the victinity might.
Rose Bengal seems to do better with direct injections, but I'm not aware of it being tried in that tumor type.
Wish I could tell you more.
Thank You! any thought on quantity and frequency.
All the known doses are in the DMSO hematoxylin article.
Try OG per https://drrowen.substack.com/arthey inject around the tumor
Both my husband and I (age 63) have a variety of ailments that the doctor says might benefit from DMSO. Intuitively, it seems the oral route would be most advantageous, but doc suggests topical first. Will we get the same benefit from the topical?
Oral is more systemic but good to start with topical to see how it affects you.
Have you considered writing a book on this subject? Thank you for this fantastic post!
Yes, but I keep on updating and revising these articles as I learn more, and I don't want to be locked into information I no longer fully agree with (or feel is incomplete) which will happen if a book is written.
How does the German DMSO group work? Do they have an online forum, or a web site, or meet-ups, or?
A lot of it are meetups and courses in Germany. However there are also a lot of groups on facebook (which you can find by searching DMSO and selecting groups)
Hi MWD,
Thanks for another great article that would take me months to digest and implement. I have some follow up questions.
1. The hypothesis of physiological differences of L-and D-lactic acid and using them to treat is cool.
Most suppliers seem to only have DL-lactic acid mixture. Is there D-lactic acid only product that you would recommend?
2. In your opinion, how should someone balance taking oxidative treatment and taking antioxidants on a daily basis?
Thank you!
I'm writing this short note to let you know how much I value you and your wonderful dedication to sharing all the information you have discovered over the years. I'm currently reading and saving
"The DMSO mixtures transform natural medicine", "How DMSO cures eye, ear, nose,throat and dental disease", and "Exploring how skin health goes hand in hand with whole body health."
I am a retired naturopathic and chiropractic doctor of many years and I'm learning so much from you.
Thank You, thank you very much,
Dr. Kathy Acquistapace
Please let me know if you find a solution. I think these articles are wonderful but they cover so many issues it is hard to find what you need. I am on a PC
every browser has the option to search documents and webpages for terms, it's normally control f or command f
Thank you. I will try to find neuropathy
Does anyone know of a source of quality hematoxylin in USA that is pure enough to instill directly into bladder or rectum with DMSO to treat prostate cancer?
I would love to have your DMSO articles in book form so I could give copies to friends and family.
The problem is that since I keep on updating and revising the articles, I don't want to put a book into print I later disagree with parts of.
Makes sense, and I appreciate the diligence. Off to gift a few paid subscriptions!
Doctor,
If you have not done so already, will you please compile this full series into a book? I am medically complex, poly-pharmacy and have so many uses for DMSO that I really need the information in one place. I am more than happy to pay for it in any form, including an indexed PDF.
Thank you,
Emily
hEDS, ankylosing spondylitis, Sjogrens, Raynaud’s, MCAS, dysautonomia, asthma, hypothyroidism, fatty liver, metabolic syndrome, PCOS, rosacea, high blood pressure, low kidney function, vestibular migraine with aura, macular degeneration, etc, etc. My list of specialists looks like the hospital directory. 22 Rx, ~25-30 supplements including vitamins, minerals, peptides, homeopathy, DMSO, herbs. I am forever running multi-variate, n=1 supervised experiments on myself. Had I known my BS in pre-med bio and chemistry was going to figure so heavily into my personal life, I’d have tried harder in organic chemistry. I’m a city planner by trade.
Is there any chance that you can share doctors info, who are using this in their practices. It is impossible to find them otherwise. And to share the “communities” where we can join others and learn more and give support. Until the US allows us to have this information, we have you, for which I am eternally grateful, but we need more. Thank you for your diligence and desire to help us without pharmaceutical drugs and surgery being the only remedy.
A lot aren't in english (and hence difficult to go through) but there are some currently active ones on facebook (you can find by searching groups for DMSO).
Did not see anything under DMSO on Facebook
There are at least 3 DMSO groups on facebook
I found them, TY. Can you tell me why the dr recommends taking oral DMSO after a meal and slowly?
i just started taking about 1 tsp DMSO (99%) with water on an empty stomach. I chase it with more water. Did 1/day, then 2/times day, with no issues..
The first time I tried to add it to my morning coffee with heavy cream. the results were an "explosion".. Lesson learned.
I wish I could provide some explanation but I don’t know. I have read to take it before a meal. So I am confused about the appropriate timing. If I come across any new information in the book I am reading, I’ll let you know.
TY
I found one. Can you give me names, please? TY
DMSO for Non-Academics, DMSO and MSM, DMSO AND DMSO2 (MSM)
TY, I finally found them.
All the reading I have done from MWD and others about DMSO, I have not found good information about oral ingestion causing any problems for someone with hip implants. If it is OK. I need some dosing advice. I have a lot of surgical scaring, but I'm most interested in one area in particular. On the scar there is a nodule of scar tissue. Can it be released by DMSO? I'm interested in oral for detoxification of metals and other environmental contaminants. MWD mentions taking with Chlorella or Cilantro.
Would you say dmso is safe in pregnancy as well?
You speak of the DMSO community, but I can’t find a community anywhere online. I was hoping for message boards or some-type of online forum for expert & newbie DMSO users to collaborate. For instance, I’m trying to recreate a DMSO-frankincense-hemp cream that is no longer available, but I’m having a hard time getting the texture correct. So I’d love to talk to people with more experiencing making DMSO creams about the issues I’m having. I also have somewhat random questions like can I use a silicone spatula to transfer my DMSO cream(s) from one jar to the next.
The issue is that most of it isn't in English or is on older forums people don't use as much now. There are also a lot of English groups on Facebook but they aren't as detailed.
That’s what I was afraid of. Thanks for letting me know though.
Please add an index or some local search capability on your DMSO and really all of your articles. I am focused on Parkinson's and want to read every story you have on Parkinson's and DMSO. This search would apply to any condition and helpful to all.
That will be done once the series is over. If not, I would have to spend a long time redoing it each time an article is written.
I used to own a medical publishing company, and indexing was a major task in the production of scientific material. There are indexing programs that publishers use to list all “important” words, along with all page numbers that contain those words. It’s not perfect (indexes some common words; misses some unique words), but it’s better than trying to compile them by hand. (Not to mention automatically updating all the page references if pages shift with edits.)
In the meantime, Tom can print each article to a PDF, then use the Acrobat reader’s “Find in document” search function.
Wasn't thinking of a manual index, rather a search function for all articles with keywords. Google search with site: qualifier would work but might miss parts behind paywall. I will play with that for now. Don't want you spending time to write a manual index, you got more important things to do.
Also follow @makismd on X who posted that fendbendazole cured/helped parkinson’s
Thanks Doc; great review and details. . . not done yet but got to point# 10 and was confused; it sounds contradictory. . .
"With both topical and oral DMSO, people generally find that as time goes on, their tolerance to it improves. Conversely, if it’s used too frequently, a tolerance can develop, so it’s generally advised not to take it 1-2 days a week."
Please explain . . . "NOT to take it 1 -2 days a week", thx
Good catch. I was defining tolerance differently in each case. Let me clarify that.
Anyone know providers using DSMO in the Charleston SC area? Thanks
I bought a bottle and two larger jars of the gel. I feel inflamed all over and I feel like my blood is sludgy. I have difficulty breathing basically I feel like my blood is not getting oxygenated. Can I use the gel like I would a moisturizer all over my body?
Yes but start with smaller areas and make sure you tolerate the gel's concentration.
Thanks, Doc!
I'm interested in trying the galactose DMSO combination for my husband with Alzheimers which we are seeing both a Functional Medicine DO and a Naturopathic doctor for but neither is knowledgable about DMSO. My husband also has metastatic prostate cancer which he was being treated by a Urologist that gave him so much Lupron that it depleted his testosterone.I I I I I think that was the start of his AD. Can someone tell me where to purchase galactose and which brand is best.
This article was so full of information I decided to print it so I can study the parts I need. I'm doing IV chelation therapy and a bit confused how to use the DMSO with it. I was putting DMSO on my arm for something else when I went for chelation therapy and I kept blowing veins during treatment.I quit the DMSO in fear that it may of caused it. Hopefully rereading everything on it will help.
Wish I could find a medical practitioner knowledgeable in DMSO, especially for my husband.
I'm essentially trying to create that DMSO doctor network in the USA. Currently the people I know who started using it from these articles all told me:
•It performed miracles.
•Their practices filled.
•They've moved away from their old jobs/pratices they worked with to do DMSO full time.
•They can't currently be publicized here because they are already full of patients.
As time moves on, my hope is that their successes and patient experiences will make others want to become DMSO doctors to and have there be a greater supply of practitioners in the USA (whereas in Europe and Germany there are a lot more).
Galactose isn't hard to make so it should be easy enough to find a clean brand.
Thank you for your reply. Fighting both metastatic prostate cancer and Alzheimer’s is tough. He does UBI, organic diet, supplements and a lot of exercise and rubs DMSO on his neck and head. I keep thinking maybe we’re missing something And little support from family and friends because of most don’t want to admit our medical system has failed us. It’s genetics is what I’m told. You are a God send. Reading You gives me strength to keep fighting even when I feel alone.
Stop statins and don’t eat sugar/carbs.
East grass fed beef and organic pasture raised eggs and use butter and stay away from seed oils
We do all that in addition to organic fruits and vegetables, drinking reverse osmosis water and eliminating aluminum sources. We eat grass fed beef raised on a regenerative farm.
Doc, it would not be so hard to start a forum for people who are experimenting with DMSO. There, both patients and doctors could share, anonymously if wanted. Forums make discussion of subtopics much more user-friendly than substack. There are a number of plafforms that are pretty easy to set up, like for example https://www.simplemachines.org/ (the granddaddy of them all, I think).
Many are free and open source. Also customizable.
https://x.com/makismd/status/1952097176110444628?s=46
Question about using for connective tissue disorder and lymphedema: is D-lactic acid the same as lactic acid? Where is the best source to purchase that plus mag lactate? Am I looking for a powder or a liquid solution? Thank you!
no. L-lactic acid is the more commonly sold form.
Recommendations for medical professionals in the Charleston, South Carolina area that use DSMO treatments. Thank you.
AMD I have had neuropathic pain caused by a surgery 25 ago. Several months ago I started using DMSO 70% gel over the scars as well as all areas affected by the pain. The reduction in pain has been remarkable. I am playing with the idea of also using DMSO orally to see if I can get further relief. I would not have tried DMSO if not for your work Thank you!
Question. Can DMSO reduce calcification in an Aortic valve? If so how would it be administered Thanks
Maybe but we normally just use IV EDTA for that.
AMD what is the MOA of EDTA treatment. Does the calcification dissolve so completely that there is no risk to blood vessels—occlusion? Thanks!
Thanks for the reply.
It really only requires changing the order of paragraphs for each of your comments.
Can DMSO be used in any way for neuropathy following nerve damage?
Yes that is a very common use.
What you are specifically asking for will be done once this series is completed.
It would be ever so helpful if you could list the DSMO information with the complaint/issue/problem at the top of the para then followed by the DSMO + whatever after that.
Readers could then go straight to the illness/problem that affects them rather than having to read everything to find a paragraph that is relevant to them. I have bought DSMO cream and liquid but I'm still not sure how to use or what to use for other than a direct application of cream for pain.
Thank you so much for all your research.
I did not do that because it would make the articles much much longer and harder to follow the key points to understand the subject in general (and more repetitive). I put the caveat about that in the article so they could just search for what they want to find. Conversely, if I say condition:do x y and z, people will do x y and z without the context to understand how to do it safely or correctly.
I wonder if some format like that used by earthclinic.com?
Having read all the articles with repetitive information makes it helpful to remember the haves and have nots. Also I would recommend buying The DMSO Handbook by the German author Fischer.
Eral - I kept thinking the same thing as I read through this amazing article. Or maybe put the complaint/issue/problem in bold font . . . Now I'm wondering if there is a way to do a search through a substack article. I'll have to go back in and check!
Control/command F.
Is this for a Mac? Thank you!
I'm on a PC
You mention using a solution in a spray bottle. But is there such a thing as a spray bottle that isn't plastic and can handle DMSO?
Natural Metabolites —You mention many have had success treating CFS while others have been used to rebuild connective tissues. Can you say which ones for each? Or do we get Fischer's book?
I do not believe you read the whole article. I wrote a long section on how 5-HMF is used for that.
There are a few DMSO resistant spray bottles on the market but we are not sure which the best one is which is why I have not endorsed a specific one.
Thanks for pointing that out! Apparently when my brain hit Hydroxymethylfurfural it sort of skipped over that, having never heard of it!
DMSOstore.com sells spray bottles. They’re expensive, but they’re made of heavy glass and have a high-quality sprayer that sprays an even mist, unlike the ones at the dollar store that sputter and spurt.
Thanks. I see the tube is still plastic though. I never know when I'm being over paranoid about toxicity being transferred through DMSO.
Thank you for all your extraordinary work.
Combining DMSO with other substances usually strengthens their effect, as you describe.
My question is whether this applies generally only for the benefits of the other substance or also for its potential side effects?
Under the first hypothesis, the DMSO wpuld potentially allow to get similar results with a lesser quantity of the other substance, which would essentially be an economic advantage (depending on the cost of the other substance).
Under the second hypothesis, you could potentially have a major clinical benefit as you would be able to get the effect of a much greater quantity of the other substance without its potential side effects.
That's basically why DMSO works so well with chemo.
With pharmaceutical drugs you can run into issues with them potentiating an inherently toxic drug, in which case lower doses are needed.
I thought this would be an issue with natural substances, but most of the issues were either peroxide being too concentrated or the agent being too acidic.
Thank you whoeheartedly for your answer!
I did not fully understand the second part where you wrote;
"I thought this would be an issue with natural substances, but most of the issues were either peroxide being too concentrated or the agent being too acidic".
Is it referring to drugs or narural substances? What does that mean and how can this be mitigated? I am asking this from my perspective as an (educated) layman.
It's explained in the article, but essentially there have been very few issues with natural combinations, and the only ones were either:
the thing mixed with DMSO was too acidic for tissue in the vicinity tolerate
or hydrogen peroxide mixed with DMSO was too concentrated for tissue in the vicinity to tolerate.
Thank you very much. Sorry for asking about something that is excplicited in the article, I will go in-depth over all the precious information you so kindly share with the world!
Thankyou for this compendium of DMSO. It is a book in itself (I am printing off a copy for quick reference).
Do any DMSO combinations help to dissolve blood clots? I see DMSO helps with strokes and heart attacks but will it help to dissolve existing blood clots in deep vein thrombosis, brain capillaries, etc?
DMSO alone does and I know people who've done that, but a lot of other things with anitclotting activity have also been mixed with DMSO, some of which I detailed here. The main thing I am not sure is if it can work with nattokinase/lumbrokinase/serrapeptidase because they in theory are too large for DMSO to transport, but people have had success with heparin (which also should be too large to transport).
I listen to a lot of different shows on rumble. Wouldn't it be GREAT if MWD had a show!!! Meanwhile, the powers to be would surely take down rumble or prevent the show from airing. And maybe his/her info wouldn't be appropriate for just everyone to hear.
Decent quality shows take an insane amount of time to produce. I'm beyond my max (even with outside help) just doing this substack.
Please no. :-) See my comment above.
I totally understand! The info you put together and share I would say surmounts way beyond the sermon on the mount! Amazing Gems! Always ahead the game & right on target! And they provide incredible opening for many to roll forward in many wonderful exponential ways! Infinite Appreciation AMD!!!
Gadz no! I don't do podcasts, and vids only rarely, mostly for DIY kind of stuff. Takes forever to listen or watch compared to reading. Just bloody annoying... :-)
Also, I may have asked this question before, is it ok for those on SRI's to take dmso internally?
I have not heard of this being an issue. I found one study where patients were on antidepressants and DMSO increased the likelyhood of the treatment resistant depression being cured without any side effects. However, it used TCAs rather than SSRIs.
Yes, that makes sense! DMSO is miraculous!
SSRIs? Certainly not close to each other. I'd space them far apart and start at a very, very low dose and gradually work up. SSRI toxicity is not a safe playground. There are some points in the above article to reference, regarding the conditions SSRIs treat. As a side not, I work really hard to get patients off those meds. It can be tough, but I promise its worth the effort.
Thank you for your reply Danbob. Yes, I agree, I'm thinking there shouldn't even be any SSRI's. A friend of mine has been on them for a long time, I forget which ones. Medicinal mushrooms seems to be helping some people get off of them. Spacing out dosage time makes sense. And milk thistle, dandelion, etc for helping with the toxicity.
Very low dose, sublingual, at home ketamine as well. Very promising. I see it similar to microdosing of psilocybin.
85% of neurotransmitters come from gut microbiome. Need a good probiotic such as Gundry’s Bio3complete, B Complex, Magnesium and stop sugars, eat grass fed beef and butter, organic pasture raised eggs…
WOW! Amazing & Excellent!!!! Your work is Incredibly Exciting!
Question, what can you say about cervical myelomalatia?
Can it be resolved -cured? Could the spinal cord be restored? At the very least, I'm thinking dmso might be one of the best way to deal with the pain, topically and internally, and maybe with the addition of? Wild lettuce, or? A woman friend of mine has been seriously suffering from this condition.
I think it has a good chance to helping given the nature of the condition, but I am not aware of it having ever been tried. Since there are so many conditions DMSO could be tried on, most haven't been tested.
That said, I have read of things similar to cervical myelomalatia that did respond, and might have met the criteria for that diagnosis but never were diagnosed as such.
You're right! If anything, it could be the best possible ticket! Now I need to somehow convince my non believing friend to try it! I think both topically and internally.
https://open.substack.com/pub/amidwesterndoctor/p/dmso-is-a-miraculous-therapy-for?utm_source=share&utm_medium=android&r=dumok
Thank you! yes, I was just looking at that article the other day, scanning quickly. And MWD's article about the brain & spinal conditions. I didn't see anything addressing this condition in either articles.. I might've missed it. Maybe in the MANY comments, haven't had time to look at them. The core of this condition is the spill cord is softening, degenerating. I'm wondering if DMSO can restore the spinal cord. It makes sense that dmso with other agents could be very beneficial for addressing the pain. My friend can only stand/walk an hr or so a day (groceries' tc), otherwise she has to be on her back.
I wouldn't hesitate on this at all. Seems like the perfect case to try.
YES! I would give you a 'like', but for some reason my browser I guess is preventing me from 'liking'. At least I can reply! ; )
Thank you so much for all your work.
Please could you explain what "safely" means (in terms of dosage) in this sentence: "Rather, the only combination I am aware of is nebulized glutathione and DMSO, which (provided it’s done safely) is remarkably effective for asthma and otherwise incurable respiratory conditions"
It's explained in the COPD article
The COPD article only explains how to nebulize glutathione. I would like to know how to nebulize glutathione together with DMSO.
https://www.midwesterndoctor.com/p/dmso-heals-the-lungs-and-cures-chronic-35a
This section: Nebulizing DMSO
Thank you, I just wondered about the safety of combining glutathione with DMSO, but Danbob has explained. I have been combining DMSO with 3% hydrogen peroxide in a 0.9% isotonic saline solution at the doses you recommended (ie. very low, 2 drops DMSO + 5 drops HP in 5 ml saline) but have found no benefit and some worsening. So it's the mechanics of the combination synergy effect of DMSO + something else that I do not understand. For example, if I nebulize DMSO in saline, do I have to follow immediately with the glutathione (or whatever it is) to get the DMSO turbocharged effect? Or could I still get the turbocharged effect if I do DMSO in the morning and e.g. glutathione in the evening? Or do I need to nebulize both simultaneously to get the DMSO turbocharged effect?
Rinse your nebulizer set with 99% dmso, then water. Then add 2.5mL nebulizer solution and add 1-3 drops of pure, pharma grade dmso. Can then nebulize Glutathione. Some don't bother and just do them together.
Thanks. That is what I wondered. Together or separately, with or without a time interval, on the same day or alternating days -- that kind of thing.
Did that answer your question?
Well mostly, but I wonder if there is any drug interaction between DMSO and glutathione, even if one takes them separately. I was just a bit alerted by the phrase "provided it's done safely". How would it not be done safely?
That statement is about following the basic guidelines and being smart about DMSO's use rather than just jumping into without informing one's self. This is one of the purposes of all AMD's articles: to relay enough info so people can be safe, ie: not putting 99% in your eye, or not using it concurrently with heroin, etc. There's still alot we don't know but I believe the author has laid out some good general boundaries that can be used to guide DMSO's home use. Example: it is a vehicle for other substances and can increase their action. Meaning: If you spilled gas yourself, it would be wise to wash it off before using DMSO. Or, if you're on blood pressure (any med) medicine, you should wait until your medicine has absorbed before taking a dose of DMSO. Regarding DMSO and glutathione, there is a chance that high enough doses of each could interact and render them both inneffective. For this reason, I'd use dmso, wait a few minutes, then use the glutathione.
Hi Danbob, I take BP med each morning. How do I know when it is absorbed before I use DMSO on my sore knees? Thank you.
Hi Patricia! I don't worry about this issue topically. I just apply and go. Leave on for at least 15-20 mins. If taking orally, its best to wait 2-4 hours after you take your meds. Generally, very safe. For the knees, I'm fond of applying DMSO, then about a nickel sized amount of Diclofenac gel spread on top. I had a miraculous response in a guy who was post total knee replacement. Ortho left one leg 1/2 in shorter than the other. On all the pain meds. Ortho got an xray and "everything was fine." Not even kidding, he called my nurse the very next morning to report he was conpletely pain free. No more pain meds and a real success in my book.
Thank you so much! I’m delighted for your patient. Well done! I’ll follow your suggestions.
Dear Midwestern Doctor,
Some claim you can make CDS with Safrax tablets (https://safrax.com/shop/). I was wondering your thoughts on this as it would be much easier than Andreas Kalcker's method. Thanks!
I really don't know. There are solid activators (some of which are toxic) but I do not know what that one contains, and it's not listed anywhere. Excluding that, it does allow you to control the dose which is great.
I had reached out to the company a couple years ago and have copied their reply below. If you have time, please reply to let me know if you think it would be safe & if it would result in the same outcome as Andreas Kalcker's method. Thanks!
Thank you for your interest in our chlorine dioxide tablets!The ingredients of our tablets are:
- Sodium Chlorite,
- Magnesium Sulfate,
- Sodium Bisulfate (acid activator).
When the tablets are mixed with water, it becomes pure Chlorine Dioxide (purity is 97 to 99% depending on laboratory used), the rest is just common salt.
Our tablets are compatible with organic culture and fruits and vegetables processing. Our acid activator is Sodium Bisulfate and not acid, so we do not have residuals of chlorate and perchlorate (long term thyroid side effect), which is monitored and regulated in Europe. I hope I was able to answer your question, please do not hesitate if you have any further questions.
Thank you and have a great day!
Jimmie Thomas
Water & Sanitation Specialist
"Except for his 2015 book, which is in German,"
Should that be "in English" ? The book is in English over at Amazon.
Yes. Everything besides that is in German.
1) I wanted to go with the lower doses to avoid any risk. The other issue is that at higher concentrations it can leach plastic. That said, sometimes there are excellent results like yours.
2) With gums, part of the reason lower concentrations are advised is to avoid issues for people with fillings with materials that can be leached.
3) Never heard of that use for DMSO, I will need to tell some of my colleagues about that. I will look up Syrian Rue for benzos, I have not heard of that either.
4) Generally it sounds like you tolerate higher doses than most people. There is a lot of variability in the dosing, so I was trying to present what would be the best fit for the most number of people.
5) DMSO helps people get more restful sleep.
I took a larger dose of syrian rue once (8 caps), and spent a lot of time throwing up afterwards, maybe an hour later. It was remarkable that it was completely not-unpleasant, normally throwing up is gaggy and hard on the body. This was easy! I was hiking, puked, continued to hike, puked again, no problem. No gagging or heaving. :-)
That was a focus of this article. Has to be in combination with other antilyme agents unless you are just trying to heal symptoms of lyme rather than to eliminate the infection.
https://open.substack.com/pub/amidwesterndoctor/p/dmso-transforms-the-treatment-of?utm_source=share&utm_medium=android&r=dumok
Lyme's not mentioned specifically. Is this just for general ideas for infections?
Yes. TB for example is typically treated with several antibiotics, however DMSO's properties allow it to be treated with fewer due to the potentiation. The same is probably true with tick borne illness and biofilms. Just as we've seen in cancer, DMSO can transport the meds through biologic barriers that prohibit standalone therapies. Although I haven't seen it, I'm fairly certain someone has done it and written about it. My idea would be DMSO+clove oil+ doxy or piperacillin or garlic oil.